PT3107917T - Macrociclos de pirazolopirimidina como inibidores da replicação do vírus da imunodeficiência humana - Google Patents
Macrociclos de pirazolopirimidina como inibidores da replicação do vírus da imunodeficiência humanaInfo
- Publication number
- PT3107917T PT3107917T PT14709808T PT14709808T PT3107917T PT 3107917 T PT3107917 T PT 3107917T PT 14709808 T PT14709808 T PT 14709808T PT 14709808 T PT14709808 T PT 14709808T PT 3107917 T PT3107917 T PT 3107917T
- Authority
- PT
- Portugal
- Prior art keywords
- macrocycles
- pyrazolopyrimidine
- inhibitors
- immunodeficiency virus
- human immunodeficiency
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2014/017070 WO2015126376A1 (en) | 2014-02-19 | 2014-02-19 | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| EP14709808.1A EP3107917B1 (en) | 2014-02-19 | 2014-02-19 | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3107917T true PT3107917T (pt) | 2018-11-13 |
Family
ID=50272724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT14709808T PT3107917T (pt) | 2014-02-19 | 2014-02-19 | Macrociclos de pirazolopirimidina como inibidores da replicação do vírus da imunodeficiência humana |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10125148B2 (pt) |
| EP (1) | EP3107917B1 (pt) |
| ES (1) | ES2687893T3 (pt) |
| PT (1) | PT3107917T (pt) |
| WO (1) | WO2015126376A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015126743A1 (en) * | 2014-02-18 | 2015-08-27 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8633200B2 (en) * | 2010-09-08 | 2014-01-21 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| US8906929B2 (en) | 2012-08-16 | 2014-12-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2015126743A1 (en) | 2014-02-18 | 2015-08-27 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
-
2014
- 2014-02-19 ES ES14709808.1T patent/ES2687893T3/es active Active
- 2014-02-19 PT PT14709808T patent/PT3107917T/pt unknown
- 2014-02-19 WO PCT/US2014/017070 patent/WO2015126376A1/en active Application Filing
- 2014-02-19 US US15/119,475 patent/US10125148B2/en not_active Expired - Fee Related
- 2014-02-19 EP EP14709808.1A patent/EP3107917B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2687893T3 (es) | 2018-10-29 |
| US20170008909A1 (en) | 2017-01-12 |
| EP3107917A1 (en) | 2016-12-28 |
| US10125148B2 (en) | 2018-11-13 |
| EP3107917B1 (en) | 2018-08-15 |
| WO2015126376A1 (en) | 2015-08-27 |
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