PT78769A - Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents - Google Patents

Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents

Info

Publication number
PT78769A
PT78769A PT78769A PT7876984A PT78769A PT 78769 A PT78769 A PT 78769A PT 78769 A PT78769 A PT 78769A PT 7876984 A PT7876984 A PT 7876984A PT 78769 A PT78769 A PT 78769A
Authority
PT
Portugal
Prior art keywords
propoxymethyl
guanine
dihydroxy
derivatives
preparing
Prior art date
Application number
PT78769A
Other languages
English (en)
Portuguese (pt)
Inventor
Wallace T Ashton
Laura F Canning
Arthur K Field
Richard L Tolman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT78769A publication Critical patent/PT78769A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78769A 1983-06-24 1984-06-20 Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents PT78769A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50732883A 1983-06-24 1983-06-24
US61691084A 1984-06-06 1984-06-06

Publications (1)

Publication Number Publication Date
PT78769A true PT78769A (en) 1984-07-01

Family

ID=27055802

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78769A PT78769A (en) 1983-06-24 1984-06-20 Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents

Country Status (10)

Country Link
EP (1) EP0130126B1 (en:Method)
AU (1) AU564194B2 (en:Method)
CA (1) CA1225400A (en:Method)
DE (1) DE3465596D1 (en:Method)
DK (1) DK306184A (en:Method)
ES (1) ES8600763A1 (en:Method)
GR (1) GR82379B (en:Method)
IL (1) IL72173A0 (en:Method)
NZ (1) NZ208634A (en:Method)
PT (1) PT78769A (en:Method)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
US5216142A (en) * 1989-04-17 1993-06-01 Efamol Holdings Plc Anti-virals
AU2641192A (en) * 1991-09-24 1993-04-27 Wellcome Foundation Limited, The Therapeutic nucleosides
US6057305A (en) 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
US5627185A (en) * 1994-11-23 1997-05-06 Gosselin; Gilles Acyclovir derivatives as antiviral agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
ES533618A0 (es) 1985-10-16
DK306184A (da) 1984-12-25
AU564194B2 (en) 1987-08-06
ES8600763A1 (es) 1985-10-16
AU2976384A (en) 1985-01-03
EP0130126A1 (en) 1985-01-02
DK306184D0 (da) 1984-06-22
GR82379B (en:Method) 1984-12-13
IL72173A0 (en) 1984-10-31
CA1225400A (en) 1987-08-11
EP0130126B1 (en) 1987-08-26
NZ208634A (en) 1988-02-29
DE3465596D1 (en) 1987-10-01

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