RO63871A - Procede pour la preparation des derives du pyrazolo-(1,5-a)-pyrymidine - Google Patents

Procede pour la preparation des derives du pyrazolo-(1,5-a)-pyrymidine

Info

Publication number
RO63871A
RO63871A RO7200071971A RO7197172A RO63871A RO 63871 A RO63871 A RO 63871A RO 7200071971 A RO7200071971 A RO 7200071971A RO 7197172 A RO7197172 A RO 7197172A RO 63871 A RO63871 A RO 63871A
Authority
RO
Romania
Prior art keywords
pyrymidine
pyrazolo
derivatives
preparation
pyrymidine derivatives
Prior art date
Application number
RO7200071971A
Other languages
English (en)
French (fr)
Inventor
Robert Springer
Darrell O'brien
Lionel Simon
Original Assignee
Int Chem & Nuclear Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Chem & Nuclear Corp filed Critical Int Chem & Nuclear Corp
Publication of RO63871A publication Critical patent/RO63871A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO7200071971A 1971-08-16 1972-08-16 Procede pour la preparation des derives du pyrazolo-(1,5-a)-pyrymidine RO63871A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17219571A 1971-08-16 1971-08-16
US261103A US3920652A (en) 1971-08-16 1972-06-08 Aromatic substituted pyrazola {8 1,5a{9 {0 pyrimidine compounds useful as xanthine oxidase inhibitors

Publications (1)

Publication Number Publication Date
RO63871A true RO63871A (fr) 1979-01-15

Family

ID=26867834

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7200071971A RO63871A (fr) 1971-08-16 1972-08-16 Procede pour la preparation des derives du pyrazolo-(1,5-a)-pyrymidine

Country Status (19)

Country Link
US (1) US3920652A (ro)
JP (1) JPS4834899A (ro)
AR (1) AR193536A1 (ro)
AT (1) AT330780B (ro)
BE (1) BE786611A (ro)
BG (1) BG19806A3 (ro)
DD (1) DD99581A5 (ro)
DE (1) DE2236987A1 (ro)
ES (1) ES405663A1 (ro)
FR (1) FR2150771B1 (ro)
GB (1) GB1359563A (ro)
HU (1) HU167466B (ro)
IE (1) IE36629B1 (ro)
IL (1) IL39988A0 (ro)
LU (1) LU65892A1 (ro)
MC (1) MC937A1 (ro)
NL (1) NL7211011A (ro)
RO (1) RO63871A (ro)
SU (1) SU522800A3 (ro)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093617A (en) * 1974-11-12 1978-06-06 Icn Pharmaceuticals, Inc. 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines
US4048184A (en) * 1976-11-15 1977-09-13 E. R. Squibb & Sons, Inc. 6-Phenyl-2H-pyrazolo[3,4-b]pyridines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
AU557300B2 (en) * 1982-03-16 1986-12-18 Farmitalia Carlo Erba S.P.A. Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
KR927003595A (ko) * 1990-10-09 1992-12-18 오츠카 아키히코 피리미딘 유도체, 이의 제조방법 및 안드로겐 저해제
AU667575B2 (en) * 1992-10-20 1996-03-28 Otsuka Pharmaceutical Co., Ltd. Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor
CA2206080A1 (en) * 1995-09-28 1997-04-03 Otsuka Pharmaceutical Factory, Inc. Analgesic composition_of pryazolo{1,5-a}pyrimidine derivatives
US6664261B2 (en) * 1996-02-07 2003-12-16 Neurocrine Biosciences, Inc. Pyrazolopyrimidines as CRF receptor antagonists
US7094782B1 (en) * 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
RO121272B1 (ro) * 1996-07-24 2007-02-28 The Du Pont Merck Pharmaceutical Company Azolotriazine şi pirimidine
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US6235741B1 (en) * 1997-05-30 2001-05-22 Merck & Co., Inc. Angiogenesis inhibitors
AU1520699A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Methods for treatment of disorders of cardiac contractility
US6380203B1 (en) * 1998-01-14 2002-04-30 Merck & Co., Inc. Angiogenesis inhibitors
WO2000059907A2 (en) * 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolotriazines as crf antagonists
AU4203500A (en) 1999-04-06 2000-10-23 Du Pont Pharmaceuticals Company Pyrazolopyrimidines as crf antagonists
US6630476B2 (en) 2000-07-07 2003-10-07 Bristol-Myers Squibb Pharma Company Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists
DE112015002679T5 (de) 2014-06-06 2017-04-20 Siemens Medical Solutions Usa, Inc. Gammakamera-totzeitbestimmung in echtzeit unter verwendung langlebiger radioisotope

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3048587A (en) * 1960-10-17 1962-08-07 Ortho Pharma Corp 2-alkylamino-4-aminopyrimidine
US3296268A (en) * 1965-10-19 1967-01-03 Searle & Co 3-cyanoethyl-2-oxo-5-phenyl [1, 5-a] pyrimidines

Also Published As

Publication number Publication date
ATA677372A (de) 1975-10-15
IE36629B1 (en) 1977-01-19
DD99581A5 (ro) 1973-08-12
AR193536A1 (es) 1973-04-30
DE2236987A1 (de) 1973-03-01
FR2150771A1 (ro) 1973-04-13
FR2150771B1 (ro) 1976-05-21
IL39988A0 (en) 1972-09-28
US3920652A (en) 1975-11-18
GB1359563A (en) 1974-07-10
IE36629L (en) 1973-02-16
ES405663A1 (es) 1976-01-16
NL7211011A (ro) 1973-02-20
JPS4834899A (ro) 1973-05-22
SU522800A3 (ru) 1976-07-25
HU167466B (ro) 1975-10-28
BE786611A (fr) 1973-01-22
LU65892A1 (ro) 1973-01-15
AT330780B (de) 1976-07-26
BG19806A3 (ro) 1975-10-10
MC937A1 (fr) 1973-08-10

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