PT3298162T - Deteção de ácido nucleico alvo e variantes - Google Patents

Deteção de ácido nucleico alvo e variantes

Info

Publication number
PT3298162T
PT3298162T PT167231356T PT16723135T PT3298162T PT 3298162 T PT3298162 T PT 3298162T PT 167231356 T PT167231356 T PT 167231356T PT 16723135 T PT16723135 T PT 16723135T PT 3298162 T PT3298162 T PT 3298162T
Authority
PT
Portugal
Prior art keywords
variants
detection
nucleic acid
target nucleic
target
Prior art date
Application number
PT167231356T
Other languages
English (en)
Original Assignee
Saga Diagnostics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saga Diagnostics Ab filed Critical Saga Diagnostics Ab
Publication of PT3298162T publication Critical patent/PT3298162T/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00Reactions demanding special reaction conditions
    • C12Q2527/107Temperature of melting, i.e. Tm
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00Reactions of nucleic acids characterised by
    • C12Q2531/10Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/107Probe or oligonucleotide ligation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/159Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes
PT167231356T 2015-05-18 2016-05-18 Deteção de ácido nucleico alvo e variantes PT3298162T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1550629 2015-05-18

Publications (1)

Publication Number Publication Date
PT3298162T true PT3298162T (pt) 2020-03-26

Family

ID=56008652

Family Applications (1)

Application Number Title Priority Date Filing Date
PT167231356T PT3298162T (pt) 2015-05-18 2016-05-18 Deteção de ácido nucleico alvo e variantes

Country Status (23)

Country Link
US (2) US11066707B2 (pt)
EP (1) EP3298162B1 (pt)
JP (1) JP6956012B2 (pt)
KR (1) KR102377229B1 (pt)
CN (1) CN107636167B (pt)
AU (1) AU2016263457B2 (pt)
BR (1) BR112017024702A2 (pt)
CA (1) CA2984960C (pt)
CY (1) CY1122788T1 (pt)
DK (1) DK3298162T3 (pt)
EA (1) EA038921B9 (pt)
ES (1) ES2775551T3 (pt)
HR (1) HRP20200321T1 (pt)
HU (1) HUE048349T2 (pt)
IL (1) IL255714B (pt)
LT (1) LT3298162T (pt)
MX (1) MX2017014771A (pt)
PL (1) PL3298162T3 (pt)
PT (1) PT3298162T (pt)
RS (1) RS60032B1 (pt)
SI (1) SI3298162T1 (pt)
WO (1) WO2016184902A1 (pt)
ZA (1) ZA201707740B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020014412A2 (pt) * 2018-01-22 2020-12-29 Luminex Corporation Métodos e composições para análise de fusão discreta
WO2021125854A1 (ko) * 2019-12-20 2021-06-24 고려대학교 산학협력단 극소량의 희귀 단일 염기 변이체 검출용 프라이머 및 이를 이용하여 극소량의 희귀 단일 염기 변이체를 특이적이고 민감하게 검출하는 방법
CN116724124A (zh) * 2020-09-30 2023-09-08 李峰 一种用于dna单核苷酸变异检测的方法、探针及试剂盒及其应用
GB202203187D0 (en) 2022-03-08 2022-04-20 Rarity Bioscience Ab Method of detection of a target nucleic acid sequence
US20230392199A1 (en) 2022-06-03 2023-12-07 Saga Diagnostics Ab Detection of target nucleic acids with preamplification
US20230392212A1 (en) 2022-06-03 2023-12-07 Saga Diagnostics Ab Detection of target nucleic acids
US20240068039A1 (en) 2022-08-31 2024-02-29 Saga Diagnostics Ab Multi-vector detection of variant sequences
WO2024047182A2 (en) 2022-08-31 2024-03-07 Saga Diagnostics Ab Detection of variant esr1 sequences

