PT3830254T - Novas esterases e suas utilizações - Google Patents
Novas esterases e suas utilizaçõesInfo
- Publication number
- PT3830254T PT3830254T PT197426190T PT19742619T PT3830254T PT 3830254 T PT3830254 T PT 3830254T PT 197426190 T PT197426190 T PT 197426190T PT 19742619 T PT19742619 T PT 19742619T PT 3830254 T PT3830254 T PT 3830254T
- Authority
- PT
- Portugal
- Prior art keywords
- novel esterases
- esterases
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J11/00—Recovery or working-up of waste materials
- C08J11/04—Recovery or working-up of waste materials of polymers
- C08J11/10—Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J11/00—Recovery or working-up of waste materials
- C08J11/04—Recovery or working-up of waste materials of polymers
- C08J11/10—Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation
- C08J11/105—Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with enzymes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01074—Cutinase (3.1.1.74)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/62—Plastics recycling; Rubber recycling
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Sustainable Development (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18306018 | 2018-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3830254T true PT3830254T (pt) | 2025-01-24 |
Family
ID=63144937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT197426190T PT3830254T (pt) | 2018-07-27 | 2019-07-26 | Novas esterases e suas utilizações |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11535832B2 (https=) |
| EP (2) | EP4424823B1 (https=) |
| JP (2) | JP7519987B2 (https=) |
| KR (2) | KR20260004534A (https=) |
| CN (2) | CN120173910A (https=) |
| CA (1) | CA3107517A1 (https=) |
| ES (1) | ES3006610T3 (https=) |
| LT (1) | LT3830254T (https=) |
| MX (1) | MX2021001046A (https=) |
| PT (1) | PT3830254T (https=) |
| WO (1) | WO2020021116A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107709457B (zh) | 2015-06-12 | 2021-05-25 | 卡比奥斯公司 | 可生物降解聚酯组合物及其用途 |
| MX2018014090A (es) | 2016-05-19 | 2019-04-01 | Carbios | Un proceso para degradar productos de plastico. |
| WO2018011284A1 (en) | 2016-07-12 | 2018-01-18 | Carbios | Novel esterases and uses thereof |
| BR112019012258A2 (pt) | 2016-12-16 | 2020-10-20 | Carbios | proteases de degradação de plástico aprimoradas |
| JP7217267B2 (ja) | 2017-08-31 | 2023-02-02 | キャルビオス | 生物学的実体を含む液体組成物及びその使用 |
| KR20200103757A (ko) | 2017-12-21 | 2020-09-02 | 까르비오 | 신규한 프로테아제 및 이의 용도 |
| JP7601756B2 (ja) | 2018-07-27 | 2024-12-17 | キャルビオス | 新規なエステラーゼ及びその使用 |
| PT3830254T (pt) | 2018-07-27 | 2025-01-24 | Carbios | Novas esterases e suas utilizações |
| US11692181B2 (en) | 2018-07-27 | 2023-07-04 | Carbios | Esterases and uses thereof |
| FR3088070B1 (fr) | 2018-11-06 | 2021-11-26 | Carbios | Procede de degradation enzymatique de polyethylene terephtalate |
| CA3129549A1 (en) | 2019-03-28 | 2020-10-01 | Carbios | Multicomponent thermoplastic product |
| CA3145635A1 (en) | 2019-07-11 | 2021-01-14 | Carbios | Esterases and uses thereof |
| JP7638952B2 (ja) * | 2019-07-11 | 2025-03-04 | キャルビオス | 新規エステラーゼ及びその使用 |
| GB202005073D0 (en) | 2020-04-06 | 2020-05-20 | Mellizyme Biotechnology Ltd | Enzymatic degradation of plastics |
| WO2022090288A1 (en) * | 2020-10-27 | 2022-05-05 | Carbios | Novel esterases and uses thereof |
| CN116615491A (zh) | 2020-10-27 | 2023-08-18 | 卡比奥斯公司 | 新酯酶及其用途 |
| CN114438140B (zh) * | 2020-11-02 | 2024-05-17 | 华南理工大学 | Pet的降解方法 |
| AU2022277645A1 (en) | 2021-05-20 | 2023-11-30 | Carbios | Process for degrading a plastic product comprising at least one polyester |
