RO93562B - Process for tableting delayed effect medicines - Google Patents

Process for tableting delayed effect medicines

Info

Publication number
RO93562B
RO93562B RO120458A RO12045885A RO93562B RO 93562 B RO93562 B RO 93562B RO 120458 A RO120458 A RO 120458A RO 12045885 A RO12045885 A RO 12045885A RO 93562 B RO93562 B RO 93562B
Authority
RO
Romania
Prior art keywords
tableting
delayed effect
polyvinyl butyral
effect medicines
delayed
Prior art date
Application number
RO120458A
Other languages
Romanian (ro)
Other versions
RO93562A (en
Inventor
Ferencne Kubala
Istvan Danicska
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of RO93562A publication Critical patent/RO93562A/en
Publication of RO93562B publication Critical patent/RO93562B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Inventia se refera la un procedeu pentru tabletare de medicamente cu efect întîrziat cu ajutorul unor polimeri inerti, care consta în aceea ca substanta activa si substantele ajutatoare sînt umectate cu o solutie continînd 2...8% polivinilbutiral dizolvat într-un solvent ales dintre etanol, izopropanol, cloroform sau amestecul lor si apoi sunt granulate, granulele sînt presate în tablete si sînt fie tratate termic la 50...53 degree C, fie acoperite cu un strat de polivinilbutiral.The invention relates to a process for tabletting medicaments delayed by inert polymers which consists in that the active substance and the auxiliaries are moistened with a solution containing 2-8% polyvinyl butyral dissolved in a solvent selected from ethanol , isopropanol, chloroform or their mixture and then granulated, the granules are pressed into tablets and either thermally treated at 50 DEG-53 DEG C or coated with a layer of polyvinyl butyral.

RO120458A 1984-02-21 1985-02-14 Process for tableting delayed effect medicines RO93562B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU84686A HU191246B (en) 1984-02-21 1984-02-21 Process for producing oral pharmaceutical compositions of retaed activity

Publications (2)

Publication Number Publication Date
RO93562A RO93562A (en) 1987-12-31
RO93562B true RO93562B (en) 1988-01-02

Family

ID=10950851

Family Applications (1)

Application Number Title Priority Date Filing Date
RO120458A RO93562B (en) 1984-02-21 1985-02-14 Process for tableting delayed effect medicines

Country Status (10)

Country Link
BG (1) BG51340A3 (en)
CS (1) CS251786B2 (en)
DD (1) DD231985A5 (en)
HU (1) HU191246B (en)
IT (1) IT1185513B (en)
PL (1) PL145663B1 (en)
RO (1) RO93562B (en)
SU (1) SU1720474A3 (en)
WO (1) WO1985003636A1 (en)
YU (1) YU45233B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1204294B (en) * 1986-03-11 1989-03-01 Gentili Ist Spa METHOD OF MANUFACTURE OF GRANULARS SUITABLE FOR THE PRODUCTION OF COATED TABLETS, FOR ORAL USE, WITH CONTROLLED RELEASE
WO1992011845A1 (en) * 1991-01-03 1992-07-23 Glaxo Canada Inc. Method for production of solid pharmaceutical preparation
HUT72408A (en) * 1993-09-10 1996-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing tablets containing acetyl-salicylic acid
US6258381B1 (en) * 2000-02-11 2001-07-10 Mcneil-Ppc, Inc. Tablet and process for making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919436A (en) * 1971-09-27 1975-11-11 Eisai Co Ltd Process for preparation of coated medicines
DE2347713C3 (en) * 1972-09-25 1980-03-06 Warner-Lambert Co., Morris Plains, N.J. (V.St.A.) Acetylsalicylic acid chewable tablet
DE2446058A1 (en) * 1974-09-26 1976-04-08 Henning Berlin Gmbh GALENIC PREPARATION FOR ALLOPURINOL CONTINUOUS THERAPY
JPS5837285B2 (en) * 1975-05-29 1983-08-15 カブシキガイシヤ ミドリジユウジ It is very difficult to understand the situation.

Also Published As

Publication number Publication date
DD231985A5 (en) 1986-01-15
YU26685A (en) 1988-02-29
HUT37356A (en) 1985-12-28
BG51340A3 (en) 1993-04-15
PL145663B1 (en) 1988-10-31
WO1985003636A1 (en) 1985-08-29
SU1720474A3 (en) 1992-03-15
HU191246B (en) 1987-01-28
IT8519584A0 (en) 1985-02-21
CS127885A2 (en) 1986-12-18
PL252062A1 (en) 1985-12-03
IT1185513B (en) 1987-11-12
YU45233B (en) 1992-05-28
RO93562A (en) 1987-12-31
CS251786B2 (en) 1987-08-13

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