PT2755765T - Dispositivo microfluídico para geração de uma sequência de substâncias num canal microfluídico - Google Patents

Dispositivo microfluídico para geração de uma sequência de substâncias num canal microfluídico

Info

Publication number
PT2755765T
PT2755765T PT127662971T PT12766297T PT2755765T PT 2755765 T PT2755765 T PT 2755765T PT 127662971 T PT127662971 T PT 127662971T PT 12766297 T PT12766297 T PT 12766297T PT 2755765 T PT2755765 T PT 2755765T
Authority
PT
Portugal
Prior art keywords
microfluidic device
microfluidic
Prior art date
Application number
PT127662971T
Other languages
English (en)
Original Assignee
European Molecular Biology Laboratory Embl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by European Molecular Biology Laboratory Embl filed Critical European Molecular Biology Laboratory Embl
Publication of PT2755765T publication Critical patent/PT2755765T/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/061—Counting droplets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0694—Creating chemical gradients in a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J2003/466—Coded colour; Recognition of predetermined colour; Determining proximity to predetermined colour
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/4673—Plural tanks or compartments with parallel flow
    • Y10T137/469—Sequentially filled and emptied [e.g., holding type]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/877—With flow control means for branched passages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
PT127662971T 2011-09-14 2012-09-14 Dispositivo microfluídico para geração de uma sequência de substâncias num canal microfluídico PT2755765T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161534529P 2011-09-14 2011-09-14
GB201115895A GB201115895D0 (en) 2011-09-14 2011-09-14 Microfluidic device

Publications (1)

Publication Number Publication Date
PT2755765T true PT2755765T (pt) 2020-10-08

Family

ID=44908571

Family Applications (1)

Application Number Title Priority Date Filing Date
PT127662971T PT2755765T (pt) 2011-09-14 2012-09-14 Dispositivo microfluídico para geração de uma sequência de substâncias num canal microfluídico

Country Status (8)

Country Link
US (3) US9810607B2 (pt)
EP (1) EP2755765B1 (pt)
CA (2) CA2844544C (pt)
DK (1) DK2755765T3 (pt)
ES (1) ES2820450T3 (pt)
GB (1) GB201115895D0 (pt)
PT (1) PT2755765T (pt)
WO (1) WO2013037962A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201115895D0 (en) 2011-09-14 2011-10-26 Embl Microfluidic device
GB201306444D0 (en) 2013-04-09 2013-05-22 Base4 Innovation Ltd Single nucleotide detection method
CN103433085B (zh) * 2013-08-23 2015-04-22 许毅 自动切换通道的纸基微流体装置及其应用
ES2860938T3 (es) * 2014-09-25 2021-10-05 European Molecular Biology Laboratory Dispositivo microfluídico para la generación de muestras combinatorias
JP7257334B2 (ja) 2017-05-15 2023-04-13 ライトキャスト ディスカバリー リミテッド 単一ヌクレオチド検出方法および関連するプローブ
WO2018226876A1 (en) 2017-06-06 2018-12-13 The Regents Of The University Of California Systems and methods for rapid generation of droplet libraries
US11919000B2 (en) 2019-10-10 2024-03-05 1859, Inc. Methods and systems for microfluidic screening

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1252428B (pt) 1965-12-03 1900-01-01
US4601881A (en) 1984-11-01 1986-07-22 Allied Corporation Liquid handling system
JP3990909B2 (ja) 2001-12-26 2007-10-17 旭化成株式会社 化学反応用カートリッジ
US7718099B2 (en) 2002-04-25 2010-05-18 Tosoh Corporation Fine channel device, fine particle producing method and solvent extraction method
US7901939B2 (en) 2002-05-09 2011-03-08 University Of Chicago Method for performing crystallization and reactions in pressure-driven fluid plugs
ES2327231T3 (es) 2003-03-10 2009-10-27 The Regents Of The University Of Michigan Control microfluidico integrado que emplea accionadores tactiles programables.
JP2007163459A (ja) 2005-11-18 2007-06-28 Sharp Corp 分析用マイクロチップ
EP2363205A3 (en) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
EP3335782B1 (en) * 2006-05-11 2020-09-09 Bio-Rad Laboratories, Inc. Microfluidic devices
FR2907228B1 (fr) 2006-10-13 2009-07-24 Rhodia Recherches & Tech Dispositif d'ecoulement fluidique,ensemble de determination d'au moins une caracteristique d'un systeme physico-chimique comprenant un tel dispositif,procede de determination et procede de criblage correspondants
WO2008097559A2 (en) * 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
EP2008716A1 (en) 2007-06-28 2008-12-31 Bp Oil International Limited Sample plate
US8062903B2 (en) 2008-03-03 2011-11-22 University Of Washington Droplet compartmentalization for chemical separation and on-line sampling
US9011777B2 (en) 2008-03-21 2015-04-21 Lawrence Livermore National Security, Llc Monodisperse microdroplet generation and stopping without coalescence
JP2009276135A (ja) 2008-05-13 2009-11-26 Seiko Epson Corp 生体物質検出カートリッジ、生体物質検出装置、および生体物質検出方法
DE102008031798A1 (de) 2008-07-04 2010-01-07 Bürkert Werke GmbH & Co. KG Verfahren zur Übermittlung von Informationen
US20110114190A1 (en) 2009-11-16 2011-05-19 The Hong Kong University Of Science And Technology Microfluidic droplet generation and/or manipulation with electrorheological fluid
BRPI1106097A2 (pt) 2010-01-24 2017-06-27 Inst Chemy Fizycznej Polskiej Akademi Nauk sistema e método para produção e manipulação automazitada de misturas liquidas
EP2550528B1 (en) 2010-03-25 2019-09-11 Bio-Rad Laboratories, Inc. Droplet generation for droplet-based assays
EP2436444A1 (en) 2010-10-01 2012-04-04 Centre National de la Recherche Scientifique (C.N.R.S.) Microfluidic device for production and collection of droplets of a fluid
GB201115895D0 (en) 2011-09-14 2011-10-26 Embl Microfluidic device

Also Published As

Publication number Publication date
US10215671B2 (en) 2019-02-26
EP2755765A2 (en) 2014-07-23
EP2755765B1 (en) 2020-07-22
CA2844544A1 (en) 2013-03-21
ES2820450T3 (es) 2021-04-21
CA3114427C (en) 2023-08-01
US11371917B2 (en) 2022-06-28
US20180095014A1 (en) 2018-04-05
US20140332083A1 (en) 2014-11-13
WO2013037962A2 (en) 2013-03-21
DK2755765T3 (da) 2020-09-21
CA3114427A1 (en) 2013-03-21
WO2013037962A3 (en) 2013-05-30
CA2844544C (en) 2021-05-25
GB201115895D0 (en) 2011-10-26
US9810607B2 (en) 2017-11-07
US20190154552A1 (en) 2019-05-23

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