| CN117413007A (zh) | 2021-05-20 | 2024-01-16 | 卡比奥斯公司 | 降解包含至少一种聚酯的塑料产品的方法 |
| CN117597424A (zh) * | 2021-06-30 | 2024-02-23 | 汉高股份有限及两合公司 | 具有改进的水分管理性能的组合物 |
| CN113698742B (zh) * | 2021-08-31 | 2022-11-22 | 江南大学 | 一种聚对苯二甲酸乙二醇酯的改性方法及其在酶解过程中的应用 |
| WO2023088909A2 (en) * | 2021-11-16 | 2023-05-25 | Carbios | Novel esterases and uses thereof |
| US20250019678A1 (en) * | 2021-11-16 | 2025-01-16 | Carbios | Esterases and uses thereof |
| CN114891767B (zh) * | 2022-05-19 | 2023-04-28 | 华南理工大学 | 角质酶-酯酶融合蛋白及其应用 |
| WO2023242197A1 (en) | 2022-06-13 | 2023-12-21 | Carbios | Process for purifying mono-ethylene glycol |
| EP4321616A1 (en) | 2022-08-09 | 2024-02-14 | Covestro Deutschland AG | Thermally stable carboxylic ester hydrolases in layered double hydroxides for intrinsic recyclable polymers |
| US20240228727A1 (en) | 2023-01-09 | 2024-07-11 | Protein Evolution Inc. | Systems and methods for pretreatment and/or enzymatic degradation of crystallizable polymers, including copolymers |
| US20240352064A1 (en) | 2023-03-21 | 2024-10-24 | Protein Evolution Inc. | Methods and compositions for the separation of particles from a fluid |
| TW202511480A (zh) | 2023-05-15 | 2025-03-16 | 法商卡爾畢歐斯公司 | 新穎之酯酶及其用途 |
| CN121175416A (zh) | 2023-05-15 | 2025-12-19 | 卡比奥斯公司 | 酯酶变体及其在聚酯降解中的用途 |
| IT202300014223A1 (it) * | 2023-07-07 | 2025-01-07 | Milano Politecnico | Enzima ingegnerizzato termostabile |
| CN120905186B (zh) * | 2025-09-28 | 2026-03-17 | 源天生物科技(天津)有限公司 | BhrPETase突变体及其应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012099018A1 (ja) * | 2011-01-19 | 2012-07-26 | 天野エンザイム株式会社 | 枝葉コンポスト由来新規エステラーゼ |
| EP2751263A1 (en) * | 2011-08-31 | 2014-07-09 | Danisco US Inc. | Compositions and methods comprising a lipolytic enzyme variant |
| FR2984354A1 (fr) | 2011-12-20 | 2013-06-21 | Centre Nat Rech Scient | Procede de preparation d'alliage polymere/enzymes |
| BR112014014410A2 (pt) * | 2011-12-22 | 2019-09-24 | Danisco Us Inc | composições e métodos que compreendem uma variante de enzima lipolítica |
| EP2922906B1 (en) | 2012-11-20 | 2018-10-31 | Carbios | Method for recycling plastic products |
| EP3065890A2 (en) | 2013-11-05 | 2016-09-14 | Carbios | A method for degrading a plastic |
| DE102014204374A1 (de) * | 2014-03-11 | 2015-09-17 | Henkel Ag & Co. Kgaa | PET-Esterasen und deren Verwendung |
| CA2947478C (en) | 2014-05-16 | 2022-09-13 | Carbios | Process of recycling mixed pet plastic articles |
| TN2017000085A1 (en) | 2014-10-21 | 2018-07-04 | Carbios | Polypeptide having a polyester degrading activity and uses thereof |
| US10626242B2 (en) | 2014-12-19 | 2020-04-21 | Carbios | Plastic compound and preparation process |
| EP3268469A1 (en) | 2015-03-13 | 2018-01-17 | Carbios | New polypeptide having a polyester degrading activity and uses thereof |
| CN107709457B (zh) | 2015-06-12 | 2021-05-25 | 卡比奥斯公司 | 可生物降解聚酯组合物及其用途 |
| US10717996B2 (en) | 2015-12-21 | 2020-07-21 | Carbios | Recombinant yeast cells producing polylactic acid and uses thereof |
| MX2018014090A (es) | 2016-05-19 | 2019-04-01 | Carbios | Un proceso para degradar productos de plastico. |
| WO2018011284A1 (en) * | 2016-07-12 | 2018-01-18 | Carbios | Novel esterases and uses thereof |
| CA3030469C (en) * | 2016-07-12 | 2024-04-30 | Carbios | Esterases and uses thereof |
| BR112019012258A2 (pt) | 2016-12-16 | 2020-10-20 | Carbios | proteases de degradação de plástico aprimoradas |
| DE102017214870A1 (de) * | 2017-08-24 | 2019-03-14 | Henkel Ag & Co. Kgaa | Verbesserte Pflegeeigenschaften von Polyester Textilien II |
