PT3140287T - Novo sal de ivabradina e um processo para a sua preparação - Google Patents

Novo sal de ivabradina e um processo para a sua preparação

Info

Publication number
PT3140287T
PT3140287T PT157258278T PT15725827T PT3140287T PT 3140287 T PT3140287 T PT 3140287T PT 157258278 T PT157258278 T PT 157258278T PT 15725827 T PT15725827 T PT 15725827T PT 3140287 T PT3140287 T PT 3140287T
Authority
PT
Portugal
Prior art keywords
new
preparation process
ivabradine
salt
ivabradine salt
Prior art date
Application number
PT157258278T
Other languages
English (en)
Inventor
Lynch Michael
Cointepas Patrick
Lafargue David
Briault Gilles
Original Assignee
Les Laboratoires Servier Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier Sas filed Critical Les Laboratoires Servier Sas
Publication of PT3140287T publication Critical patent/PT3140287T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT157258278T 2014-05-06 2015-05-06 Novo sal de ivabradina e um processo para a sua preparação PT3140287T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1454081A FR3020810B1 (fr) 2014-05-06 2014-05-06 Nouveau sel de l'ivabradine et son procede de preparation.

Publications (1)

Publication Number Publication Date
PT3140287T true PT3140287T (pt) 2018-03-22

Family

ID=51518916

Family Applications (1)

Application Number Title Priority Date Filing Date
PT157258278T PT3140287T (pt) 2014-05-06 2015-05-06 Novo sal de ivabradina e um processo para a sua preparação

Country Status (21)

Country Link
US (1) US9856221B2 (pt)
EP (1) EP3140287B1 (pt)
JP (1) JP2017514848A (pt)
CN (1) CN106458915B (pt)
AU (1) AU2015257518B2 (pt)
CA (1) CA2947475C (pt)
CY (1) CY1120402T1 (pt)
DK (1) DK3140287T3 (pt)
ES (1) ES2672927T3 (pt)
FR (1) FR3020810B1 (pt)
HR (1) HRP20180716T1 (pt)
HU (1) HUE037755T2 (pt)
LT (1) LT3140287T (pt)
MA (1) MA39756B1 (pt)
ME (1) ME03062B (pt)
NO (1) NO3140287T3 (pt)
PL (1) PL3140287T3 (pt)
PT (1) PT3140287T (pt)
RS (1) RS57147B1 (pt)
SI (1) SI3140287T1 (pt)
WO (1) WO2015170053A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI784370B (zh) 2017-01-31 2022-11-21 美商基利科學股份有限公司 替諾福韋埃拉酚胺(tenofovir alafenamide)之晶型

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
FR2681862B1 (fr) * 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
PT2594272T (pt) * 2005-05-18 2018-07-31 Horizon Orphan Llc Fluoroquinolonas aerossolizadas e suas utilizações
WO2007064845A1 (en) * 2005-11-29 2007-06-07 Pr Pharmaceuticals, Inc. Sustained release butorphanol drug delivery compositions for analgesia
US20080293695A1 (en) * 2007-05-22 2008-11-27 David William Bristol Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
US8653106B2 (en) * 2010-07-30 2014-02-18 Pisgah Laboratories, Inc. Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
FR2920773B1 (fr) * 2007-09-11 2009-10-23 Servier Lab Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2012102247A (ru) * 2009-06-24 2013-07-27 Мсд Осс Б.В. Инъекционные композиции, содержащие асенапин и способ лечения с их применением
WO2011104723A2 (en) * 2010-02-23 2011-09-01 Ind-Swift Laboratories Limited Acid addition salts of ivabradine and preparation thereof
US20130116239A1 (en) * 2010-06-14 2013-05-09 ratiopharm GnbH Ivabradine-containing pharmaceutical composition with modified release
FR2961105B1 (fr) * 2010-06-15 2013-02-08 Servier Lab Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque
ES2564973T3 (es) * 2011-04-26 2016-03-30 Torrent Pharmaceuticals Limited Sales por adición de ácidos de risperidona y composiciones farmacéuticas de las mismas
CN102908327B (zh) * 2011-08-05 2015-03-11 江苏恒瑞医药股份有限公司 伊伐布雷定或其可药用盐的缓释制剂
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects

Also Published As

Publication number Publication date
US20170050932A1 (en) 2017-02-23
ES2672927T3 (es) 2018-06-18
ME03062B (me) 2019-01-20
AU2015257518A1 (en) 2016-11-03
LT3140287T (lt) 2018-04-10
CA2947475A1 (fr) 2015-11-12
WO2015170053A1 (fr) 2015-11-12
MA39756B1 (fr) 2018-05-31
FR3020810B1 (fr) 2016-05-06
CN106458915A (zh) 2017-02-22
US9856221B2 (en) 2018-01-02
MA39756A (fr) 2018-03-07
AU2015257518B2 (en) 2018-12-13
HRP20180716T1 (hr) 2018-06-15
FR3020810A1 (fr) 2015-11-13
CN106458915B (zh) 2019-05-07
PL3140287T3 (pl) 2018-07-31
SI3140287T1 (en) 2018-05-31
EP3140287A1 (fr) 2017-03-15
CA2947475C (fr) 2018-07-10
HUE037755T2 (hu) 2018-09-28
EP3140287B1 (fr) 2018-03-07
DK3140287T3 (en) 2018-06-14
JP2017514848A (ja) 2017-06-08
CY1120402T1 (el) 2019-07-10
RS57147B1 (sr) 2018-07-31
NO3140287T3 (pt) 2018-08-04

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