PT83126B - Inalador - Google Patents
Inalador Download PDFInfo
- Publication number
- PT83126B PT83126B PT83126A PT8312686A PT83126B PT 83126 B PT83126 B PT 83126B PT 83126 A PT83126 A PT 83126A PT 8312686 A PT8312686 A PT 8312686A PT 83126 B PT83126 B PT 83126B
- Authority
- PT
- Portugal
- Prior art keywords
- passage
- air
- inhaler according
- film
- sphere
- Prior art date
Links
- 239000000126 substance Substances 0.000 claims abstract description 33
- 239000007787 solid Substances 0.000 claims abstract description 23
- 239000013543 active substance Substances 0.000 claims description 38
- 239000002245 particle Substances 0.000 claims description 26
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 claims description 22
- 229960002052 salbutamol Drugs 0.000 claims description 22
- 230000015572 biosynthetic process Effects 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 12
- 229910052782 aluminium Inorganic materials 0.000 claims description 8
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 5
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 claims description 4
- 229950000210 beclometasone dipropionate Drugs 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 4
- 239000000758 substrate Substances 0.000 claims description 4
- 239000011888 foil Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 29
- 239000000203 mixture Substances 0.000 description 23
- 239000000463 material Substances 0.000 description 16
- 239000012153 distilled water Substances 0.000 description 10
- 239000000243 solution Substances 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 239000011324 bead Substances 0.000 description 7
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
- 239000002775 capsule Substances 0.000 description 6
- 229920003023 plastic Polymers 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 238000000576 coating method Methods 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 239000006185 dispersion Substances 0.000 description 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 3
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 3
- 239000011343 solid material Substances 0.000 description 3
- 235000010447 xylitol Nutrition 0.000 description 3
- 239000000811 xylitol Substances 0.000 description 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 3
- 229960002675 xylitol Drugs 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000013467 fragmentation Methods 0.000 description 2
- 238000006062 fragmentation reaction Methods 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- 239000004014 plasticizer Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000012265 solid product Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 1
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 238000009954 braiding Methods 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 229960000265 cromoglicic acid Drugs 0.000 description 1
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical compound O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000009474 immediate action Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000011169 microbiological contamination Methods 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- -1 polytetrafluoroethylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229960000195 terbutaline Drugs 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- External Artificial Organs (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Weting (AREA)
- Luminescent Compositions (AREA)
- Organic Insulating Materials (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0227285A AT384552B (de) | 1985-08-01 | 1985-08-01 | Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT83126A PT83126A (pt) | 1987-02-27 |
| PT83126B true PT83126B (pt) | 1993-05-31 |
Family
ID=3531262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT83126A PT83126B (pt) | 1985-08-01 | 1986-08-01 | Inalador |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4841964A (OSRAM) |
| EP (1) | EP0215559B1 (OSRAM) |
| JP (1) | JPS6234573A (OSRAM) |
| AT (2) | AT384552B (OSRAM) |
| AU (1) | AU6075986A (OSRAM) |
