PT77848B - Process for the racemisation of spiro compounds - Google Patents
Process for the racemisation of spiro compoundsInfo
- Publication number
- PT77848B PT77848B PT77848A PT7784883A PT77848B PT 77848 B PT77848 B PT 77848B PT 77848 A PT77848 A PT 77848A PT 7784883 A PT7784883 A PT 7784883A PT 77848 B PT77848 B PT 77848B
- Authority
- PT
- Portugal
- Prior art keywords
- racemisation
- spiro compounds
- triones
- indoline
- substituted spiro
- Prior art date
Links
- 150000003413 spiro compounds Chemical class 0.000 title 1
- 125000003003 spiro group Chemical class 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
- Storage Of Web-Like Or Filamentary Materials (AREA)
- Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8236969 | 1982-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT77848A PT77848A (en) | 1984-01-01 |
| PT77848B true PT77848B (en) | 1986-07-11 |
Family
ID=10535286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT77848A PT77848B (en) | 1982-12-20 | 1983-12-19 | Process for the racemisation of spiro compounds |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0115679B1 (pt) |
| JP (1) | JPS59118787A (pt) |
| KR (1) | KR840007407A (pt) |
| AT (1) | ATE30233T1 (pt) |
| AU (1) | AU567312B2 (pt) |
| CA (1) | CA1209148A (pt) |
| CS (1) | CS240986B2 (pt) |
| DD (1) | DD216935A5 (pt) |
| DE (1) | DE3374060D1 (pt) |
| DK (1) | DK579283A (pt) |
| ES (1) | ES528173A0 (pt) |
| FI (1) | FI834637A7 (pt) |
| GB (1) | GB8331194D0 (pt) |
| GR (1) | GR79707B (pt) |
| HU (1) | HU189824B (pt) |
| IE (1) | IE56288B1 (pt) |
| NO (1) | NO834687L (pt) |
| NZ (1) | NZ206619A (pt) |
| PL (1) | PL245203A1 (pt) |
| PT (1) | PT77848B (pt) |
| ZA (1) | ZA838930B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8415635D0 (en) * | 1984-06-19 | 1984-07-25 | Ici Plc | Cyclic amides |
| TW200801011A (en) | 2006-02-07 | 2008-01-01 | Astrazeneca Ab | New compounds II |
| US20090076049A1 (en) * | 2006-02-07 | 2009-03-19 | Astrazeneca Ab | Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3024231A (en) * | 1959-02-11 | 1962-03-06 | Spencer Chem Co | Racemization of d- and l-isomers of alpha-amino-epsilon-carprolactam |
| GB1569486A (en) * | 1976-12-22 | 1980-06-18 | Merck & Co Inc | Racemisationof 6-oxo-2-piperidine-carboxylic acid entantiomers |
| IE50332B1 (en) * | 1979-11-13 | 1986-04-02 | Ici Ltd | 1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof |
| IE53102B1 (en) * | 1981-05-12 | 1988-06-22 | Ici Plc | Pharmaceutical spiro-succinimide derivatives |
| GB8312379D0 (en) * | 1983-05-05 | 1983-06-08 | Ici Plc | Heterocyclic compounds |
-
1983
- 1983-11-23 GB GB838331194A patent/GB8331194D0/en active Pending
- 1983-11-29 IE IE2808/83A patent/IE56288B1/en not_active IP Right Cessation
- 1983-11-30 AU AU21852/83A patent/AU567312B2/en not_active Ceased
- 1983-11-30 ZA ZA838930A patent/ZA838930B/xx unknown
- 1983-12-07 AT AT83307446T patent/ATE30233T1/de not_active IP Right Cessation
- 1983-12-07 GR GR73172A patent/GR79707B/el unknown
- 1983-12-07 DE DE8383307446T patent/DE3374060D1/de not_active Expired
- 1983-12-07 EP EP83307446A patent/EP0115679B1/en not_active Expired
- 1983-12-15 DK DK579283A patent/DK579283A/da not_active Application Discontinuation
- 1983-12-16 FI FI834637A patent/FI834637A7/fi not_active Application Discontinuation
- 1983-12-16 DD DD83258088A patent/DD216935A5/de unknown
- 1983-12-19 PL PL24520383A patent/PL245203A1/xx unknown
- 1983-12-19 NO NO834687A patent/NO834687L/no unknown
- 1983-12-19 NZ NZ206619A patent/NZ206619A/en unknown
- 1983-12-19 HU HU834320A patent/HU189824B/hu unknown
- 1983-12-19 KR KR1019830005998A patent/KR840007407A/ko not_active Withdrawn
- 1983-12-19 ES ES528173A patent/ES528173A0/es active Granted
- 1983-12-19 CA CA000443630A patent/CA1209148A/en not_active Expired
- 1983-12-19 CS CS839612A patent/CS240986B2/cs unknown
- 1983-12-19 PT PT77848A patent/PT77848B/pt not_active IP Right Cessation
- 1983-12-20 JP JP58239004A patent/JPS59118787A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CS961283A2 (en) | 1985-06-13 |
| ZA838930B (en) | 1985-04-24 |
| ATE30233T1 (de) | 1987-10-15 |
| AU2185283A (en) | 1984-06-28 |
| CS240986B2 (en) | 1986-03-13 |
| GR79707B (pt) | 1984-10-31 |
| NZ206619A (en) | 1986-09-10 |
| IE56288B1 (en) | 1991-06-05 |
| CA1209148A (en) | 1986-08-05 |
| PT77848A (en) | 1984-01-01 |
| EP0115679A1 (en) | 1984-08-15 |
| DK579283A (da) | 1984-06-21 |
| IE832808L (en) | 1984-06-20 |
| JPS59118787A (ja) | 1984-07-09 |
| DK579283D0 (da) | 1983-12-15 |
| ES8600298A1 (es) | 1985-10-01 |
| EP0115679B1 (en) | 1987-10-14 |
| PL245203A1 (en) | 1985-03-12 |
| NO834687L (no) | 1984-06-21 |
| FI834637A7 (fi) | 1984-06-21 |
| AU567312B2 (en) | 1987-11-19 |
| KR840007407A (ko) | 1984-12-07 |
| DD216935A5 (de) | 1985-01-02 |
| ES528173A0 (es) | 1985-10-01 |
| GB8331194D0 (en) | 1983-12-29 |
| DE3374060D1 (en) | 1987-11-19 |
| FI834637A0 (fi) | 1983-12-16 |
| HU189824B (en) | 1986-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19980131 |