PT72925B - Process for preparing immunologically active dipeptidyl 5-0, 6-0-acyl-2-amino-deoxy-d-glucofuranose derivatives - Google Patents

Process for preparing immunologically active dipeptidyl 5-0, 6-0-acyl-2-amino-deoxy-d-glucofuranose derivatives

Info

Publication number
PT72925B
PT72925B PT72925A PT7292581A PT72925B PT 72925 B PT72925 B PT 72925B PT 72925 A PT72925 A PT 72925A PT 7292581 A PT7292581 A PT 7292581A PT 72925 B PT72925 B PT 72925B
Authority
PT
Portugal
Prior art keywords
hydrogen
alkyl
immunologically active
deoxy
acyl
Prior art date
Application number
PT72925A
Other languages
English (en)
Other versions
PT72925A (en
Inventor
Phillipe L Durette
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT72925A publication Critical patent/PT72925A/pt
Publication of PT72925B publication Critical patent/PT72925B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
PT72925A 1980-05-05 1981-04-27 Process for preparing immunologically active dipeptidyl 5-0, 6-0-acyl-2-amino-deoxy-d-glucofuranose derivatives PT72925B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/146,806 US4310514A (en) 1980-05-05 1980-05-05 Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation

Publications (2)

Publication Number Publication Date
PT72925A PT72925A (en) 1981-05-01
PT72925B true PT72925B (en) 1985-11-25

Family

ID=22519075

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72925A PT72925B (en) 1980-05-05 1981-04-27 Process for preparing immunologically active dipeptidyl 5-0, 6-0-acyl-2-amino-deoxy-d-glucofuranose derivatives

Country Status (10)

Country Link
US (1) US4310514A (pt)
EP (1) EP0039637B1 (pt)
JP (1) JPS56169697A (pt)
AT (1) ATE6863T1 (pt)
CA (1) CA1175804A (pt)
DE (1) DE3162856D1 (pt)
DK (1) DK197181A (pt)
ES (1) ES8207552A1 (pt)
GR (1) GR75655B (pt)
PT (1) PT72925B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US5370871A (en) * 1983-01-24 1994-12-06 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US5126131A (en) * 1983-01-24 1992-06-30 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of antigen-competitive conjugates.
US6022544A (en) 1983-01-24 2000-02-08 The John Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
FR2564096B1 (fr) * 1984-05-11 1988-02-19 Anvar Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir
US4866036A (en) * 1987-10-05 1989-09-12 Merck & Co., Inc. Dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose compositions and methods of use in aids-immunocompromised human hosts
US5089470A (en) * 1988-08-26 1992-02-18 The United State Of America As Represented By The United States Department Of Energy Compositions containing poly (γ-glutamylcysteinyl)glycines
EP0492478B1 (en) * 1990-12-21 1995-07-19 Pliva Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrija S P.O. Tert-butyloxycarbonyl-L-tyrosyl-peptidoglycan monomer and 125 I-labelled derivative thereof, their preparation and use
US6488929B2 (en) 1994-05-23 2002-12-03 Montana State University Candida albicans phosphomannan complex as a vaccine
US6309642B1 (en) 1997-04-28 2001-10-30 The Research And Development Institute, Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine
WO1995031998A1 (en) * 1994-05-23 1995-11-30 The Research & Development Institute, Inc. Candida albicans adhesin as a vaccine
US20030072775A1 (en) * 1997-04-28 2003-04-17 The Research And Development Institute Inc. Peptides which mimic candida carbohydrate epitopes and their use in a vaccine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2248025A2 (en) 1973-10-23 1975-05-16 Anvar Vaccine compsns. - contg. N-acyl muramic acid deriv. as adjuvant
FR2288527A2 (fr) 1974-10-22 1976-05-21 Anvar Compositions contenant de la n-acetyl-muramyl- l-alanyl - d-isoglutamine ou de l'acide n-acetyl-muramyl-l-alanyl - d-glutamique, exemptes d'huile et ayant des proprietes adjuvantes
FR2326930A1 (fr) 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
CH613709A5 (en) 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
US4153684A (en) * 1976-03-10 1979-05-08 Agence Nationale De Valorisation De La Recherche (Anvar) Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
GB1563561A (en) * 1976-06-23 1980-03-26 Daiichi Seiyaku Co Muramyldipeptide derivatives and process for the preparation thereof

Also Published As

Publication number Publication date
DE3162856D1 (en) 1984-05-03
US4310514A (en) 1982-01-12
ES501865A0 (es) 1982-10-01
ATE6863T1 (de) 1984-04-15
JPS56169697A (en) 1981-12-26
EP0039637B1 (en) 1984-03-28
DK197181A (da) 1981-12-11
PT72925A (en) 1981-05-01
GR75655B (pt) 1984-08-02
EP0039637A1 (en) 1981-11-11
ES8207552A1 (es) 1982-10-01
CA1175804A (en) 1984-10-09

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