PT3157930T - Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole - Google Patents

Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole

Info

Publication number
PT3157930T
PT3157930T PT15730183T PT15730183T PT3157930T PT 3157930 T PT3157930 T PT 3157930T PT 15730183 T PT15730183 T PT 15730183T PT 15730183 T PT15730183 T PT 15730183T PT 3157930 T PT3157930 T PT 3157930T
Authority
PT
Portugal
Prior art keywords
preparation
methods
heterocyclic compounds
benzodioxole
benzodioxole heterocyclic
Prior art date
Application number
PT15730183T
Other languages
English (en)
Portuguese (pt)
Inventor
Metzler Bjorn
Faldt André
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of PT3157930T publication Critical patent/PT3157930T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT15730183T 2014-06-23 2015-06-22 Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole PT3157930T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14173397 2014-06-23

Publications (1)

Publication Number Publication Date
PT3157930T true PT3157930T (pt) 2018-12-24

Family

ID=50980952

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15730183T PT3157930T (pt) 2014-06-23 2015-06-22 Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole

Country Status (18)

Country Link
US (1) US9908894B2 (en:Method)
EP (1) EP3157930B1 (en:Method)
JP (1) JP6785666B2 (en:Method)
KR (1) KR20170016894A (en:Method)
CN (1) CN106459081B (en:Method)
AU (1) AU2015279428B2 (en:Method)
BR (1) BR112016029510A2 (en:Method)
CA (1) CA2953284A1 (en:Method)
DK (1) DK3157930T3 (en:Method)
ES (1) ES2702451T3 (en:Method)
IL (1) IL249336A0 (en:Method)
MX (1) MX2016016378A (en:Method)
PL (1) PL3157930T3 (en:Method)
PT (1) PT3157930T (en:Method)
RU (1) RU2697251C2 (en:Method)
TW (1) TW201613934A (en:Method)
WO (1) WO2015197534A2 (en:Method)
ZA (1) ZA201608442B (en:Method)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3390407T3 (pl) 2015-12-18 2024-01-29 UNION therapeutics A/S Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu
DK3642210T3 (da) * 2017-06-20 2024-12-09 Union Therapeutics As Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser
EP3724196B9 (en) 2017-12-15 2023-03-22 UNION therapeutics A/S Substituted azetidine dihydrothienopyridines and their use as phosphodiesterase inhibitors
USD914676S1 (en) 2018-05-11 2021-03-30 Samsung Electronics Co., Ltd. Notebook computer
AU2020208761B2 (en) 2019-01-15 2025-03-13 UNION therapeutics A/S Modified release tablet formulations containing phosphodiesterase inhibitors
CA3212316A1 (en) 2021-03-22 2022-09-29 Morten Sommer Treatment of hidradenitis suppurativa with orismilast
GB202205715D0 (en) 2022-04-19 2022-06-01 Union Therapeutics As Treatment of neutrophilic dermatoses
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen
GB202306663D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Combination therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514996B2 (en) * 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
AU705690B2 (en) * 1995-05-19 1999-05-27 Kyowa Hakko Kogyo Co. Ltd. Oxygen-containing heterocyclic compounds
DE10205274A1 (de) * 2002-02-08 2003-08-21 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen
JPWO2004005276A1 (ja) * 2002-07-03 2005-11-04 協和醗酵工業株式会社 1,3−ベンゾジオキソール−2−スピロシクロアルカン誘導体の製造法
WO2008006509A1 (en) * 2006-07-14 2008-01-17 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors
PT2125736E (pt) 2006-12-22 2011-07-01 Leo Pharma As Acetofenonas substituídas úteis como inibidores de pde4
MX2009009238A (es) * 2007-02-28 2009-09-08 Leo Pharma As Nuevos inhibidores de fosfodiesterasa.
UA98639C2 (en) * 2007-02-28 2012-06-11 Лео Фарма А/С Phosphodiesterase inhibitors
SI2585469T1 (sl) * 2010-06-24 2016-11-30 Leo Pharma A/S Heterociklične spojine benzodioksola ali benzodioksepina kot zaviralci fostodiesteraze
WO2014096018A1 (en) * 2012-12-19 2014-06-26 Leo Pharma A/S Methods for the preparation of substituted acetophenones
PL3390407T3 (pl) * 2015-12-18 2024-01-29 UNION therapeutics A/S Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu

Also Published As

Publication number Publication date
RU2697251C2 (ru) 2019-08-13
DK3157930T3 (en) 2019-01-21
JP2017520547A (ja) 2017-07-27
CN106459081A (zh) 2017-02-22
MX2016016378A (es) 2017-10-16
EP3157930B1 (en) 2018-10-17
RU2017101808A (ru) 2018-07-27
TW201613934A (en) 2016-04-16
KR20170016894A (ko) 2017-02-14
AU2015279428B2 (en) 2018-02-15
RU2017101808A3 (en:Method) 2019-01-22
EP3157930A2 (en) 2017-04-26
ES2702451T3 (es) 2019-03-01
WO2015197534A3 (en) 2016-03-17
PL3157930T3 (pl) 2019-04-30
ZA201608442B (en) 2018-05-30
IL249336A0 (en) 2017-02-28
AU2015279428A1 (en) 2017-01-05
WO2015197534A2 (en) 2015-12-30
CN106459081B (zh) 2019-09-10
BR112016029510A2 (pt) 2017-08-22
US9908894B2 (en) 2018-03-06
CA2953284A1 (en) 2015-12-30
US20170137438A1 (en) 2017-05-18
JP6785666B2 (ja) 2020-11-18

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