RO81354B - Process for preparing the macrolide antibiotic - tylactone - Google Patents
Process for preparing the macrolide antibiotic - tylactoneInfo
- Publication number
- RO81354B RO81354B RO104734A RO10473481A RO81354B RO 81354 B RO81354 B RO 81354B RO 104734 A RO104734 A RO 104734A RO 10473481 A RO10473481 A RO 10473481A RO 81354 B RO81354 B RO 81354B
- Authority
- RO
- Romania
- Prior art keywords
- dideoxythionolide
- dihydro
- macrolide
- macrolide antibiotic
- tylactone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
- C23F11/00—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent
- C23F11/06—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent in markedly alkaline liquids
Abstract
Procedeu de preparare a antibioticului macrolid tilactona, 20-dihidro 20, 23-dideoxitilonolida cu formula generala I: (vezi formula) caracterizat prin aceea ca microorganismul Streptomices frediae NRRL 12188 se supune cultivarii în conditii aerobe submerse, într-un mediu de cultura continînd surse de carbon alese dintre dextrina, glucoza, amidon si faina de porumb, precum si uleiuri vegetale, de preferinta aminiacizi, ape de la înmuierea porumbului, melasa, lecitina, extract de drojdie de bere,precumsi saruri nutritive, fermentarea avînd loc la temperaturi între 10 si 40 degree C, de preferinta 28 degree C, pîna la obtinerea unei cantitati substantiale de produs, dupa care se procedeaza la recuperarea acestuia, respectiv a macrolidei 20-dihidro-20, 23-dideoxitilonolida (tilactona) prin procedee în sine cunoscute, si daca se doreste poate fi transformata mai departe în derivati acilici.Process for the preparation of the 20-dihydro 20,23-dideoxythionolide macrolide antibiotic of general formula I (see formula) characterized in that the microorganism Streptomyces frediae NRRL 12188 is cultured under submerged aerobic conditions in a culture medium containing sources of carbon selected from dextrin, glucose, starch and corn flour, as well as vegetable oils, preferably amino acids, maize softening water, molasses, lecithin, brewer's yeast extract, and nutritive salts, fermenting at temperatures between 10 and 40 ° C, preferably 28 ° C, until a substantial amount of the product is obtained, after which the 20-dihydro-20,23-dideoxythionolide (tilactone) macrolide is recovered by methods known per se, and if desired, it can be further converted into acyl derivatives.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16397580A | 1980-06-30 | 1980-06-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO81354A RO81354A (en) | 1983-02-15 |
| RO81354B true RO81354B (en) | 1983-02-28 |
Family
ID=22592441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO104734A RO81354B (en) | 1980-06-30 | 1981-06-30 | Process for preparing the macrolide antibiotic - tylactone |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0043525B1 (en) |
| JP (1) | JPS604272B2 (en) |
| AR (1) | AR228276A1 (en) |
| AT (1) | ATE10293T1 (en) |
| AU (1) | AU542053B2 (en) |
| BR (1) | BR8104104A (en) |
| CA (1) | CA1158852A (en) |
| CS (1) | CS242870B2 (en) |
| DE (1) | DE3167178D1 (en) |
| ES (1) | ES503481A0 (en) |
| GR (1) | GR75712B (en) |
| HU (1) | HU185932B (en) |
| IN (1) | IN154625B (en) |
| MX (1) | MX161784A (en) |
| NO (1) | NO163537C (en) |
| NZ (1) | NZ197575A (en) |
| PH (1) | PH16622A (en) |
| PL (2) | PL130311B1 (en) |
| RO (1) | RO81354B (en) |
| ZA (1) | ZA814278B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60180877U (en) * | 1984-05-14 | 1985-11-30 | 新潟ビ−．エス．アンド．ビ−．セイフテイ．システムズ株式会社 | Retaining structure of welded rupture disc |
