PT87461A - 1-]n-(2-alkylthio-10h-phenothiazin-10-yl)alkyl"-4-benzoylpiperidines a process for their preparation and their use as medicaments - Google Patents

1-]n-(2-alkylthio-10h-phenothiazin-10-yl)alkyl"-4-benzoylpiperidines a process for their preparation and their use as medicaments

Info

Publication number
PT87461A
PT87461A PT87461A PT8746188A PT87461A PT 87461 A PT87461 A PT 87461A PT 87461 A PT87461 A PT 87461A PT 8746188 A PT8746188 A PT 8746188A PT 87461 A PT87461 A PT 87461A
Authority
PT
Portugal
Prior art keywords
alkyl
benzoylpiperidines
phenothiazin
preparation
inclusive
Prior art date
Application number
PT87461A
Other languages
English (en)
Other versions
PT87461B (pt
Inventor
Grover Cleveland Helsley
Larry Davis
Gordon E Olsen
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT87461A publication Critical patent/PT87461A/pt
Publication of PT87461B publication Critical patent/PT87461B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
PT87461A 1987-05-13 1988-05-12 Processo para a preparacao de 1-{n-(2-alquiltio-10h-fenotiazin-10-il)alquil}-4-benzoilpiperidinas e de composicoes farmaceuticas que os contem PT87461B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/049,234 US4812456A (en) 1987-05-13 1987-05-13 1-(N-(2-alkylthio-10H-phenothiazin-10-yl)alkyl)-4-benzoylpiperidines and pharmaceutical use

Publications (2)

Publication Number Publication Date
PT87461A true PT87461A (pt) 1989-05-31
PT87461B PT87461B (pt) 1992-09-30

Family

ID=21958748

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87461A PT87461B (pt) 1987-05-13 1988-05-12 Processo para a preparacao de 1-{n-(2-alquiltio-10h-fenotiazin-10-il)alquil}-4-benzoilpiperidinas e de composicoes farmaceuticas que os contem

Country Status (8)

Country Link
US (1) US4812456A (pt)
EP (1) EP0290985B1 (pt)
JP (1) JPS63287778A (pt)
AT (1) ATE78034T1 (pt)
DE (1) DE3872593T2 (pt)
DK (1) DK259388A (pt)
GR (1) GR3005904T3 (pt)
PT (1) PT87461B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770659B2 (en) 2002-08-26 2004-08-03 Sk Corporation Benzoyl piperidine compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1216268A (fr) * 1958-04-24 1960-04-25 Rhone Poulenc Sa Nouveaux dérivés de la phénothiazine à chaîne pipéridine substituée par une fonction amide et leur préparation
US3063996A (en) * 1959-03-02 1962-11-13 Smith Kline French Lab Substituted piperidinylalkyl phenothiazines
DE1159954B (de) * 1961-11-25 1963-12-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze
GB1178623A (en) * 1966-05-10 1970-01-21 Sandoz Ltd Phenothiazine Derivatives
US4018922A (en) * 1971-05-14 1977-04-19 Roussel-Uclaf 10-(Piperidin o-alkyl)-phenothiazines
US4021552A (en) * 1975-06-27 1977-05-03 A. H. Robins Company, Incorporated 10-[ω-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES

Also Published As

Publication number Publication date
EP0290985B1 (en) 1992-07-08
DE3872593T2 (de) 1993-01-28
EP0290985A1 (en) 1988-11-17
US4812456A (en) 1989-03-14
GR3005904T3 (pt) 1993-06-07
DE3872593D1 (de) 1992-08-13
ATE78034T1 (de) 1992-07-15
DK259388D0 (da) 1988-05-11
DK259388A (da) 1988-11-14
PT87461B (pt) 1992-09-30
JPS63287778A (ja) 1988-11-24

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920310

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930930