PT785187E - Preparacao de sais de acido 6, 8-bis(amidiniotio)- octanoico - Google Patents

Preparacao de sais de acido 6, 8-bis(amidiniotio)- octanoico Download PDF

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Publication number
PT785187E
PT785187E PT97100224T PT97100224T PT785187E PT 785187 E PT785187 E PT 785187E PT 97100224 T PT97100224 T PT 97100224T PT 97100224 T PT97100224 T PT 97100224T PT 785187 E PT785187 E PT 785187E
Authority
PT
Portugal
Prior art keywords
acid
bis
octanoic acid
multiplet
strong
Prior art date
Application number
PT97100224T
Other languages
English (en)
Portuguese (pt)
Inventor
Klaus Huthmacher
Alfred Olbrich
Herbert Klenk
Horst Bethge
Roland Moller
Beisswenger Dr Thomas
Hubner Dr Frank
Gerhard Sator
Rainer Gewald
Stephan Rautenberg
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of PT785187E publication Critical patent/PT785187E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT97100224T 1996-01-19 1997-01-09 Preparacao de sais de acido 6, 8-bis(amidiniotio)- octanoico PT785187E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601787A DE19601787C1 (de) 1996-01-19 1996-01-19 Herstellung und Verwendung von Salzen der 6,8-Bis(amidiniumthio)-octansäure

Publications (1)

Publication Number Publication Date
PT785187E true PT785187E (pt) 2001-12-28

Family

ID=7783145

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97100224T PT785187E (pt) 1996-01-19 1997-01-09 Preparacao de sais de acido 6, 8-bis(amidiniotio)- octanoico

Country Status (9)

Country Link
US (2) US5760268A (de)
EP (1) EP0785187B1 (de)
AT (1) ATE202340T1 (de)
CA (1) CA2195354C (de)
DE (2) DE19601787C1 (de)
DK (1) DK0785187T3 (de)
ES (1) ES2160267T3 (de)
GR (1) GR3036585T3 (de)
PT (1) PT785187E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01004152A (es) 1998-10-26 2002-06-04 Univ New York State Res Found Derivados de acido lipoico y su uso en el tratamiento de enfermedades.
DE10201464B4 (de) 2002-01-16 2005-06-16 Viatris Gmbh & Co. Kg Verfahren zur Herstellung reiner Thioctsäure

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2792414A (en) * 1954-07-22 1957-05-14 Merck & Co Inc Production of alpha-lipoic acid intermediates
US2772300A (en) * 1954-07-22 1956-11-27 Merck & Co Inc Dithi-dioctanoic acids and methods of obtaining the same
FR1273856A (fr) * 1955-10-01 1961-10-20 Fr De Chimie Ind Et Biolog Soc Procédé de préparation de produits intermédiaires dans la synthèse de l'acide alpha-lipoïque et ses applications
US3223712A (en) * 1960-07-18 1965-12-14 Yamanouchi Pharma Co Ltd Synthesis of thioctic acid and thioctic acid amide
CH415604A (de) * 1961-02-02 1966-06-30 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von Acylthiohalogencaprylsäurederivaten
DE4035442B4 (de) * 1989-11-09 2010-04-29 Evonik Degussa Gmbh Arzneimittel enthaltend als Wirkstoff R-α-Liponsäure
DE4037440A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE19533881A1 (de) * 1995-09-13 1997-03-20 Dresden Arzneimittel Herstellung und Verwendung der reinen Enantiomere der 8-Chlor-6-sulfonyloxy-octansäuren und ihrer Alkylester und der reinen Enantiomere der 6,8-Dichlor-octansäure und ihrer Alkylester

Also Published As

Publication number Publication date
GR3036585T3 (en) 2001-12-31
CA2195354C (en) 2006-10-10
US5760268A (en) 1998-06-02
EP0785187A2 (de) 1997-07-23
DK0785187T3 (da) 2001-09-17
EP0785187B1 (de) 2001-06-20
CA2195354A1 (en) 1997-07-20
ATE202340T1 (de) 2001-07-15
DE59703836D1 (de) 2001-07-26
ES2160267T3 (es) 2001-11-01
DE19601787C1 (de) 1997-07-24
EP0785187A3 (de) 1997-11-19
US6013815A (en) 2000-01-11

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