PT78892A - Gegen denaturierung bestaendige waessrige proteinloesungen verfahren zu ihrer herstellung und ihre verwendung - Google Patents

Gegen denaturierung bestaendige waessrige proteinloesungen verfahren zu ihrer herstellung und ihre verwendung

Info

Publication number
PT78892A
PT78892A PT78892A PT7889284A PT78892A PT 78892 A PT78892 A PT 78892A PT 78892 A PT78892 A PT 78892A PT 7889284 A PT7889284 A PT 7889284A PT 78892 A PT78892 A PT 78892A
Authority
PT
Portugal
Prior art keywords
denaturing
preparation
waesser
formula
protein solutions
Prior art date
Application number
PT78892A
Other languages
German (de)
English (en)
Portuguese (pt)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT78892A publication Critical patent/PT78892A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
PT78892A 1983-07-13 1984-07-12 Gegen denaturierung bestaendige waessrige proteinloesungen verfahren zu ihrer herstellung und ihre verwendung PT78892A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833325223 DE3325223A1 (de) 1983-07-13 1983-07-13 Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
PT78892A true PT78892A (de) 1984-08-01

Family

ID=6203842

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78892A PT78892A (de) 1983-07-13 1984-07-12 Gegen denaturierung bestaendige waessrige proteinloesungen verfahren zu ihrer herstellung und ihre verwendung

Country Status (15)

Country Link
US (1) US4637834A (enExample)
EP (1) EP0131864B1 (enExample)
JP (1) JPS6038398A (enExample)
KR (1) KR920002934B1 (enExample)
AT (1) ATE56876T1 (enExample)
AU (1) AU579106B2 (enExample)
DE (2) DE3325223A1 (enExample)
DK (1) DK168030B1 (enExample)
ES (2) ES8600319A1 (enExample)
FI (1) FI80276C (enExample)
GR (1) GR81504B (enExample)
IE (1) IE57694B1 (enExample)
IL (1) IL72389A (enExample)
PT (1) PT78892A (enExample)
ZA (1) ZA845384B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3064888D1 (en) * 1979-04-30 1983-10-27 Hoechst Ag Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization
JPS61277633A (ja) * 1985-05-31 1986-12-08 Toray Ind Inc インタ−フエロン組成物
US5183746A (en) * 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
US4956274A (en) * 1987-04-06 1990-09-11 Microgenics Corporation Reagent stabilization in enzyme-donor and acceptor assay
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
US5763394A (en) * 1988-04-15 1998-06-09 Genentech, Inc. Human growth hormone aqueous formulation
US5981485A (en) * 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5830452A (en) * 1990-11-20 1998-11-03 Chiron Corporation Method for enhancing the anti-tumor therapeutic index of interleukin-2
WO1993019773A1 (en) * 1992-04-07 1993-10-14 Pitman-Moore, Inc. Lyophilized somatotropin formulations
ES2153385T5 (es) † 1992-07-31 2008-09-01 Genentech, Inc. Composicion acuosa a base de hormona del crecimiento humana.
JPH11514334A (ja) * 1995-06-07 1999-12-07 チロン コーポレーション タンパク質の可溶化、精製、および再生の方法
US6790439B1 (en) 1995-06-07 2004-09-14 Zymogenetics, Inc. Thrombopoietin compositions
MX9602398A (es) * 1995-06-23 1997-02-28 Kimberly Clark Co Material polimerico modificado teniendo humectabilidad mejorada.
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
MXPA02000404A (es) * 1999-07-12 2004-05-21 Grandis Biotech Gmbh Formulaciones de hormona de crecimiento.
EP1536835A1 (en) * 2002-07-09 2005-06-08 Sandoz AG Liquid formulations with high concentration of human growth hormone (hgh) comprising phenol
JP4522997B2 (ja) * 2003-08-13 2010-08-11 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Ｔｆｐｉおよびｔｆｐｉアナログを精製するための改良された方法
UA89781C2 (uk) 2004-04-07 2010-03-10 Арес Трейдінг С.А. Рідкий склад гормона росту
EP1847830A1 (en) * 2006-04-20 2007-10-24 TF Instruments, Inc. Determining optimal concentrations of protective additives for biomolecules
WO2024133849A1 (en) * 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439355A (en) * 1976-12-02 1984-03-27 Colgate-Palmolive Company Elastic detergent product of improved foaming power after use
DE2917535C2 (de) * 1979-04-30 1986-10-30 Hoechst Ag, 6230 Frankfurt Gegen Denaturierung beständige Insulinlösungen
DE3064888D1 (en) * 1979-04-30 1983-10-27 Hoechst Ag Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization
JPS58501125A (ja) * 1981-07-17 1983-07-14 ノルデイスク・インスリンラボラトリウム 安定な水性治療性インシユリン製剤及びその製造方法

