PT95564A - Processo para a preparacao de (+)-ibuprofen-d-aminoacido uteis como analgesicos intensificados de ataque acelerado - Google Patents
Processo para a preparacao de (+)-ibuprofen-d-aminoacido uteis como analgesicos intensificados de ataque aceleradoInfo
- Publication number
- PT95564A PT95564A PT95564A PT9556490A PT95564A PT 95564 A PT95564 A PT 95564A PT 95564 A PT95564 A PT 95564A PT 9556490 A PT9556490 A PT 9556490A PT 95564 A PT95564 A PT 95564A
- Authority
- PT
- Portugal
- Prior art keywords
- ibuprofen
- uteis
- aminoacides
- intensified
- analgesics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42246689A | 1989-10-17 | 1989-10-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT95564A true PT95564A (pt) | 1991-08-14 |
| PT95564B PT95564B (pt) | 1997-11-28 |
Family
ID=23675012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95564A PT95564B (pt) | 1989-10-17 | 1990-10-11 | Processo para a preparacao de (+)-ibuprofen-d-aminoacido uteis como analgesicos intensificados de ataque acelerado |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0424028B1 (pt) |
| JP (1) | JPH03206064A (pt) |
| KR (1) | KR910007858A (pt) |
| AT (1) | ATE128452T1 (pt) |
| AU (1) | AU635074B2 (pt) |
| CA (1) | CA2027624A1 (pt) |
| DE (1) | DE69022678T2 (pt) |
| DK (1) | DK0424028T3 (pt) |
| IE (1) | IE68508B1 (pt) |
| PT (1) | PT95564B (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT59656A (en) * | 1990-11-15 | 1992-06-29 | Puetter Medice Chem Pharm | Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components |
| HUT59653A (en) * | 1990-11-15 | 1992-06-29 | Puetter Medice Chem Pharm | Process for producing complexes containing s/+/-phenyl-alcanoic acids and alpha-hydroxy-alcanoic acids and pharmaceutical compositions containing them as active components |
| US5552160A (en) * | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
| GB9200114D0 (en) * | 1992-01-04 | 1992-02-26 | Scras | Dual inhibitors of no synthase and cyclooxygenase |
| FR2687673B1 (fr) * | 1992-01-13 | 1995-07-07 | Jung Jean | Sels amines d'acides arylcarboxyliques, sterilisables, solubles dans l'eau, utilises en ophtalmologie et/ou dans la sphere otorhinolaryngologique. |
| DE69309958T2 (de) * | 1992-12-02 | 1997-07-24 | Knoll Ag | Verfahren zur herstellung von im wesentlichen enantiomeren der phenylpropionsäuren |
| IT1264856B1 (it) * | 1993-06-21 | 1996-10-17 | Zambon Spa | Composizione farmaceutica ad attivita' analgesica |
| IT1264855B1 (it) * | 1993-06-21 | 1996-10-17 | Zambon Spa | Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici |
| IT1266583B1 (it) * | 1993-07-30 | 1997-01-09 | Zambon Spa | Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico |
| KR970701041A (ko) * | 1994-02-24 | 1997-03-17 | 히데아키 고리 | 진통 작용 증진 제제(analgesic activity enhancer) |
| ES2105948B1 (es) * | 1994-10-31 | 1998-07-01 | Zambon Spa | Procedimiento para la preparacion de sales de acido 2-(4-isobutilfenil) propionico. |
| US7914814B2 (en) | 1997-09-17 | 2011-03-29 | Strategic Science & Technologies, Llc | Topical delivery of arginine of cause beneficial effects |
| AU737199B2 (en) * | 1997-09-17 | 2001-08-09 | Strategic Science & Technologies, Llc | A delivery of arginine to cause beneficial effects |