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US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4351760A (en) 1979-09-07 1982-09-28 Syva Company Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6440706B1 (en) * 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
US6548254B2 (en) 2000-04-28 2003-04-15 Gorilla Genomics, Inc. Methods and compositions for the manufacture of molecular beacons
US6887664B2 (en) * 2000-06-06 2005-05-03 Applera Corporation Asynchronous primed PCR
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
US7198897B2 (en) * 2001-12-19 2007-04-03 Brandeis University Late-PCR
AUPS076902A0 (en) 2002-02-26 2002-03-21 Commonwealth Scientific And Industrial Research Organisation Novel selective polymerase chain reaction
US20040022764A1 (en) * 2002-07-31 2004-02-05 Hanan Polansky Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease
JP4353504B2 (ja) * 2003-05-19 2009-10-28 キヤノン株式会社 核酸の増幅方法および標識化方法、これを用いた核酸検出方法
WO2006094360A1 (en) 2005-03-11 2006-09-14 Molecular Plant Breeding Nominees Ltd Method of amplifying nucleic acid
CA2919210C (en) * 2005-06-07 2019-03-05 Luminex Corporation Methods for detection and typing of nucleic acids
KR101376359B1 (ko) * 2007-08-01 2014-03-27 다나-파버 캔서 인스티튜트 인크. 표적 서열 강화
GB2502409B8 (en) 2008-09-23 2014-10-15 Bio Rad Laboratories Droplet-based assay system
WO2011050278A1 (en) * 2009-10-23 2011-04-28 Eragen Biosciences, Inc. Amplification primers with non-standard bases for increased reaction specificity
EP2614157A4 (en) * 2010-09-08 2014-03-26 Univ Brandeis NUCLEIC ACID DIAGNOSTIC ASSAY COMPOSITIONS AND METHODS FOR VARIABLE SEQUENCE TARGETS
EP2646576B1 (en) * 2010-12-03 2015-10-28 Brandeis University Methods and kits for detecting nucleic acid mutants in wild-type populations
WO2012092259A1 (en) * 2010-12-27 2012-07-05 Ibis Biosciences, Inc. Quantitating high titer samples by digital pcr
EP2691541B1 (en) * 2011-03-31 2017-10-18 Dana-Farber Cancer Institute, Inc. Method for enriching in single-stranded mutant sequences from mixture of wild-type and mutant sequences
WO2012149042A2 (en) * 2011-04-25 2012-11-01 Bio-Rad Laboratories, Inc. Methods and compositions for nucleic acid analysis
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AU2014336987A1 (en) 2013-10-19 2016-04-14 Trovagene, Inc. Detecting mutations in disease over time

Also Published As

Publication number Publication date
IL255714B (en) 2020-09-30
US20220056533A1 (en) 2022-02-24
ZA201707740B (en) 2021-04-28
KR102377229B1 (ko) 2022-03-22
CN107636167A (zh) 2018-01-26
CA2984960C (en) 2022-10-04
CY1122788T1 (el) 2021-05-05
IL255714A (en) 2018-01-31
JP6956012B2 (ja) 2021-10-27
WO2016184902A1 (en) 2016-11-24
HRP20200321T1 (hr) 2020-06-12
US20180340230A1 (en) 2018-11-29
CN107636167B (zh) 2022-09-02
DK3298162T3 (da) 2020-03-02
EA038921B1 (ru) 2021-11-10
PL3298162T3 (pl) 2020-07-27
EP3298162B1 (en) 2019-11-27
MX2017014771A (es) 2018-08-15
HUE048349T2 (hu) 2020-07-28
EP3298162A1 (en) 2018-03-28
EA201792405A1 (ru) 2018-07-31
AU2016263457B2 (en) 2020-08-27
KR20180019585A (ko) 2018-02-26
US11066707B2 (en) 2021-07-20
RS60032B1 (sr) 2020-04-30
LT3298162T (lt) 2020-03-10
CA2984960A1 (en) 2016-11-24
BR112017024702A2 (pt) 2018-09-18
AU2016263457A1 (en) 2017-12-07
EA038921B9 (ru) 2021-12-06
SI3298162T1 (sl) 2020-06-30
JP2018523970A (ja) 2018-08-30
ES2775551T3 (es) 2020-07-27

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