PT87366A - Processo para a preparacao de derivados de 3-alil e 3-butenil-3-cefem e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de 3-alil e 3-butenil-3-cefem e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT87366A PT87366A PT87366A PT8736688A PT87366A PT 87366 A PT87366 A PT 87366A PT 87366 A PT87366 A PT 87366A PT 8736688 A PT8736688 A PT 8736688A PT 87366 A PT87366 A PT 87366A
- Authority
- PT
- Portugal
- Prior art keywords
- cephem
- cpd
- phosphine
- tri
- halomethyl
- Prior art date
Links
- -1 methyl 3-cephem Chemical compound 0.000 title abstract 3
- 239000003880 polar aprotic solvent Substances 0.000 title abstract 2
- 229910000080 stannane Inorganic materials 0.000 title abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 title 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 title 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 title 1
- 230000008878 coupling Effects 0.000 title 1
- 238000010168 coupling process Methods 0.000 title 1
- 238000005859 coupling reaction Methods 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 125000001183 hydrocarbyl group Chemical group 0.000 title 1
- 229910052763 palladium Inorganic materials 0.000 title 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 title 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 2
- 229920002554 vinyl polymer Polymers 0.000 abstract 2
- FZEVMBJWXHDLDB-ZCFIWIBFSA-N (6r)-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical group S1CC=CN2C(=O)C[C@H]21 FZEVMBJWXHDLDB-ZCFIWIBFSA-N 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- WXHIJDCHNDBCNY-UHFFFAOYSA-N palladium dihydride Chemical compound [PdH2] WXHIJDCHNDBCNY-UHFFFAOYSA-N 0.000 abstract 1
- KXCAEQNNTZANTK-UHFFFAOYSA-N stannane Chemical compound [SnH4] KXCAEQNNTZANTK-UHFFFAOYSA-N 0.000 abstract 1
- DLQYXUGCCKQSRJ-UHFFFAOYSA-N tris(furan-2-yl)phosphane Chemical compound C1=COC(P(C=2OC=CC=2)C=2OC=CC=2)=C1 DLQYXUGCCKQSRJ-UHFFFAOYSA-N 0.000 abstract 1
- KUCPTMZJPDVWJL-UHFFFAOYSA-N trithiophen-2-ylphosphane Chemical compound C1=CSC(P(C=2SC=CC=2)C=2SC=CC=2)=C1 KUCPTMZJPDVWJL-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT87366A PT87366B (pt) | 1988-04-29 | 1988-04-29 | Processo para a preparacao de derivados de 3-alil e 3-butenil-3-cefem e de composicoes farmaceuticas que os contem |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT87366A PT87366B (pt) | 1988-04-29 | 1988-04-29 | Processo para a preparacao de derivados de 3-alil e 3-butenil-3-cefem e de composicoes farmaceuticas que os contem |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87366A true PT87366A (pt) | 1989-11-10 |
| PT87366B PT87366B (pt) | 1994-05-31 |
Family
ID=20084216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87366A PT87366B (pt) | 1988-04-29 | 1988-04-29 | Processo para a preparacao de derivados de 3-alil e 3-butenil-3-cefem e de composicoes farmaceuticas que os contem |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT87366B (pt) |
-
1988
- 1988-04-29 PT PT87366A patent/PT87366B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT87366B (pt) | 1994-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19931108 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20080508 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20081108 |