PT2688578T - Inibidores de mia (atividade inibitória de melanoma) para prevenir e curar vitiligo - Google Patents

Inibidores de mia (atividade inibitória de melanoma) para prevenir e curar vitiligo

Info

Publication number
PT2688578T
PT2688578T PT12710120T PT12710120T PT2688578T PT 2688578 T PT2688578 T PT 2688578T PT 12710120 T PT12710120 T PT 12710120T PT 12710120 T PT12710120 T PT 12710120T PT 2688578 T PT2688578 T PT 2688578T
Authority
PT
Portugal
Prior art keywords
mia
inhibitors
preventing
detecting
inhibitory activity
Prior art date
Application number
PT12710120T
Other languages
English (en)
Inventor
Bordignon Matteo
Original Assignee
Bordignon Matteo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bordignon Matteo filed Critical Bordignon Matteo
Publication of PT2688578T publication Critical patent/PT2688578T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/20—Dermatological disorders
    • G01N2800/207—Pigmentation disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT12710120T 2011-03-22 2012-03-12 Inibidores de mia (atividade inibitória de melanoma) para prevenir e curar vitiligo PT2688578T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000134A ITRM20110134A1 (it) 2011-03-22 2011-03-22 Inibitori di mia (attività inibitoria melanoma) per identificare, prevenire e curare la vitiligine

Publications (1)

Publication Number Publication Date
PT2688578T true PT2688578T (pt) 2019-05-08

Family

ID=43977364

Family Applications (1)

Application Number Title Priority Date Filing Date
PT12710120T PT2688578T (pt) 2011-03-22 2012-03-12 Inibidores de mia (atividade inibitória de melanoma) para prevenir e curar vitiligo

Country Status (15)

Country Link
US (1) US20140004130A1 (pt)
EP (1) EP2688578B1 (pt)
JP (1) JP2014514285A (pt)
KR (1) KR20140041466A (pt)
CN (1) CN103930122A (pt)
AU (1) AU2012232753A1 (pt)
BR (1) BR112013024301A2 (pt)
DK (1) DK2688578T3 (pt)
ES (1) ES2730704T3 (pt)
IT (1) ITRM20110134A1 (pt)
MX (1) MX2013010891A (pt)
PL (1) PL2688578T3 (pt)
PT (1) PT2688578T (pt)
RU (1) RU2013147195A (pt)
WO (1) WO2012127352A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018117613A1 (ko) * 2016-12-19 2018-06-28 한미약품 주식회사 뇌 표적 지속성 단백질 결합체
EP3936138A1 (en) 2020-07-09 2022-01-12 Bella Aurora Labs, S.A. Pharmaceutical composition for the treatment of vitiligo
EP4292581A1 (en) 2022-06-16 2023-12-20 Bella Aurora Labs, S.A. Hair repigmenting composition
EP4385515A1 (en) 2022-12-16 2024-06-19 Bella Aurora Labs, S.A. Composition for skin repigmentation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7531294A (en) * 1993-07-20 1995-02-20 Boehringer Mannheim Gmbh Melanoma-inhibiting protein
DE19653358A1 (de) * 1996-12-20 1998-06-25 Boehringer Mannheim Gmbh Immunoassay zum Nachweis von MIA
WO2001070253A1 (en) * 2000-03-23 2001-09-27 Akzo Nobel N.V. Use of mia in immunotherapy
WO2003064457A1 (en) * 2002-01-29 2003-08-07 Antisense Pharma Gmbh A method for inhibiting 'melanoma inhibitory activity' mia
JP4649408B2 (ja) * 2003-08-12 2011-03-09 アンティセンス ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング 「黒色腫阻害活性（ｍｉａ）」を阻害するアンチセンスオリゴヌクレオチド
WO2013033395A1 (en) * 2011-08-30 2013-03-07 Loyola University Chicago MUTANT HSP70i TO PREVENT AUTOIMMUNE DISEASE

Also Published As

Publication number Publication date
PL2688578T3 (pl) 2019-07-31
BR112013024301A2 (pt) 2018-04-17
WO2012127352A8 (en) 2014-03-13
EP2688578A2 (en) 2014-01-29
EP2688578B1 (en) 2019-03-27
RU2013147195A (ru) 2015-04-27
AU2012232753A1 (en) 2014-01-23
CN103930122A (zh) 2014-07-16
ES2730704T3 (es) 2019-11-12
ITRM20110134A1 (it) 2012-09-23
WO2012127352A3 (en) 2012-12-27
MX2013010891A (es) 2014-03-12
DK2688578T3 (da) 2019-06-11
JP2014514285A (ja) 2014-06-19
WO2012127352A2 (en) 2012-09-27
US20140004130A1 (en) 2014-01-02
KR20140041466A (ko) 2014-04-04

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