| CA (1) | CA1270711A (OSRAM) |
| DE (1) | DE3668783D1 (OSRAM) |
| DK (1) | DK162740C (OSRAM) |
| FI (1) | FI89331C (OSRAM) |
| GB (1) | GB2179260A (OSRAM) |
| GR (1) | GR861996B (OSRAM) |
| IE (1) | IE59027B1 (OSRAM) |
| NZ (1) | NZ217045A (OSRAM) |
| PT (1) | PT83126B (OSRAM) |
Families Citing this family (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
| DE407028T1 (de) * | 1989-05-31 | 1994-03-17 | Fisons Plc | Medikament und Inhalationsvorrichtung dafür. |
| FI84698C (fi) * | 1989-06-16 | 1992-01-10 | Huhtamaeki Oy | Anordning foer finfoerdelning av agglomerat av en enkeldos av ett laekemedelpreparat i pulverform. |
| US5239991A (en) * | 1989-06-21 | 1993-08-31 | Fisons Plc | Disposable powder medicament inhalation device with peel-off cover |
| GB8914223D0 (en) * | 1989-06-21 | 1989-08-09 | Fisons Plc | Medicament container |
| US6048857A (en) * | 1989-10-17 | 2000-04-11 | Ellinwood, Jr.; Everett H. | Dosing method of administering medicaments via inhalation administration |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| SK280968B6 (sk) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Balenie medikamentu na použite v inhalačnom prístroji |
| TW197380B (OSRAM) | 1990-03-02 | 1993-01-01 | Glaxo Group Ltd | |
| JPH0439231U (OSRAM) * | 1990-07-30 | 1992-04-02 | ||
| SE9002895D0 (sv) * | 1990-09-12 | 1990-09-12 | Astra Ab | Inhalation devices for dispensing powders i |
| JPH068206A (ja) * | 1990-12-05 | 1994-01-18 | Eidai Co Ltd | 化粧板 |
| US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
| JPH0521027U (ja) * | 1991-08-30 | 1993-03-19 | 永大産業株式会社 | 化粧複合床板 |
| DE69219252T2 (de) * | 1991-09-04 | 1997-08-07 | Koyo Seiko Co., Ltd., Osaka | Ölbehälter |
| US5476093A (en) * | 1992-02-14 | 1995-12-19 | Huhtamaki Oy | Device for more effective pulverization of a powdered inhalation medicament |
| EP0558879B1 (en) * | 1992-03-04 | 1997-05-14 | Astra Aktiebolag | Disposable inhaler |
| ES2118234T3 (es) * | 1992-05-29 | 1998-09-16 | Ggu Gesundheits Umweltforsch | Dispositivo para generar particulas inhalables de sustancias activas. |
| EP0665759B1 (en) * | 1992-10-19 | 1998-12-23 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| AT398277B (de) * | 1992-12-11 | 1994-11-25 | Hurka Wilhelm | Inhalationsgerät |
| US5829434A (en) * | 1992-12-18 | 1998-11-03 | Schering Corporation | Inhaler for powdered medications |
| IL108780A (en) * | 1993-02-27 | 1999-06-20 | Fisons Plc | Inhalation device |
| FI954098A7 (fi) * | 1993-03-03 | 1995-09-01 | Tenax Corp | Kuivajauheen inhalaattorin lääkeaineen kantolaite |
| GB9306703D0 (en) * | 1993-03-31 | 1993-05-26 | Fisons Plc | Inhalation device |
| SE9302550D0 (sv) * | 1993-07-30 | 1993-07-30 | Ernst Hoerlin | Powder inhaler |
| US5524613A (en) * | 1993-08-25 | 1996-06-11 | Habley Medical Technology Corporation | Controlled multi-pharmaceutical inhaler |
| US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
| US5388573A (en) * | 1993-12-02 | 1995-02-14 | Tenax Corporation | Dry powder inhalator medicament carrier |
| US5647347A (en) * | 1994-10-21 | 1997-07-15 | Glaxo Wellcome Inc. | Medicament carrier for dry powder inhalator |
| US5503869A (en) * | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
| US5669378A (en) * | 1995-12-21 | 1997-09-23 | Pera; Ivo | Inhaling device |
| USD381416S (en) * | 1996-02-08 | 1997-07-22 | Astra Aktiebolag | Unit dose inhaler |
| GB9626233D0 (en) * | 1996-12-18 | 1997-02-05 | Chawla Brinda P S | Medicament packaging and deliveery device |
| TW469832U (en) * | 1997-03-14 | 2001-12-21 | Astra Ab | Inhalation device |
| SE9700936D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Inhalation device |
| SE9700937D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler I |
| CA2212430A1 (en) | 1997-08-07 | 1999-02-07 | George Volgyesi | Inhalation device |
| US6073629A (en) * | 1997-09-25 | 2000-06-13 | Norton Healthcare Ltd. | Inhaler spacer |
| GB9720283D0 (en) * | 1997-09-25 | 1997-11-26 | Norton Healthcare Ltd | Inhaler spacer |
| JP2000217917A (ja) * | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| GB9929486D0 (en) | 1999-12-15 | 2000-02-09 | Glaxo Group Ltd | Inhalation delivery apparatus and method |
