RO118794B1 - Metodă de tratament a unor stări dependente de steroizii gonadici - Google Patents

Metodă de tratament a unor stări dependente de steroizii gonadici

Info

Publication number
RO118794B1
RO118794B1 RO97-00117A RO9700117A RO118794B1 RO 118794 B1 RO118794 B1 RO 118794B1 RO 9700117 A RO9700117 A RO 9700117A RO 118794 B1 RO118794 B1 RO 118794B1
Authority
RO
Romania
Prior art keywords
gonadal
treatment
dependent conditions
steroid dependent
estrogen
Prior art date
Application number
RO97-00117A
Other languages
English (en)
Inventor
Gary D. Hogden
Audrey Philips
Original Assignee
Eastern Virginia Medical School
Ortho Pharmaceutical Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastern Virginia Medical School, Ortho Pharmaceutical Corporation filed Critical Eastern Virginia Medical School
Priority claimed from PCT/US1995/008996 external-priority patent/WO1996003138A1/en
Publication of RO118794B1 publication Critical patent/RO118794B1/ro

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

Invenţia se referă la o metodă de tratament a unor stări dependente de steroizii gonadici la un mamifer, prin reducerea furnizării de estrogen şi constă în aceea că se administrează un antagonist de GnRH într-o cantitate eficientă pentru a inhiba proliferarea ţesutului endometrial, fără stoparea substanţială a producţiei de estrogen endogen.
RO97-00117A 1994-07-22 1995-07-18 Metodă de tratament a unor stări dependente de steroizii gonadici RO118794B1 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27959394A 1994-07-22 1994-07-22
US08/467,860 US5658884A (en) 1994-07-22 1995-06-06 Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens
PCT/US1995/008996 WO1996003138A1 (en) 1994-07-22 1995-07-18 Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens

Publications (1)

Publication Number Publication Date
RO118794B1 true RO118794B1 (ro) 2003-11-28

Family

ID=23069633

Family Applications (1)

Application Number Title Priority Date Filing Date
RO97-00117A RO118794B1 (ro) 1994-07-22 1995-07-18 Metodă de tratament a unor stări dependente de steroizii gonadici

Country Status (8)

Country Link
US (1) US5658884A (ro)
KR (1) KR970704460A (ro)
JO (1) JO1879B1 (ro)
LT (1) LT4341B (ro)
MY (1) MY121568A (ro)
RO (1) RO118794B1 (ro)
UA (1) UA51627C2 (ro)
ZA (1) ZA956099B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265393B1 (en) 1998-08-07 2001-07-24 Heinrichs William Leroy Prevention of endometriosis signs or symptons
US6703367B1 (en) 1999-04-27 2004-03-09 Praecis Pharmaceuticals Inc. Methods for treating hot flashes and gynaecomastia
US7005418B1 (en) * 1999-09-23 2006-02-28 Zentaris Gmbh Method for the therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction
BR0014198A (pt) * 1999-09-23 2002-05-21 Zentaris Ag Processo para o gerenciamento terapêutico da proliferação extra-uterina de tecido endometrial, dor pélvica crÈnica e obstrução da tuba de falópio
US20130191934A1 (en) * 2010-10-01 2013-07-25 Indiana University Research And Technology Corpora Treatment of symptoms associated with menopause
EP3560555A1 (en) * 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211952A (en) * 1991-04-12 1993-05-18 University Of Southern California Contraceptive methods and formulations for use therein

Also Published As

Publication number Publication date
LT97021A (en) 1998-02-25
US5658884A (en) 1997-08-19
MY121568A (en) 2006-02-28
KR970704460A (ko) 1997-09-06
UA51627C2 (uk) 2002-12-16
JO1879B1 (en) 1996-07-25
ZA956099B (en) 1997-02-18
LT4341B (lt) 1998-05-25

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