PT80824B - Process for the preparation of phenylquinoline derivatives and of pharmaceutical compositions containing the same - Google Patents
Process for the preparation of phenylquinoline derivatives and of pharmaceutical compositions containing the sameInfo
- Publication number
- PT80824B PT80824B PT80824A PT8082485A PT80824B PT 80824 B PT80824 B PT 80824B PT 80824 A PT80824 A PT 80824A PT 8082485 A PT8082485 A PT 8082485A PT 80824 B PT80824 B PT 80824B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- same
- pharmaceutical compositions
- compositions containing
- phenylquinoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/631,971 US4560692A (en) | 1984-07-18 | 1984-07-18 | 4-Piperidino-2-phenylquinolines |
Publications (2)
Publication Number | Publication Date |
---|---|
PT80824A PT80824A (en) | 1985-08-01 |
PT80824B true PT80824B (en) | 1987-05-27 |
Family
ID=24533539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT80824A PT80824B (en) | 1984-07-18 | 1985-07-17 | Process for the preparation of phenylquinoline derivatives and of pharmaceutical compositions containing the same |
Country Status (18)
Country | Link |
---|---|
US (1) | US4560692A ( ) |
EP (1) | EP0168812A1 ( ) |
JP (1) | JPS6136283A ( ) |
KR (1) | KR860001097A ( ) |
AU (1) | AU4508085A ( ) |
CS (1) | CS252830B2 ( ) |
DK (1) | DK326085A ( ) |
ES (2) | ES8609302A1 ( ) |
FI (1) | FI852790L ( ) |
GR (1) | GR851761B ( ) |
HU (1) | HU194207B ( ) |
IL (1) | IL75825A0 ( ) |
MC (1) | MC1691A1 ( ) |
NO (1) | NO852854L ( ) |
PH (1) | PH21022A ( ) |
PT (1) | PT80824B ( ) |
ZA (1) | ZA854718B ( ) |
ZW (1) | ZW11785A1 ( ) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3800868A1 (de) * | 1988-01-14 | 1989-07-27 | Thomae Gmbh Dr K | Mittel zur behandlung von bradycardien und bradyarrhythmien |
US5304554A (en) * | 1990-04-27 | 1994-04-19 | Emory University | 4-[(alkyl or dialkyl)amino]quinolines and their method of preparation |
US6103903A (en) | 1998-02-26 | 2000-08-15 | Neurogen Corporation | 4-(4-piperidylmethyhlamino) substituted heteroaryl fused pyridines: GABA brain receptor ligands |
AU2793199A (en) * | 1998-02-26 | 1999-09-15 | Neurogen Corporation | 2-(het-)aryl-4-(cyclic amino substituted) heteroaryl fused pyridine derivatives,their preparation and their use as (ant-)agonists for gaba (a) brain receptors |
US6297256B1 (en) * | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
US6440995B1 (en) | 1999-10-01 | 2002-08-27 | Hoffman-La Roche Inc. | Quinolin-4-yl derivatives |
US6339093B1 (en) * | 1999-10-08 | 2002-01-15 | Hoffmann-La Roche Inc. | Isoquinoline derivatives |
DE60144322D1 (de) | 2000-04-27 | 2011-05-12 | Astellas Pharma Inc | Kondensierte heteroarylderivate |
US7825389B2 (en) | 2007-12-04 | 2010-11-02 | Tel Epion Inc. | Method and apparatus for controlling a gas cluster ion beam formed from a gas mixture |
EP2976333B1 (en) * | 2013-03-18 | 2018-08-08 | Genoscience Pharma SAS | Quinolines derivatives as novel anticancer agents |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1510009A (fr) * | 1966-12-02 | 1968-01-19 | Dérivés de l'amino-4 quinoléine | |
PT66682B (pt) * | 1976-06-18 | 1978-11-15 | Ind Biolog Francaise | /(quinolyl-4)-propyl-1/-4 piperidines leur preparation et leur utilisation comme medicaments /(quinolyl-4)-propyl/-4 piperidines leur preparation et leur utilisation comme medicaments |
FR2485014A1 (fr) * | 1980-06-20 | 1981-12-24 | Pharmindustrie | Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments |
HU190796B (en) * | 1981-06-12 | 1986-11-28 | Roussel Uclaf,Fr | Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives |
-
1984
- 1984-07-18 US US06/631,971 patent/US4560692A/en not_active Expired - Fee Related
-
1985
- 1985-06-17 MC MC851783A patent/MC1691A1/xx unknown
- 1985-06-21 ZA ZA854718A patent/ZA854718B/xx unknown
- 1985-07-16 EP EP85108885A patent/EP0168812A1/de not_active Withdrawn
- 1985-07-16 IL IL75825A patent/IL75825A0/xx unknown
- 1985-07-16 CS CS855274A patent/CS252830B2/cs unknown
- 1985-07-16 GR GR851761A patent/GR851761B/el unknown
- 1985-07-16 PH PH32528A patent/PH21022A/en unknown
- 1985-07-16 ZW ZW117/85A patent/ZW11785A1/xx unknown
- 1985-07-16 FI FI852790A patent/FI852790L/fi not_active Application Discontinuation
- 1985-07-17 HU HU852742A patent/HU194207B/hu unknown
- 1985-07-17 PT PT80824A patent/PT80824B/pt unknown
- 1985-07-17 JP JP15617185A patent/JPS6136283A/ja active Pending
- 1985-07-17 DK DK326085A patent/DK326085A/da not_active Application Discontinuation
- 1985-07-17 NO NO852854A patent/NO852854L/no unknown