| KR100523242B1 (ko) * | 2000-05-18 | 2005-10-24 | 한미약품 주식회사 | 이부프로펜을 함유하는 정제 조성물 |
| ES2429443T3 (es) | 2004-04-19 | 2013-11-14 | Strategic Science & Technologies, Llc | Suministro transdérmico de sustancias beneficiosas efectuado mediante un entorno de fuerza iónica elevada |
| US9226909B2 (en) | 2004-04-19 | 2016-01-05 | Strategic Science & Technologies, Llc | Beneficial effects of increasing local blood flow |
| ES2303468B1 (es) * | 2007-01-22 | 2009-06-08 | Masterfarm, S.L | "una composicion farmaceutica pulverulenta que comprende ibuprofeno". |
| US9072659B2 (en) | 2009-06-24 | 2015-07-07 | Strategic Science & Technologies, Llc | Topical composition containing naproxen |
| EP2445492B1 (en) | 2009-06-24 | 2016-09-28 | Strategic Science & Technologies, LLC | Topical composition containing ibuprofen |
| US11684624B2 (en) | 2009-06-24 | 2023-06-27 | Strategic Science & Technologies, Llc | Treatment of erectile dysfunction and other indications |
| CN101978955A (zh) * | 2010-11-05 | 2011-02-23 | 航天中心医院 | 右旋布洛芬氨基酸盐片剂及其制备方法 |
| ES2811515T3 (es) | 2010-12-29 | 2021-03-12 | Strategic Science & Tech Llc | Tratamiento de disfunción eréctil y otras indicaciones |
| JP2014501283A (ja) | 2010-12-29 | 2014-01-20 | ストラテジック サイエンス アンド テクノロジーズ， エルエルシー | アレルギーおよび他の適応症の処置のためのシステムおよび方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH377368A (de) * | 1960-04-07 | 1964-05-15 | Inventa Ag | Verfahren zur Reinigung von 1(+)-Lysin |
| IT1059677B (it) * | 1974-03-22 | 1982-06-21 | Neopharmed Spa | Sale di lisina ad azione terapeutica |
| DE3669103D1 (de) * | 1986-11-14 | 1990-04-05 | Puetter Medice Chem Pharm | Ibuprofen enthaltendes arzneimittel. |
| US4851444A (en) * | 1987-07-10 | 1989-07-25 | Analgesic Associates | Onset-hastened/enhanced analgesia |
-
1990
- 1990-10-11 EP EP90311150A patent/EP0424028B1/en not_active Expired - Lifetime
- 1990-10-11 AT AT90311150T patent/ATE128452T1/de not_active IP Right Cessation
- 1990-10-11 DK DK90311150.8T patent/DK0424028T3/da active
- 1990-10-11 PT PT95564A patent/PT95564B/pt not_active IP Right Cessation
- 1990-10-11 DE DE69022678T patent/DE69022678T2/de not_active Expired - Fee Related
- 1990-10-15 CA CA002027624A patent/CA2027624A1/en not_active Abandoned
- 1990-10-16 AU AU64692/90A patent/AU635074B2/en not_active Ceased
- 1990-10-16 KR KR1019900016429A patent/KR910007858A/ko not_active Application Discontinuation
- 1990-10-16 IE IE371790A patent/IE68508B1/en not_active IP Right Cessation
- 1990-10-17 JP JP2276564A patent/JPH03206064A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0424028B1 (en) | 1995-09-27 |
| DE69022678T2 (de) | 1996-03-21 |
| JPH03206064A (ja) | 1991-09-09 |
| CA2027624A1 (en) | 1991-04-18 |
| EP0424028A2 (en) | 1991-04-24 |
| IE68508B1 (en) | 1996-06-26 |
| DK0424028T3 (da) | 1996-01-29 |
| AU6469290A (en) | 1991-04-26 |
| AU635074B2 (en) | 1993-03-11 |
| EP0424028A3 (en) | 1992-06-10 |
| PT95564B (pt) | 1997-11-28 |
| DE69022678D1 (de) | 1995-11-02 |
| KR910007858A (ko) | 1991-05-30 |
| IE903717A1 (en) | 1991-04-24 |
| ATE128452T1 (de) | 1995-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19910320 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19970820 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20050221 |