Also Published As

Publication number Publication date
ES535482A0 (es) 1986-09-01
ES534195A0 (es) 1985-10-01
DK168030B1 (da) 1994-01-24
JPH0582397B2 (enExample) 1993-11-18
IL72389A0 (en) 1984-11-30
KR850000971A (ko) 1985-03-14
EP0131864A3 (en) 1987-08-26
US4637834A (en) 1987-01-20
FI80276C (fi) 1990-05-10
AU3053784A (en) 1985-01-17
IL72389A (en) 1988-11-30
FI842798A7 (fi) 1985-01-14
IE841796L (en) 1985-01-13
JPS6038398A (ja) 1985-02-27
DK342684A (da) 1985-01-14
DE3483287D1 (de) 1990-10-31
GR81504B (enExample) 1984-12-11
FI842798A0 (fi) 1984-07-11
DK342684D0 (da) 1984-07-12
ES8600319A1 (es) 1985-10-01
FI80276B (fi) 1990-01-31
IE57694B1 (en) 1993-03-10
ATE56876T1 (de) 1990-10-15
ES8609361A1 (es) 1986-09-01
KR920002934B1 (ko) 1992-04-10
DE3325223A1 (de) 1985-01-24
EP0131864B1 (de) 1990-09-26
EP0131864A2 (de) 1985-01-23
ZA845384B (en) 1985-02-27
AU579106B2 (en) 1988-11-17

Similar Documents

Publication Publication Date Title
PT78892A (de) Gegen denaturierung bestaendige waessrige proteinloesungen verfahren zu ihrer herstellung und ihre verwendung
DE59410008D1 (de) Verfahren zur Herstellung von Perylen-3,4-dicarbonsäurederivaten
DE59105897D1 (de) Substituierte Azole, Verfahren zu deren Herstellung, diese enthaltende Mittel und deren Verwendung.
DE59310171D1 (de) Komplexe enthaltend Glykosyl-Phosphatidylinositol-Proteine und Cholansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DK0626375T3 (da) Octacyclodepsipeptider med endoparasiticid virkning
ATE46157T1 (de) Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel.
ATE66609T1 (de) Loesungen von oxazaphosphorinen mit verbesserter stabilitaet und verfahren zu deren herstellung.
ATE27289T1 (de) Copolymerisat, verfahren zu seiner herstellung und seine verwendung als sorptionsmittel.
DE58905462D1 (de) Enzym-hemmende Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und ihre Verwendung.
ATE78100T1 (de) Bifunktionelle haptene, verfahren zu ihrer herstellung und ihre verwendung.
ATE45746T1 (de) Substituierte o-acyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung.
ATE70837T1 (de) Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung.
ES2170946T3 (es) Procedimiento de preparacion de compuestos fluorados a partir de las aminas correspondientes.
AU1779188A (en) Guanidine-related compounds comprising a substituted tetraphenylborate ion, process for obtaining these compounds, and use of the compounds
PT90814A (pt) Processo de preparacao de derivados da fenotiazina
ATE44961T1 (de) Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.
ATE111894T1 (de) Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate.
ATE124219T1 (de) Von l-glutaminsäure abgeleitete süssungsmittel, verfahren zu ihrer herstellung.
DE69306908D1 (de) Verfahren zur Herstellung von Diltiazem
ATE111087T1 (de) Verfahren zur herstellung von 2-aryl-2h-1,2,3- triazolen.
DE59007185D1 (de) Substituierte 1.2.3.4-Oxatriazolium-5-olate, Verfahren zu ihrer Herstellung und ihre Verwendung.
DE3669508D1 (de) Verbrueckungsreagenz, verfahren zu seiner herstellung und seine anwendung.

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940331

NF3A Restitutio in integrum

Effective date: 19940825

PC3A Transfer or assignment

Free format text: 20010322 AVENTIS PHARMA DEUTSCHLAND GMBH DE