PT82643B - Processo para a preparacao de hexa-hidro-arilquinolizinas substituidas - Google Patents

Processo para a preparacao de hexa-hidro-arilquinolizinas substituidas

Info

Publication number
PT82643B
PT82643B PT82643A PT8264386A PT82643B PT 82643 B PT82643 B PT 82643B PT 82643 A PT82643 A PT 82643A PT 8264386 A PT8264386 A PT 8264386A PT 82643 B PT82643 B PT 82643B
Authority
PT
Portugal
Prior art keywords
arillykinolines
hexa
hydro
replaced
preparation
Prior art date
Application number
PT82643A
Other languages
English (en)
Other versions
PT82643A (en
Inventor
John J Baldwin
Joel R Huff
Steven D Young
Joseph P Vacca
Jane De Solms
James P Guare Jr
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT82643A publication Critical patent/PT82643A/pt
Publication of PT82643B publication Critical patent/PT82643B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT82643A 1985-06-03 1986-05-26 Processo para a preparacao de hexa-hidro-arilquinolizinas substituidas PT82643B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74060985A 1985-06-03 1985-06-03

Publications (2)

Publication Number Publication Date
PT82643A PT82643A (en) 1986-06-01
PT82643B true PT82643B (pt) 1988-03-03

Family

ID=24977288

Family Applications (1)

Application Number Title Priority Date Filing Date
PT82643A PT82643B (pt) 1985-06-03 1986-05-26 Processo para a preparacao de hexa-hidro-arilquinolizinas substituidas

Country Status (11)

Country Link
EP (1) EP0204254A3 (pt)
JP (1) JPS6236380A (pt)
KR (1) KR900004588B1 (pt)
AU (1) AU576962B2 (pt)
DK (1) DK258086A (pt)
ES (1) ES8707729A1 (pt)
GR (1) GR861403B (pt)
IL (1) IL78918A (pt)
NZ (1) NZ216283A (pt)
PT (1) PT82643B (pt)
ZA (1) ZA864096B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ221485A (en) * 1986-08-28 1991-04-26 Merck & Co Inc Hexahydroarylquinolizine derivatives and pharmaceutical compositions
US4831035A (en) * 1986-08-28 1989-05-16 Merck & Co., Inc. Substituted hexahydroarylquinolizines
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
EP1490361B1 (en) 2002-04-03 2007-10-03 Orion Corporation Polycyclic compounds as potent alpha2-adrenoceptor antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1524953A (fr) * 1962-03-26 1968-05-17 Konink Pharmaceutische Fabrike Procédé de préparation des dérivés de la quinolizine

Also Published As

Publication number Publication date
ES8707729A1 (es) 1987-08-16
DK258086A (da) 1987-02-20
KR870000331A (ko) 1987-02-17
JPS6236380A (ja) 1987-02-17
NZ216283A (en) 1989-10-27
ES555670A0 (es) 1987-08-16
AU5826086A (en) 1986-12-11
IL78918A (en) 1990-06-10
ZA864096B (en) 1987-01-28
AU576962B2 (en) 1988-09-08
IL78918A0 (en) 1986-09-30
KR900004588B1 (ko) 1990-06-30
PT82643A (en) 1986-06-01
EP0204254A2 (en) 1986-12-10
EP0204254A3 (en) 1988-03-02
GR861403B (en) 1986-09-26
DK258086D0 (da) 1986-06-02

Similar Documents

Publication Publication Date Title
PT83179B (pt) Processo para a preparacao de carbinois aril-piperidinicos
PT81859B (pt) Processo para a preparacao de derivados de tiazolidinodionas
PT83504B (pt) Processo para a preparacao de acrilamidas substituidas
PT83085B (pt) Processo para a preparacao de eteres de fenilo
BR8605084A (pt) Processo para a preparacao de diaminocompostos aromaticos
PT83152B (pt) Processo para a preparacao de compostos di-t-butilfenoicos
PT82062B (pt) Processo para a preparacao de compostos piridinilimidazolidinona
BR8601962A (pt) Processo para a preparacao de compostos
PT83344A (pt) Processo para a preparacao de ypsilon-carbolinas antipsicoticas
BR8707028A (pt) Processo para a preparacao de mercaptometilfenois
PT82678B (pt) Processo para a preparacao de compostos de cinolina
PT83802B (pt) Processo para a fabricacao de um condimento
PT84072B (pt) Processo para a preparacao de esteroides aminoglicosidicos
PT83074B (pt) Processo para a preparacao de produtos de solvatacao de 3-propenil-cefalosporina
PT82400B (pt) Processo para a preparacao de benziltriazoles fluorados
BR8501588A (pt) Processo para a preparacao de poliisocianatos
PT82383B (pt) Processo para a preparacao de epipodofilotoxina e compostos afins
PT89056A (pt) Processo para a preparacao de hidroxilaminas substituidas
BR8505989A (pt) Processo para a preparacao de amino-4-difenilaminas
BR8502305A (pt) Processo para a preparacao de organopol issiloxanas organofuncionais
PT82245B (pt) Processo para a preparacao de 2-amino-6-cloropurina
BR8706408A (pt) Processo para a preparacao de aldeidos
BR8501134A (pt) Processo para a preparacao de gliciditeres
PT83154B (pt) Processo para a preparacao de quinolizino-sulfonamidas
BR8602094A (pt) Processo para a preparacao de benzotiazolsulfenamidas

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920330