| US6427688B1 (en) * | 2000-02-01 | 2002-08-06 | Dura Pharmaceuticals, Icn. | Dry powder inhaler |
| US7069929B2 (en) * | 2000-02-01 | 2006-07-04 | Quadrant Technologies Limited | Dry powder inhaler |
| AU2001283546A1 (en) | 2000-08-14 | 2002-02-25 | Advanced Inhalation Research, Inc. | Inhalation device and method |
| US6766799B2 (en) * | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| EP1392383A2 (en) * | 2001-05-10 | 2004-03-03 | Vectura Delivery Devices Limited | Inhalers |
| GB0130055D0 (en) * | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
| ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
| ATE477193T1 (de) * | 2003-03-15 | 2010-08-15 | Brin Tech Internat Ltd | Verpackung für arzneimittel |
| DE10356925B4 (de) * | 2003-12-05 | 2006-05-11 | Lts Lohmann Therapie-Systeme Ag | Inhalator für basische pharmazeutische Wirkstoffe sowie Verfahren für dessen Herstellung |
| DE602005024413D1 (de) | 2004-08-20 | 2010-12-09 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| CN104436170B (zh) | 2004-08-23 | 2018-02-23 | 曼金德公司 | 用于药物输送的二酮哌嗪盐 |
| IL175664A0 (en) * | 2006-05-16 | 2006-09-05 | Aespira Ltd | Dry-powder inhaler |
| US8763605B2 (en) | 2005-07-20 | 2014-07-01 | Manta Devices, Llc | Inhalation device |
| JP5167133B2 (ja) | 2005-09-14 | 2013-03-21 | マンカインド コーポレイション | 結晶性微粒子表面に対する活性薬剤の親和性の増大に基づく薬物処方の方法 |
| GB0520794D0 (en) | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
| US7832397B2 (en) * | 2005-12-28 | 2010-11-16 | Philip Morris Usa Inc. | Aerosol powder delivery device |
| MX2008010721A (es) | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
| GB2448838B (en) * | 2006-05-26 | 2009-02-11 | Consort Medical Plc | Improvements in or relating to dispensing apparatus |
| GB0610541D0 (en) * | 2006-05-26 | 2006-07-05 | Bespak Plc | Improvements in or relating to dispensing apparatus |
| GB0611656D0 (en) | 2006-06-13 | 2006-07-19 | Cambridge Consultants | Dry powder inhalers |
| WO2008156586A2 (en) * | 2007-06-12 | 2008-12-24 | Alkermes, Inc. | Inhalation device for powdered substances |
| US11224704B2 (en) | 2007-07-06 | 2022-01-18 | Manta Devices, Llc | Dose delivery device for inhalation |
| EP2898914B1 (en) * | 2007-07-06 | 2018-06-20 | Manta Devices, LLC | Inhalation devices for storing and delivering medicament |
| PT2254629E (pt) * | 2008-03-27 | 2016-03-02 | Mannkind Corp | Um sistema de inalação de pó seco |
| JP5421362B2 (ja) | 2008-06-13 | 2014-02-19 | マンカインド コーポレイション | 薬物送達用の乾燥粉末吸入器およびシステム |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| RU2470681C2 (ru) | 2008-06-20 | 2012-12-27 | Маннкайнд Корпорейшн | Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени |
| FR2933619B1 (fr) * | 2008-07-11 | 2012-03-30 | Valois Sas | Dispositif d'inhalation de poudre |
| WO2010011329A2 (en) * | 2008-07-23 | 2010-01-28 | Map Pharmaceuticals, Inc. | The delivery of powdered drug via inhalation |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| US8550074B2 (en) | 2009-01-15 | 2013-10-08 | Manta Devices, Llc | Delivery device and related methods |
| EP2405963B1 (en) | 2009-03-11 | 2013-11-06 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| GB0914738D0 (en) * | 2009-08-24 | 2009-09-30 | Cambridge Consultants | Inhalers |
| EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
| US9492625B2 (en) | 2009-11-12 | 2016-11-15 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
| WO2011116293A2 (en) | 2010-03-19 | 2011-09-22 | Manta Devices, Llc | Delivery device and related methods |
| JP6385673B2 (ja) | 2010-06-21 | 2018-09-05 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
| WO2012078804A1 (en) | 2010-12-07 | 2012-06-14 | Respira Therapeutics, Inc. | Dry powder inhaler |
| WO2012135765A2 (en) | 2011-04-01 | 2012-10-04 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| US11103659B2 (en) | 2011-07-06 | 2021-08-31 | Manta Devices, Llc | Delivery device and related methods |
| CN106730186B (zh) * | 2011-09-07 | 2020-06-09 | 康森特里克斯药物公司 | 干粉吸入装置 |