- 1985-07-17 AU AU45080/85A patent/AU4508085A/en not_active Abandoned
- 1985-07-17 ES ES545298A patent/ES8609302A1/es not_active Expired
- 1985-07-18 KR KR1019850005110A patent/KR860001097A/ko not_active Application Discontinuation
-
1986
- 1986-02-17 ES ES552402A patent/ES8705421A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PH21022A (en) | 1987-06-30 |
ES8609302A1 (es) | 1986-09-01 |
ZW11785A1 (en) | 1986-02-12 |
DK326085D0 (da) | 1985-07-17 |
NO852854L (no) | 1986-01-20 |
ES8705421A1 (es) | 1987-05-01 |
KR860001097A (ko) | 1986-02-22 |
ES552402A0 (es) | 1987-05-01 |
ES545298A0 (es) | 1986-09-01 |
FI852790A0 (fi) | 1985-07-16 |
DK326085A (da) | 1986-01-19 |
CS252830B2 (en) | 1987-10-15 |
EP0168812A1 (de) | 1986-01-22 |
AU4508085A (en) | 1986-01-23 |
HUT38333A (en) | 1986-05-28 |
GR851761B ( ) | 1985-11-26 |
PT80824A (en) | 1985-08-01 |
IL75825A0 (en) | 1985-11-29 |
CS527485A2 (en) | 1987-03-12 |
JPS6136283A (ja) | 1986-02-20 |
US4560692A (en) | 1985-12-24 |
FI852790L (fi) | 1986-01-19 |
HU194207B (en) | 1988-01-28 |
ZA854718B (en) | 1986-03-26 |
MC1691A1 (fr) | 1986-07-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT81746A (en) | Process for the preparation of peptide-aldehydes and of pharmaceutical compositions containing them | |
PT81015B (en) | Process for the preparation of piridazo-diazocine derivatives and pharmaceutical compositions therewith | |
PT81007A (en) | Process for the preparation of analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives and of pharmaceutical compositions containing the same | |
PT84936A (en) | Process for the preparation of tetrahydronaphthaline and indanederivatives and of pharmaceutical compositions containing the same | |
PT86365A (en) | Process for the preparation of pyridazodiazepine derivatives and of pharmaceutical compositions containing the same | |
PT86516A (en) | Process for the preparation of heteroaryl-3-oxo-propani-nitrile derivatives and of pharmaceutical compositions containing the same | |
PT76809A (en) | Process for preparing 1-sulfo-2-oxoazetidine derivatives and of pharmaceutical compositions containing the same | |
EG17710A (en) | Process for the preparation isosilybin-free silbinin and pharmaceutical compositions containing them | |
PT80246A (en) | Process for the preparation of novel cephalosporin derivatives and of pharmaceutical compositions containing the same | |
PT82984A (en) | Process for the preparation of poly-4-aminopyrrole-2-carboxamido derivatives and of pharmaceutical compositions containing the same | |
PT86407A (en) | Process for the preparation of new alkanesulfonanilide derivatives and pharmaceutical compositions comprising the same | |
PT81502A (en) | Process for the preparation of cholecalciferol derivatives and of pharmaceutical compositions containing the same | |
PT84358A (en) | Process for the preparation of naphthothiazepinones and of pharmaceutical compositions containing the same | |
PT81431A (en) | Process for the preparation of tricyclic piridine derivatives and of pharmaceutical compositions containing the same | |
PT80794A (en) | Process for the preparation of novel isoindolinyl-alkyl-piperazines and of pharmaceutical compositions containing the same | |
PT83188A (en) | Process for the preparation of benzimidazole derivatives and of pharmaceutical compositions containing the same | |
PT79858A (en) | Process for the preparation of azolyl-aryl-alcanol and pharmaceutical compositions therewith | |
PT80824B (en) | Process for the preparation of phenylquinoline derivatives and of pharmaceutical compositions containing the same | |
PT78549A (en) | Process for preparing pyrimidone derivatives and of pharmaceutical compositions containing the same | |
PT82772A (en) | Process for the preparation of novel glycerol derivatives and of pharmaceutical compositions containing the same | |
PT76870B (en) | Process for the preparation of 1,4-dihydropiridine derivatives and pharmaceutical compositions containing them | |
PT82464A (en) | Process for the preparation of novel benzisoselenazolonyl derivatives and of pharmaceutical compositions containing the same | |
PT79199B (en) | Process for preparing 3-indolecarboxamide derivatives and of pharmaceutical compositions containing the same | |
PT80315B (en) | Process for the preparation of imidazole derivatives and of pharmaceutical compositions containing the same | |
PT81083A (en) | Process for the preparation of substituted 7-oxomitosanes and of pharmaceutical compositions containing the same |