RO95366A2 - PROCESS FOR OBTEHIR 10,11-DIHYDRO-N, N-DIMETHYL-5H-DIBENZO- (A, D) -CYCLOHEPTENE-5-HYDROXY-5-PROPYLATIN - Google Patents
PROCESS FOR OBTEHIR 10,11-DIHYDRO-N, N-DIMETHYL-5H-DIBENZO- (A, D) -CYCLOHEPTENE-5-HYDROXY-5-PROPYLATINInfo
- Publication number
- RO95366A2 RO95366A2 RO86126010A RO12601086A RO95366A2 RO 95366 A2 RO95366 A2 RO 95366A2 RO 86126010 A RO86126010 A RO 86126010A RO 12601086 A RO12601086 A RO 12601086A RO 95366 A2 RO95366 A2 RO 95366A2
- Authority
- RO
- Romania
- Prior art keywords
- hydroxy
- propylatin
- obtehir
- cycloheptene
- dibenzo
- Prior art date
Links
- 238000003747 Grignard reaction Methods 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 abstract 1
- 229940001470 psychoactive drug Drugs 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
10,11-di:hydro-N,N-di:methyl -5H-di:benzo-(a,d)-cyclo-heptene -5-hydroxy -5-propylamine, an intermediate cpd. for the prepn. of a psychotropic drug, is prepd. by a Grignard reaction between 10,11-di:hydro-5H-di:benzo -(a,d)-cycloheptane-5-one and 1,3-di:methyl-amino -chloro-propane. The ketone, which is not separated from its reaction mix. is obtd. in a pure state, through distillation under pronounced vacuum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO95366A2 true RO95366A2 (en) | 1988-09-15 |
| RO95366B1 RO95366B1 (en) | 1988-09-16 |
Family
ID=20120202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO126010A RO95366B1 (en) | 1986-12-22 | 1986-12-22 | Process for preparing 10,11-dihydro-n,n-dimethyl-5h-dibenzo-(a,d)-cycloheptene-5- hydroxy-5-propylamine |
Country Status (1)
| Country | Link |
|---|---|
| RO (1) | RO95366B1 (en) |
-
1986
- 1986-12-22 RO RO126010A patent/RO95366B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO95366B1 (en) | 1988-09-16 |
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