| JPS6254696U (en) * | 1985-09-24 | 1987-04-04 | ||
| JPH02119192U (en) * | 1989-03-13 | 1990-09-26 | ||
| JPH02122691U (en) * | 1989-03-15 | 1990-10-08 | ||
| AR010696A1 (en) | 1996-12-12 | 2000-06-28 | Sasol Tech Pty Ltd | A METHOD FOR THE ELIMINATION OF CARBON DIOXIDE FROM A PROCESS GAS |
| FR2994861B1 (en) | 2012-08-30 | 2014-08-22 | IFP Energies Nouvelles | PROCESS FOR ABSORPTION OF ACIDIC COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT BY MEANS OF AQUEOUS AMINO ACID SOLUTION |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3808140A (en) * | 1970-07-13 | 1974-04-30 | B Mago | Antimony-vanadium corrosion inhibitors for alkanolamine gas treating system |
| US3896044A (en) * | 1971-11-22 | 1975-07-22 | Union Carbide Corp | Nitro-substituted aromatic acid corrosion inhibitors for alkanolamine gas treating system |
| US3959170A (en) * | 1971-11-22 | 1976-05-25 | Union Carbide Corporation | Corrosion inhibitors for alkanolamine gas treating system |
| US3951844A (en) * | 1974-04-29 | 1976-04-20 | Union Carbide Corporation | Corrosion inhibition of aqueous potassium carbonate gas treating systems |
-
1981
- 1981-06-24 NO NO812157A patent/NO163537C/en unknown
- 1981-06-24 ZA ZA814278A patent/ZA814278B/en unknown
- 1981-06-24 IN IN682/CAL/81A patent/IN154625B/en unknown
- 1981-06-26 AT AT81104985T patent/ATE10293T1/en active
- 1981-06-26 EP EP81104985A patent/EP0043525B1/en not_active Expired
- 1981-06-26 CA CA000380674A patent/CA1158852A/en not_active Expired
- 1981-06-26 DE DE8181104985T patent/DE3167178D1/en not_active Expired
- 1981-06-27 JP JP56100386A patent/JPS604272B2/en not_active Expired
- 1981-06-29 GR GR65370A patent/GR75712B/el unknown
- 1981-06-29 AR AR285900A patent/AR228276A1/en active
- 1981-06-29 CS CS814945A patent/CS242870B2/en unknown
- 1981-06-29 PH PH25830A patent/PH16622A/en unknown
- 1981-06-29 BR BR8104104A patent/BR8104104A/en unknown
- 1981-06-29 ES ES503481A patent/ES503481A0/en active Granted
- 1981-06-29 HU HU811888A patent/HU185932B/en unknown
- 1981-06-29 PL PL1981239063A patent/PL130311B1/en unknown
- 1981-06-29 MX MX188064A patent/MX161784A/en unknown
- 1981-06-30 NZ NZ197575A patent/NZ197575A/en unknown
- 1981-06-30 AU AU72401/81A patent/AU542053B2/en not_active Ceased
- 1981-06-30 RO RO104734A patent/RO81354B/en unknown
- 1981-09-26 PL PL1981231927A patent/PL127863B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO812157L (en) | 1982-01-04 |
| PL130311B1 (en) | 1984-07-31 |
| CS494581A2 (en) | 1984-06-18 |
| RO81354A (en) | 1983-02-15 |
| ES8300875A1 (en) | 1982-11-16 |
| NO163537C (en) | 1990-06-13 |
| ATE10293T1 (en) | 1984-11-15 |
| AU7240181A (en) | 1982-01-07 |
| DE3167178D1 (en) | 1984-12-20 |
| AR228276A1 (en) | 1983-02-15 |
| MX161784A (en) | 1990-12-27 |
| ES503481A0 (en) | 1982-11-16 |
| EP0043525B1 (en) | 1984-11-14 |
| PH16622A (en) | 1983-11-28 |
| CA1158852A (en) | 1983-12-20 |
| PL231927A1 (en) | 1982-03-15 |
| EP0043525A1 (en) | 1982-01-13 |
| AU542053B2 (en) | 1985-02-07 |
| GR75712B (en) | 1984-08-02 |
| BR8104104A (en) | 1982-03-16 |
| IN154625B (en) | 1984-11-24 |
| JPS5739178A (en) | 1982-03-04 |
| HU185932B (en) | 1985-04-28 |
| JPS604272B2 (en) | 1985-02-02 |
| PL127863B1 (en) | 1983-12-31 |
| ZA814278B (en) | 1982-07-28 |
| NO163537B (en) | 1990-03-05 |
| NZ197575A (en) | 1984-10-19 |
| CS242870B2 (en) | 1986-05-15 |
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