| WO2019043134A1 (en) | 2017-08-31 | 2019-03-07 | Carbiolice | BIODEGRADABLE POLYESTER ARTICLE COMPRISING ENZYMES |
| JP7217267B2 (ja) | 2017-08-31 | 2023-02-02 | キャルビオス | 生物学的実体を含む液体組成物及びその使用 |
| KR20200103757A (ko) | 2017-12-21 | 2020-09-02 | 까르비오 | 신규한 프로테아제 및 이의 용도 |
| DE102018210609A1 (de) | 2018-06-28 | 2020-01-02 | Henkel Ag & Co. Kgaa | Polyesterase II |
| PT3830254T (pt) | 2018-07-27 | 2025-01-24 | Carbios | Novas esterases e suas utilizações |
| JP7601756B2 (ja) | 2018-07-27 | 2024-12-17 | キャルビオス | 新規なエステラーゼ及びその使用 |
| US11692181B2 (en) | 2018-07-27 | 2023-07-04 | Carbios | Esterases and uses thereof |
| FR3088070B1 (fr) | 2018-11-06 | 2021-11-26 | Carbios | Procede de degradation enzymatique de polyethylene terephtalate |
| FR3088069B1 (fr) | 2018-11-06 | 2021-11-26 | Carbios | Procede de production d'acide terephtalique a l'echelle industrielle |
| CA3129549A1 (en) | 2019-03-28 | 2020-10-01 | Carbios | Multicomponent thermoplastic product |
| JP7638952B2 (ja) | 2019-07-11 | 2025-03-04 | キャルビオス | 新規エステラーゼ及びその使用 |
| CA3145635A1 (en) | 2019-07-11 | 2021-01-14 | Carbios | Esterases and uses thereof |
| EP4061934A1 (en) | 2019-11-18 | 2022-09-28 | Carbios | Novel proteases and uses thereof |
| WO2021123299A1 (en) | 2019-12-19 | 2021-06-24 | Carbios | Process for degrading plastic products |
| EP3838976B1 (en) | 2019-12-19 | 2025-02-12 | Carbios | Process for degrading plastic products |
| WO2021123328A1 (en) | 2019-12-19 | 2021-06-24 | Carbios | Foamed plastic compositions |
-
2019
- 2019-07-26 PT PT197426190T patent/PT3830254T/pt unknown
- 2019-07-26 CN CN202510331685.6A patent/CN120173910A/zh active Pending
- 2019-07-26 KR KR1020257040976A patent/KR20260004534A/ko active Pending
- 2019-07-26 WO PCT/EP2019/070287 patent/WO2020021116A1/en not_active Ceased
- 2019-07-26 LT LTEPPCT/EP2019/070287T patent/LT3830254T/lt unknown
- 2019-07-26 ES ES19742619T patent/ES3006610T3/es active Active
- 2019-07-26 CN CN201980057846.XA patent/CN112654701B/zh active Active
- 2019-07-26 EP EP24185157.5A patent/EP4424823B1/en active Active
- 2019-07-26 EP EP19742619.0A patent/EP3830254B1/en active Active
- 2019-07-26 KR KR1020217006317A patent/KR102899059B1/ko active Active
- 2019-07-26 MX MX2021001046A patent/MX2021001046A/es unknown
- 2019-07-26 US US17/263,569 patent/US11535832B2/en active Active
- 2019-07-26 CA CA3107517A patent/CA3107517A1/en active Pending
- 2019-07-26 JP JP2021504394A patent/JP7519987B2/ja active Active
-
2022
- 2022-12-22 US US18/145,073 patent/US11926851B2/en active Active
-
2024
- 2024-03-19 JP JP2024043973A patent/JP2024073628A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11926851B2 (en) | 2024-03-12 |
| EP4424823C0 (en) | 2025-12-03 |
| KR20260004534A (ko) | 2026-01-08 |
| US20210163906A1 (en) | 2021-06-03 |
| EP4424823B1 (en) | 2025-12-03 |
| CA3107517A1 (en) | 2020-01-30 |
| CN120173910A (zh) | 2025-06-20 |
| JP2021531030A (ja) | 2021-11-18 |
| CN112654701A (zh) | 2021-04-13 |
| US20230212537A1 (en) | 2023-07-06 |
| EP3830254A1 (en) | 2021-06-09 |
| US11535832B2 (en) | 2022-12-27 |
| LT3830254T (lt) | 2025-03-10 |
| KR102899059B1 (ko) | 2025-12-11 |
| WO2020021116A1 (en) | 2020-01-30 |
| CN112654701B (zh) | 2025-04-08 |
| KR20210042336A (ko) | 2021-04-19 |
| EP4424823A2 (en) | 2024-09-04 |
| EP4424823A3 (en) | 2024-12-25 |
| ES3006610T3 (en) | 2025-03-18 |
| MX2021001046A (es) | 2021-04-12 |
| JP7519987B2 (ja) | 2024-07-22 |
| EP3830254B1 (en) | 2024-12-11 |
| JP2024073628A (ja) | 2024-05-29 |
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