PT3573600T - Método para fabrico de uma emulsão estável para distribuição de péptidos - Google Patents

Método para fabrico de uma emulsão estável para distribuição de péptidos

Info

Publication number
PT3573600T
PT3573600T PT187107602T PT18710760T PT3573600T PT 3573600 T PT3573600 T PT 3573600T PT 187107602 T PT187107602 T PT 187107602T PT 18710760 T PT18710760 T PT 18710760T PT 3573600 T PT3573600 T PT 3573600T
Authority
PT
Portugal
Prior art keywords
manufacturing
stable emulsion
peptide delivery
peptide
delivery
Prior art date
Application number
PT187107602T
Other languages
English (en)
Original Assignee
Ose Immunotherapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ose Immunotherapeutics filed Critical Ose Immunotherapeutics
Publication of PT3573600T publication Critical patent/PT3573600T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001106Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/00118Cancer antigens from embryonic or fetal origin
    • A61K39/001182Carcinoembryonic antigen [CEA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Colloid Chemistry (AREA)
PT187107602T 2017-01-25 2018-01-24 Método para fabrico de uma emulsão estável para distribuição de péptidos PT3573600T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17305079 2017-01-25

Publications (1)

Publication Number Publication Date
PT3573600T true PT3573600T (pt) 2022-05-11

Family

ID=57965869

Family Applications (1)

Application Number Title Priority Date Filing Date
PT187107602T PT3573600T (pt) 2017-01-25 2018-01-24 Método para fabrico de uma emulsão estável para distribuição de péptidos

Country Status (23)

Country Link
US (2) US11325959B2 (pt)
EP (2) EP3573600B1 (pt)
JP (1) JP7140778B2 (pt)
KR (1) KR102577036B1 (pt)
CN (2) CN114917189B (pt)
AR (1) AR113209A1 (pt)
AU (1) AU2018213890B2 (pt)
BR (1) BR112019014917A2 (pt)
CA (1) CA3047492C (pt)
DK (1) DK3573600T3 (pt)
ES (1) ES2913268T3 (pt)
HR (1) HRP20220605T1 (pt)
HU (1) HUE058717T2 (pt)
IL (1) IL267237A (pt)
LT (1) LT3573600T (pt)
MX (1) MX2019008878A (pt)
PL (1) PL3573600T3 (pt)
PT (1) PT3573600T (pt)
RS (1) RS63259B1 (pt)
SI (1) SI3573600T1 (pt)
TW (1) TWI793099B (pt)
WO (1) WO2018138110A1 (pt)
ZA (1) ZA201905487B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3573600T1 (sl) 2017-01-25 2022-07-29 Ose Immunotherapeutics Postopek za proizvodnjo obstojne emulzije za dostavo peptida

Family Cites Families (35)

