PT78769A - Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents - Google Patents

Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents

Info

Publication number
PT78769A
PT78769A PT78769A PT7876984A PT78769A PT 78769 A PT78769 A PT 78769A PT 78769 A PT78769 A PT 78769A PT 7876984 A PT7876984 A PT 7876984A PT 78769 A PT78769 A PT 78769A
Authority
PT
Portugal
Prior art keywords
propoxymethyl
guanine
dihydroxy
derivatives
preparing
Prior art date
Application number
PT78769A
Other languages
English (en)
Portuguese (pt)
Inventor
Wallace T Ashton
Laura F Canning
Arthur K Field
Richard L Tolman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT78769A publication Critical patent/PT78769A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78769A 1983-06-24 1984-06-20 Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents PT78769A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50732883A 1983-06-24 1983-06-24
US61691084A 1984-06-06 1984-06-06

Publications (1)

Publication Number Publication Date
PT78769A true PT78769A (en) 1984-07-01

Family

ID=27055802

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78769A PT78769A (en) 1983-06-24 1984-06-20 Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents

Country Status (10)

Country Link
EP (1) EP0130126B1 (enEXAMPLES)
AU (1) AU564194B2 (enEXAMPLES)
CA (1) CA1225400A (enEXAMPLES)
DE (1) DE3465596D1 (enEXAMPLES)
DK (1) DK306184A (enEXAMPLES)
ES (1) ES8600763A1 (enEXAMPLES)
GR (1) GR82379B (enEXAMPLES)
IL (1) IL72173A0 (enEXAMPLES)
NZ (1) NZ208634A (enEXAMPLES)
PT (1) PT78769A (enEXAMPLES)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
US5216142A (en) * 1989-04-17 1993-06-01 Efamol Holdings Plc Anti-virals
AU2641192A (en) * 1991-09-24 1993-04-27 Wellcome Foundation Limited, The Therapeutic nucleosides
US6057305A (en) * 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
US5627185A (en) * 1994-11-23 1997-05-06 Gosselin; Gilles Acyclovir derivatives as antiviral agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
CA1225400A (en) 1987-08-11
EP0130126B1 (en) 1987-08-26
IL72173A0 (en) 1984-10-31
DE3465596D1 (en) 1987-10-01
GR82379B (enEXAMPLES) 1984-12-13
AU2976384A (en) 1985-01-03
ES533618A0 (es) 1985-10-16
DK306184A (da) 1984-12-25
DK306184D0 (da) 1984-06-22
EP0130126A1 (en) 1985-01-02
NZ208634A (en) 1988-02-29
ES8600763A1 (es) 1985-10-16
AU564194B2 (en) 1987-08-06

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