PT92552A - Processo de producao de sequencias de adn que codificam proteinas inibidoras da serina-protease, e de producao daquelas proteinas, de medicamentos que as contem e de vectores de expressao contendo as sequencias de adn - Google Patents

Processo de producao de sequencias de adn que codificam proteinas inibidoras da serina-protease, e de producao daquelas proteinas, de medicamentos que as contem e de vectores de expressao contendo as sequencias de adn

Info

Publication number
PT92552A
PT92552A PT92552A PT9255289A PT92552A PT 92552 A PT92552 A PT 92552A PT 92552 A PT92552 A PT 92552A PT 9255289 A PT9255289 A PT 9255289A PT 92552 A PT92552 A PT 92552A
Authority
PT
Portugal
Prior art keywords
proteins
dna sequences
synthesis
production
dna
Prior art date
Application number
PT92552A
Other languages
English (en)
Other versions
PT92552B (pt
Inventor
Leopold Flohe
Gerd J Steffens
Regina Heinzel-Wieland
Joachim Ammann
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of PT92552A publication Critical patent/PT92552A/pt
Publication of PT92552B publication Critical patent/PT92552B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT92552A 1988-12-13 1989-12-12 Processo de producao de sequencias de adn que codificam proteinas inibidoras da serina-protease, e de producao daquelas proteinas, de medicamentos que as contem e de vectores de expressao contendo as sequencias de adn PT92552B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3841873A DE3841873A1 (de) 1988-12-13 1988-12-13 Neue serinprotease-inhibitor-proteine, diese enthaltende arzneimittel, dna-sequenzen, die fuer diese proteine codieren und verfahren zur herstellung dieser proteine, arzneimittel und dna-sequenzen

Publications (2)

Publication Number Publication Date
PT92552A true PT92552A (pt) 1990-06-29
PT92552B PT92552B (pt) 1999-02-26

Family

ID=6369020

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92552A PT92552B (pt) 1988-12-13 1989-12-12 Processo de producao de sequencias de adn que codificam proteinas inibidoras da serina-protease, e de producao daquelas proteinas, de medicamentos que as contem e de vectores de expressao contendo as sequencias de adn

Country Status (13)

Country Link
EP (1) EP0373335B1 (pt)
JP (1) JP2915032B2 (pt)
AT (1) ATE161019T1 (pt)
AU (1) AU618430B2 (pt)
CA (1) CA2002047A1 (pt)
DE (2) DE3841873A1 (pt)
DK (1) DK625889A (pt)
ES (1) ES2112826T3 (pt)
HK (1) HK1005337A1 (pt)
HU (1) HUT54208A (pt)
IL (1) IL92170A0 (pt)
PT (1) PT92552B (pt)
ZA (1) ZA898395B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL316444A1 (en) * 1994-03-23 1997-01-20 Tokyo Tanabe Co Novel agent against viral diseases of respiratory tracts
DE19800363A1 (de) * 1998-01-08 1999-07-15 Forssmann Wolf Georg Prof Dr Serin-Proteinase-Inhibitoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760130A (en) * 1984-12-06 1988-07-26 Synergen Biologicals, Inc. Serine protease inhibitors and methods for isolation of same
ATE92935T1 (de) * 1984-12-06 1993-08-15 Synergen Biolog Inc Serinproteaseinhibitoren und isolierungsverfahren dazu.
DE3600571A1 (de) * 1986-01-10 1987-08-06 Gruenenthal Gmbh Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel
CA1340877C (en) * 1987-12-28 2000-01-18 Takashi Sugiyama Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology

Also Published As

Publication number Publication date
CA2002047A1 (en) 1990-06-13
AU618430B2 (en) 1991-12-19
HU896124D0 (en) 1990-02-28
DE58909824D1 (de) 1998-01-22
ES2112826T3 (es) 1998-04-16
JPH03123490A (ja) 1991-05-27
PT92552B (pt) 1999-02-26
EP0373335A3 (de) 1990-08-22
IL92170A0 (en) 1990-07-12
JP2915032B2 (ja) 1999-07-05
DK625889D0 (da) 1989-12-12
DK625889A (da) 1990-06-14
HUT54208A (en) 1991-01-28
EP0373335B1 (de) 1997-12-10
AU4602689A (en) 1990-06-21
EP0373335A2 (de) 1990-06-20
ATE161019T1 (de) 1997-12-15
ZA898395B (en) 1990-10-31
DE3841873A1 (de) 1990-06-21
HK1005337A1 (en) 1998-12-31

Similar Documents

Publication Publication Date Title
DE3685885D1 (de) Oligopeptide sowie zwischenprodukte und verfahren zu ihrer herstellung.
ATE363535T1 (de) Stabile bakterizide proteine, welche die permeabilität erhöhen und pharmazeutische zusammensetzungen, diese enthaltend
DE60320362D1 (de) Verfahren zur Herstellung von Dipeptiden
ATE264913T1 (de) Protease-resistente analoge des thrombomodulin
DE3688324D1 (de) Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel.
DE60041556D1 (de) Verfahren zur peptidherstellung
DE3682721D1 (de) Peptidaminoalkoholderivate, welche ein tetrasubstituiertes kohlenstoffatom besitzen, hemmungsstoffe von renin und proteasesaeuren, verfahren zur herstellung und pharmazeutische zusammensetzungen.
ATE408685T1 (de) Antimikrobielle peptide, abstammend von ubiquicidin
PT92552A (pt) Processo de producao de sequencias de adn que codificam proteinas inibidoras da serina-protease, e de producao daquelas proteinas, de medicamentos que as contem e de vectores de expressao contendo as sequencias de adn
ATE225805T1 (de) Hundecoronavirus s gen und verwendung davon
DE60214361D1 (de) Verfahren zur herstellung von gallensäure
ATE190493T1 (de) Verwendung von 4-(4-chlorophenyl- sulphonylcarbamoyl) benzoyl - l - valyl - l - proline 1(rs) - (1-trifluoroacetyl-2- methylpropyl)amide zur herstellung eines medikaments für die behandlung von gefässkrankheiten
ATE452903T1 (de) Modifizierte peptide und deren verwendung zur behandlung von autoimmunkrankheiten
RU95109909A (ru) Способ ингибирования ретровирусной инфекции, ингибитор протеазы, кодирующая его нуклеиновая кислота и способ рекомбинантного продуцирования серинового ингибитора
IS5210A (is) Notkun á fáliðupróteini brjóskundirstöðuefnis viðmeðhöndlun á liðagigt
DE60215206D1 (de) Enzymatisches verfahren zur enantiomeren trennung von aminosäuren
DE60224002D1 (de) Kathepsin Y Inhibitoren für die Entwicklung von Medikamenten zur Schmerzbehandlung

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19981124

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000531