PT721470E - Anticorpos monoclonais para utilizacao em diagnostico e tratamento de cancro colorrectal - Google Patents

Anticorpos monoclonais para utilizacao em diagnostico e tratamento de cancro colorrectal

Info

Publication number
PT721470E
PT721470E PT94923816T PT94923816T PT721470E PT 721470 E PT721470 E PT 721470E PT 94923816 T PT94923816 T PT 94923816T PT 94923816 T PT94923816 T PT 94923816T PT 721470 E PT721470 E PT 721470E
Authority
PT
Portugal
Prior art keywords
pct
chain
sequence
human
residues
Prior art date
Application number
PT94923816T
Other languages
English (en)
Inventor
Lorna Mary Dyet Stewart
Walter Fred Bodmer
Helga Durbin
David Snary
Susan Young
Paul Alan Bates
Original Assignee
Cancer Rec Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Rec Tech Ltd filed Critical Cancer Rec Tech Ltd
Publication of PT721470E publication Critical patent/PT721470E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT94923816T 1993-08-21 1994-08-19 Anticorpos monoclonais para utilizacao em diagnostico e tratamento de cancro colorrectal PT721470E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939317423A GB9317423D0 (en) 1993-08-21 1993-08-21 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
PT721470E true PT721470E (pt) 2003-03-31

Family

ID=10740834

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94923816T PT721470E (pt) 1993-08-21 1994-08-19 Anticorpos monoclonais para utilizacao em diagnostico e tratamento de cancro colorrectal

Country Status (12)

Country Link
US (1) US5965710A (pt)
EP (1) EP0721470B1 (pt)
JP (1) JP3492373B2 (pt)
AT (1) ATE226596T1 (pt)
AU (1) AU7390694A (pt)
CA (1) CA2168440C (pt)
DE (1) DE69431602T2 (pt)
DK (1) DK0721470T3 (pt)
ES (1) ES2187529T3 (pt)
GB (1) GB9317423D0 (pt)
PT (1) PT721470E (pt)
WO (1) WO1995006067A1 (pt)

Families Citing this family (30)

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US5872215A (en) * 1991-12-02 1999-02-16 Medical Research Council Specific binding members, materials and methods
GB9621295D0 (en) * 1995-12-07 1996-11-27 Cambridge Antibody Tech Specific binding members,materials and methods
US6417337B1 (en) * 1996-10-31 2002-07-09 The Dow Chemical Company High affinity humanized anti-CEA monoclonal antibodies
WO1999006834A2 (en) * 1997-08-04 1999-02-11 Ixsys, Incorporated Methods for identifying ligand specific binding molecules
DE19739685A1 (de) * 1997-09-10 1999-03-11 Eichel Streiber Christoph Von Monoklonale Antikörper zur Therapie und Prophylaxe von Erkrankungen durch Clostridium difficile
EP1212075A4 (en) * 1999-08-26 2005-11-23 Keith M Skubitz PEPTIDES CAPABLE OF MODULATING THE FUNCTION OF MEMBERS OF THE CD66 FAMILY (CEACAM)
US6835549B2 (en) * 2000-02-24 2004-12-28 University Of Medicine & Dentistry Of New Jersey Immunoassay method for the diagnosis of gastric intestinal metaplasia associated with gastric carcinoma
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
EP1472276A4 (en) * 2001-02-28 2007-05-09 Keith M Skubitz PEPTIDES OF SMALL SIZE CAPACITY TO MODULATE THE FUNCTION OF THE MEMBERS OF THE FAMILY OF CD66 (CEACAM)
US20060068433A1 (en) * 2004-09-20 2006-03-30 Godfrey Tony E Multiple mode multiplex reaction quenching method
CA2439402A1 (en) * 2001-03-02 2002-09-12 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pcr method
EP2000482A1 (en) * 2001-06-20 2008-12-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP1599728A1 (en) * 2003-03-04 2005-11-30 Auburn University Methods of forming monolayers of phage-derived products and uses thereof
WO2005114444A1 (en) * 2004-04-30 2005-12-01 America Online, Inc. Network configuration management
US8187595B2 (en) 2004-05-07 2012-05-29 The University Of North Carolina At Chapel Hill Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor-I
NZ595387A (en) 2005-08-11 2013-04-26 Arpi Matossian Rogers Peptides for treatment and diagnosis of autoimmune disease
EP1940355B1 (en) 2005-09-30 2012-12-19 Auburn University Targeted drug delivery nanocarrier comprising a targeting landscape phage protein assembly
US8119352B2 (en) * 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
JP5552437B2 (ja) * 2008-02-29 2014-07-16 シグナロミクス ゲーエムベーハー 最適化されたアドへシンフラグメントおよび対応するナノ粒子
CA2770174A1 (en) * 2009-08-31 2011-03-03 Roche Glycart Ag Affinity-matured humanized anti cea monoclonal antibodies
AU2010303142B2 (en) * 2009-09-29 2013-05-09 Roche Glycart Ag Bispecific death receptor agonistic antibodies
WO2011109769A1 (en) 2010-03-04 2011-09-09 Ventana Medical Systems, Inc. Processing system for processing specimens using acoustic energy
US10539487B2 (en) 2010-03-04 2020-01-21 Ventana Medical Systems, Inc. Systems and methods for monitoring tissue sample processing
US10126216B2 (en) 2011-02-17 2018-11-13 Ventana Medical Systems, Inc. Method for tissue sample fixation
LT2681244T (lt) 2011-03-02 2018-02-12 Roche Glycart Ag Cea antikūnai
EA201892619A1 (ru) 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
US9073996B2 (en) 2012-08-31 2015-07-07 The University Of North Carolina At Chapel Hill Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor 1 (IGF-1)
UA118028C2 (uk) 2013-04-03 2018-11-12 Рош Глікарт Аг Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
US9753036B2 (en) 2014-04-29 2017-09-05 Edp Biotech Corporation Methods and compositions for screening and detecting biomarkers
AU2023237620A1 (en) 2022-03-23 2024-08-29 Synaffix B.V. Antibody-conjugates for targeting of tumours expressing carcinoembyronic antigen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU625613B2 (en) * 1988-01-05 1992-07-16 Novartis Ag Novel chimeric antibodies

Also Published As

Publication number Publication date
DK0721470T3 (da) 2003-02-24
ES2187529T3 (es) 2003-06-16
CA2168440A1 (en) 1995-03-02
JP3492373B2 (ja) 2004-02-03
DE69431602T2 (de) 2003-06-26
ATE226596T1 (de) 2002-11-15
US5965710A (en) 1999-10-12
DE69431602D1 (de) 2002-11-28
EP0721470A1 (en) 1996-07-17
WO1995006067A1 (en) 1995-03-02
JPH09501571A (ja) 1997-02-18
EP0721470B1 (en) 2002-10-23
GB9317423D0 (en) 1993-10-06
AU7390694A (en) 1995-03-21
CA2168440C (en) 2002-07-23

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