* Cited by examiner, † Cited by third party
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WO2004094454A2 (en) * 2003-04-18 2004-11-04 Idm Pharma, Inc. Hla-a2 tumor associated antigen peptides and compositions
EP2687540A1 (en) 2006-10-17 2014-01-22 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing MPHOSPH1 or DEPDC1 polypeptides
TWI610939B (zh) 2007-02-21 2018-01-11 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
CN101835892B (zh) 2007-08-20 2013-11-06 肿瘤疗法科学股份有限公司 Cdca1肽和包含cdca1肽的药剂
WO2009109855A2 (en) 2008-03-06 2009-09-11 University Of Medicine And Dentistry Of New Jersey Immunotherapy for unresectable pancreatic cancer
EP2362906B1 (en) 2008-10-22 2015-04-08 Oncotherapy Science, Inc. Rab6kifl/kif20a epitope peptide and vaccines containing the same
TWI507204B (zh) 2009-05-26 2015-11-11 Oncotherapy Science Inc Cdc45l胜肽與含此胜肽之疫苗
EP2292258A1 (en) * 2009-08-18 2011-03-09 Pevion Biotech Ltd. Multiepitope vaccine for Her2/neu-associated cancers
TW201124530A (en) 2009-12-01 2011-07-16 Oncotherapy Science Inc IMP-3 oligopeptides and vaccines including the same
CA2792910A1 (en) 2010-03-11 2011-09-15 Yusuke Nakamura Hjurp peptides and vaccines including the same
TW201216982A (en) 2010-10-21 2012-05-01 Oncotherapy Science Inc WDHD1 peptides and vaccines including the same
CA2815100A1 (en) 2010-10-21 2012-04-26 Oncotherapy Science, Inc. C18orf54 peptides and vaccines including the same
AU2011336019B2 (en) 2010-12-02 2016-07-07 Oncotherapy Science, Inc. TOMM34 peptides and vaccines including the same
TW201302800A (zh) 2011-06-10 2013-01-16 Oncotherapy Science Inc Sema5b胜肽及含其之疫苗
KR102015648B1 (ko) 2011-08-12 2019-08-28 온코세라피 사이언스 가부시키가이샤 Mphosph1 펩티드 및 이를 포함한 백신
SG10201608552WA (en) 2011-10-28 2016-12-29 Oncotherapy Science Inc Topk Peptides And Vaccines Including The Same
BR112014012819B1 (pt) 2011-11-28 2022-08-16 Merck Patent Gmbh Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
DK2895600T3 (da) 2012-09-11 2020-04-27 Onco Therapy Science Inc Ube2t-peptider og vacciner, der indeholder disse
CN105163754B (zh) 2012-09-20 2018-01-05 王荣福 前列腺特异性肿瘤抗原及其用途
US20150359867A1 (en) 2013-02-14 2015-12-17 Immunocellular Therapeutics, Ltd. Ovarian cancer vaccines and vaccination methods
WO2014136453A1 (en) 2013-03-08 2014-09-12 Oncotherapy Science, Inc. C12orf48 PEPTIDES AND VACCINES CONTAINING THE SAME
WO2014141652A1 (en) 2013-03-11 2014-09-18 Oncotherapy Science, Inc. Smyd3 peptides and vaccines containing the same
TWI658049B (zh) 2013-03-12 2019-05-01 腫瘤療法 科學股份有限公司 Kntc2胜肽及含此胜肽之疫苗
WO2014162962A1 (ja) 2013-04-01 2014-10-09 学校法人 久留米大学 腫瘍抗原ペプチド
GB2530236A (en) 2014-04-11 2016-03-23 Univ Nottingham Trent PAP Peptide analogues
US10654908B2 (en) 2014-04-15 2020-05-19 University Of Virginia Patent Foundation Isolated T cell receptors and methods of use therefor
EP2944652A1 (en) 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
WO2016070928A1 (en) * 2014-11-06 2016-05-12 Orphan Synergy Europe - Pharma Therapeutic multi-peptides t specific immune therapy for treatment of brain metastasis
JP6654207B2 (ja) * 2015-06-29 2020-02-26 オーエスイー・イミュノセラピューティクス 短鎖ペプチド抗腫瘍ワクチンを用いて早期のtメモリー応答を誘発する方法。
SI3573600T1 (sl) 2017-01-25 2022-07-29 Ose Immunotherapeutics Postopek za proizvodnjo obstojne emulzije za dostavo peptida
CA3081774A1 (en) 2017-11-27 2019-05-31 Ose Immunotherapeutics Improved treatment of cancer
CA3122914A1 (en) 2018-12-21 2020-06-25 Ose Immunotherapeutics Bifunctional anti-pd-1/sirp.alpha. molecule
EP3898677A1 (en) 2018-12-21 2021-10-27 OSE Immunotherapeutics Bifunctional anti-pd-1/il-7 molecule
KR102371173B1 (ko) 2018-12-21 2022-03-04 오제 이뮈노테라프틱스 인간화된 항-인간-pd-1 항체
AU2019406453A1 (en) 2018-12-21 2021-07-22 Ose Immunotherapeutics Bifunctional molecule directed against human PD-1

Also Published As

Publication number Publication date
CN114917189B (zh) 2024-05-14
KR102577036B1 (ko) 2023-09-08
AU2018213890B2 (en) 2023-07-20
TW201840331A (zh) 2018-11-16
JP2020505464A (ja) 2020-02-20
EP4029494A1 (en) 2022-07-20
MX2019008878A (es) 2020-02-13
AR113209A1 (es) 2020-02-19
JP7140778B2 (ja) 2022-09-21
PL3573600T3 (pl) 2022-07-11
HUE058717T2 (hu) 2022-09-28
NZ754471A (en) 2023-12-22
SI3573600T1 (sl) 2022-07-29
LT3573600T (lt) 2022-06-27
DK3573600T3 (da) 2022-05-09
IL267237A (en) 2019-08-29
US20220259277A1 (en) 2022-08-18
CA3047492C (en) 2024-01-02
US20190345213A1 (en) 2019-11-14
CN114917189A (zh) 2022-08-19
KR20190107113A (ko) 2019-09-18
ZA201905487B (en) 2020-05-27
TWI793099B (zh) 2023-02-21
WO2018138110A1 (en) 2018-08-02
ES2913268T3 (es) 2022-06-01
BR112019014917A2 (pt) 2020-03-31
RS63259B1 (sr) 2022-06-30
CN110191703B (zh) 2022-04-08
HRP20220605T1 (hr) 2022-07-08
CA3047492A1 (en) 2018-08-02
CN110191703A (zh) 2019-08-30
US11981713B2 (en) 2024-05-14
EP3573600A1 (en) 2019-12-04
US11325959B2 (en) 2022-05-10
AU2018213890A1 (en) 2019-07-04
EP3573600B1 (en) 2022-03-02

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