PT87139A - Process for the preparation of dopamina-beta-hydroxylase inhibitors of their intermediaries and of pharmaceutical compounds - Google Patents

Process for the preparation of dopamina-beta-hydroxylase inhibitors of their intermediaries and of pharmaceutical compounds

Info

Publication number
PT87139A
PT87139A PT87139A PT8713988A PT87139A PT 87139 A PT87139 A PT 87139A PT 87139 A PT87139 A PT 87139A PT 8713988 A PT8713988 A PT 8713988A PT 87139 A PT87139 A PT 87139A
Authority
PT
Portugal
Prior art keywords
intermediaries
dopamine
beta
preparation
pharmaceutical compounds
Prior art date
Application number
PT87139A
Other languages
English (en)
Other versions
PT87139B (pt
Inventor
Lawrence Ivan Kruse
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of PT87139A publication Critical patent/PT87139A/pt
Publication of PT87139B publication Critical patent/PT87139B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
PT87139A 1987-03-30 1988-03-30 Processo de preparacao de inibidores da dopamina-b-hidroxilase, dos seus intermediarios e de composicoes farmaceuticas PT87139B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3173587A 1987-03-30 1987-03-30

Publications (2)

Publication Number Publication Date
PT87139A true PT87139A (pt) 1988-04-01
PT87139B PT87139B (pt) 1992-07-31

Family

ID=21861108

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87139A PT87139B (pt) 1987-03-30 1988-03-30 Processo de preparacao de inibidores da dopamina-b-hidroxilase, dos seus intermediarios e de composicoes farmaceuticas

Country Status (6)

Country Link
EP (1) EP0285356A3 (pt)
JP (1) JPS63258417A (pt)
AU (1) AU1400988A (pt)
DK (1) DK178788A (pt)
PT (1) PT87139B (pt)
ZA (1) ZA882275B (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003732B1 (en) * 1978-02-01 1983-10-19 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
JP2581556B2 (ja) * 1986-05-06 1997-02-12 メレルダウファーマスーティカルズ インコーポレーテッド 新規なドパミンベ−タヒドロキシラ−ゼ抑制剤

Also Published As

Publication number Publication date
DK178788D0 (da) 1988-03-30
AU1400988A (en) 1988-09-29
EP0285356A2 (en) 1988-10-05
JPS63258417A (ja) 1988-10-25
EP0285356A3 (en) 1989-05-31
PT87139B (pt) 1992-07-31
DK178788A (da) 1988-10-01
ZA882275B (en) 1989-02-22

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920110

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940731