PT896615E - Peptido proveniente de uma forma soluvel de acetilcolinesterase activo como modulador dos canais de calcio - Google Patents

Peptido proveniente de uma forma soluvel de acetilcolinesterase activo como modulador dos canais de calcio

Info

Publication number
PT896615E
PT896615E PT97908402T PT97908402T PT896615E PT 896615 E PT896615 E PT 896615E PT 97908402 T PT97908402 T PT 97908402T PT 97908402 T PT97908402 T PT 97908402T PT 896615 E PT896615 E PT 896615E
Authority
PT
Portugal
Prior art keywords
peptide
soleable
acetylcolinesterase
modulator
active
Prior art date
Application number
PT97908402T
Other languages
English (en)
Inventor
Susan Adele Greenfield
David John Talbutt Vaux
Original Assignee
Synaptica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synaptica Ltd filed Critical Synaptica Ltd
Publication of PT896615E publication Critical patent/PT896615E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT97908402T 1996-03-22 1997-03-21 Peptido proveniente de uma forma soluvel de acetilcolinesterase activo como modulador dos canais de calcio PT896615E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9606040.5A GB9606040D0 (en) 1996-03-22 1996-03-22 Active peptide

Publications (1)

Publication Number Publication Date
PT896615E true PT896615E (pt) 2003-01-31

Family

ID=10790837

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97908402T PT896615E (pt) 1996-03-22 1997-03-21 Peptido proveniente de uma forma soluvel de acetilcolinesterase activo como modulador dos canais de calcio

Country Status (10)

Country Link
US (1) US7018839B2 (pt)
EP (2) EP1270594A1 (pt)
JP (1) JP2000509967A (pt)
AT (1) ATE223481T1 (pt)
DE (1) DE69715181T2 (pt)
DK (1) DK0896615T3 (pt)
ES (1) ES2180948T3 (pt)
GB (1) GB9606040D0 (pt)
PT (1) PT896615E (pt)
WO (1) WO1997035962A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130225A0 (en) * 1999-05-31 2000-06-01 Yissum Res Dev Co Novel uses of antibodies against ache and peptides thereof
GB9930825D0 (en) * 1999-12-30 2000-02-16 Synaptica Limited Animal models for neurodegenerative disease
AU4432901A (en) * 2000-03-29 2001-10-08 Synaptica Limited Alpha 7 nicotinic receptor screening assays
GB0028578D0 (en) * 2000-11-23 2001-01-10 Synaptica Ltd Screening assays
KR101180896B1 (ko) 2003-05-05 2012-09-07 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 주사용 가교결합된 폴리머 제제 및 그의 용도
EP1756272A2 (en) * 2004-01-09 2007-02-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds, pharmaceutical compositions and therapeutic methods of preventing and treating diseases and disorders associated with amyloid fibril formation
CN1772766A (zh) * 2004-11-12 2006-05-17 中国科学院上海生命科学研究院 抗细胞凋亡相关乙酰胆碱酯酶单克隆抗体及其用途
GB0708646D0 (en) * 2007-05-04 2007-06-13 Enkephala Ltd Biologically active C-terminal fragment of acetylcholinesterase
GB2539161A (en) * 2014-11-26 2016-12-14 Neuro-Bio Ltd Neurodegenerative disorders
WO2016097753A1 (en) * 2014-12-19 2016-06-23 Neuro-Bio Ltd Cyclic acetylcholinesterase c-terminal peptide in the treatment or prevention of cancer or metastasis
GB2538947A (en) * 2014-12-19 2016-12-07 Neuro-Bio Ltd Cancer
GB201505239D0 (en) * 2015-03-27 2015-05-13 Neuro Bio Ltd Antibody
GB2546773B (en) * 2016-01-28 2020-06-17 Neuro Bio Ltd Cancer
CN110028550B (zh) * 2016-07-07 2022-08-05 华东理工大学 降血压肽和降血压蛋白质及其应用
CN110305224B (zh) * 2019-06-28 2021-07-13 天津科技大学 一种具有阻抗蛋白聚集功能的Aβ42修饰蛋白及其表达与纯化方法
GB2587211A (en) 2019-09-18 2021-03-24 Neuro Bio Ltd Animal model
GB202113941D0 (en) * 2021-09-29 2021-11-10 Neuro Bio Ltd Skin biomarker

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8709400D0 (en) 1987-04-21 1987-05-28 Smith A D Acetylcholinesterase
GB8927389D0 (en) * 1989-12-04 1990-01-31 Jehanli Ahmed M T Monoclonal antibodies
US5932780A (en) * 1994-02-28 1999-08-03 Yissum Research Development Company Of Hebrew University Of Jerusalem Transgenic non-human animal assay system for anti-cholinesterase substances
GB0028578D0 (en) * 2000-11-23 2001-01-10 Synaptica Ltd Screening assays

Also Published As

Publication number Publication date
ES2180948T3 (es) 2003-02-16
US7018839B2 (en) 2006-03-28
JP2000509967A (ja) 2000-08-08
EP0896615B1 (en) 2002-09-04
ATE223481T1 (de) 2002-09-15
GB9606040D0 (en) 1996-05-22
WO1997035962A1 (en) 1997-10-02
DE69715181T2 (de) 2003-04-30
DK0896615T3 (da) 2003-01-06
EP0896615A1 (en) 1999-02-17
DE69715181D1 (de) 2002-10-10
EP1270594A1 (en) 2003-01-02
US20020054870A1 (en) 2002-05-09

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