| IN2014DN03093A (OSRAM) | 2011-10-24 | 2015-05-15 | Mannkind Corp | |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| US9649454B2 (en) | 2012-05-03 | 2017-05-16 | Manta Devices, Llc | Delivery device and related methods |
| AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
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| ES2754388T3 (es) | 2013-03-15 | 2020-04-17 | Mannkind Corp | Composiciones y métodos de dicetopiperazina microcristalina |
| EP3003905B1 (en) * | 2013-06-03 | 2020-05-13 | Essentra Filter Products Development Co. Pte. Ltd | Dispenser for particulate material, product |
| AU2014290438B2 (en) | 2013-07-18 | 2019-11-07 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
| EP3110484A4 (en) * | 2014-02-21 | 2018-02-14 | Respira Therapeutics, Inc. | Powder inhaler, system and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US11147936B2 (en) | 2014-05-02 | 2021-10-19 | Manta Devices, Llc | Dose delivery device with cover connected to dose chamber seal |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| EP3244952A4 (en) * | 2015-01-14 | 2018-11-14 | Respira Therapeutics, Inc. | Powder dispersion methods and devices |
| EP3181172A1 (en) * | 2015-12-18 | 2017-06-21 | University of Limerick | A positive exhalation pressure device |
| EP3600504B1 (en) | 2017-03-28 | 2023-07-12 | Concentrx Pharmaceuticals, Inc. | Device for delivering dry powder medicaments |
| DE102017006763A1 (de) * | 2017-07-18 | 2019-01-24 | Klaus Dieter Beller | Einzeldosis-Pulverinhalator |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE483136A (OSRAM) * | 1947-09-04 | 1942-06-30 | ||
| US2534636A (en) * | 1949-02-12 | 1950-12-19 | American Cyanamid Co | Powder dispenser |
| US2816549A (en) * | 1956-11-16 | 1957-12-17 | Isaac E Webster | Dispensing device |
| US3809084A (en) * | 1970-02-16 | 1974-05-07 | American Cyanamid Co | Pressurized portable dispenser |
| US4069819A (en) * | 1973-04-13 | 1978-01-24 | Societa Farmaceutici S.P.A. | Inhalation device |
| EP0041783B1 (en) * | 1980-06-06 | 1984-12-05 | FISONS plc | Inhalation device for powdered medicaments |
-
1985
- 1985-08-01 AT AT0227285A patent/AT384552B/de not_active IP Right Cessation
-
1986
- 1986-07-29 GR GR861996A patent/GR861996B/el unknown
- 1986-07-31 CA CA000515100A patent/CA1270711A/en not_active Expired
- 1986-07-31 AU AU60759/86A patent/AU6075986A/en not_active Abandoned
- 1986-07-31 IE IE206086A patent/IE59027B1/en not_active IP Right Cessation
- 1986-07-31 GB GB08618762A patent/GB2179260A/en not_active Withdrawn
- 1986-07-31 DK DK365986A patent/DK162740C/da not_active IP Right Cessation
- 1986-07-31 EP EP86305887A patent/EP0215559B1/en not_active Expired
- 1986-07-31 FI FI863127A patent/FI89331C/fi not_active IP Right Cessation
- 1986-07-31 AT AT86305887T patent/ATE50147T1/de not_active IP Right Cessation
- 1986-07-31 DE DE8686305887T patent/DE3668783D1/de not_active Expired - Lifetime
- 1986-07-31 NZ NZ217045A patent/NZ217045A/xx unknown
- 1986-07-31 US US06/892,197 patent/US4841964A/en not_active Expired - Fee Related
- 1986-08-01 PT PT83126A patent/PT83126B/pt not_active IP Right Cessation
- 1986-08-01 JP JP61180270A patent/JPS6234573A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2179260A (en) | 1987-03-04 |
| AU6075986A (en) | 1987-02-05 |
| FI863127L (fi) | 1987-02-02 |
| FI89331C (fi) | 1993-09-27 |
| DE3668783D1 (de) | 1990-03-15 |
| GB8618762D0 (en) | 1986-09-10 |
| AT384552B (de) | 1987-12-10 |
| GR861996B (en) | 1986-11-24 |
| ATE50147T1 (de) | 1990-02-15 |
| PT83126A (pt) | 1987-02-27 |
| DK162740B (da) | 1991-12-09 |
| IE862060L (en) | 1987-02-01 |
| CA1270711A (en) | 1990-06-26 |
| DK365986A (da) | 1987-02-02 |
| ATA227285A (de) | 1987-05-15 |
| US4841964A (en) | 1989-06-27 |
| JPH0234620B2 (OSRAM) | 1990-08-06 |
| JPS6234573A (ja) | 1987-02-14 |
| FI89331B (fi) | 1993-06-15 |
| EP0215559A1 (en) | 1987-03-25 |
| DK365986D0 (da) | 1986-07-31 |
| FI863127A0 (fi) | 1986-07-31 |
| NZ217045A (en) | 1989-04-26 |
| EP0215559B1 (en) | 1990-02-07 |
| IE59027B1 (en) | 1993-12-15 |
| DK162740C (da) | 1992-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19921120 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19940531 |