PT2567976T - Anticorpos contra cd38 para tratamento do mieloma múltiplo - Google Patents

Anticorpos contra cd38 para tratamento do mieloma múltiplo Download PDF

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Publication number
PT2567976T
PT2567976T PT121787782T PT12178778T PT2567976T PT 2567976 T PT2567976 T PT 2567976T PT 121787782 T PT121787782 T PT 121787782T PT 12178778 T PT12178778 T PT 12178778T PT 2567976 T PT2567976 T PT 2567976T
Authority
PT
Portugal
Prior art keywords
antibody
seq
human
sequence
cell
Prior art date
Application number
PT121787782T
Other languages
English (en)
Portuguese (pt)
Inventor
De Weers Michel
Graus Yvo
Parren Paul
Van Vugt Martine
De Winkel Janvan
Oprins Judith
Original Assignee
Genmab As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genmab As filed Critical Genmab As
Publication of PT2567976T publication Critical patent/PT2567976T/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT121787782T 2005-03-23 2006-03-23 Anticorpos contra cd38 para tratamento do mieloma múltiplo PT2567976T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200500429 2005-03-23
US66757905P 2005-04-01 2005-04-01
US69616305P 2005-07-01 2005-07-01
US72856105P 2005-10-20 2005-10-20

Publications (1)

Publication Number Publication Date
PT2567976T true PT2567976T (pt) 2017-10-19

Family

ID=50644285

Family Applications (2)

Application Number Title Priority Date Filing Date
PT121787782T PT2567976T (pt) 2005-03-23 2006-03-23 Anticorpos contra cd38 para tratamento do mieloma múltiplo
PT67228619T PT1866338T (pt) 2005-03-23 2006-03-23 Anticorpos contra cd38 para tratamento do mieloma múltiplo

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT67228619T PT1866338T (pt) 2005-03-23 2006-03-23 Anticorpos contra cd38 para tratamento do mieloma múltiplo

Country Status (12)

Country Link
KR (1) KR20140033240A (cg-RX-API-DMAC7.html)
BE (1) BE2017C062I2 (cg-RX-API-DMAC7.html)
DK (1) DK1866338T3 (cg-RX-API-DMAC7.html)
ES (2) ES2644982T3 (cg-RX-API-DMAC7.html)
HU (2) HUE030783T2 (cg-RX-API-DMAC7.html)
LT (2) LT1866338T (cg-RX-API-DMAC7.html)
NZ (2) NZ600059A (cg-RX-API-DMAC7.html)
PL (1) PL1866338T3 (cg-RX-API-DMAC7.html)
PT (2) PT2567976T (cg-RX-API-DMAC7.html)
RS (1) RS55442B1 (cg-RX-API-DMAC7.html)
SG (1) SG10201610317VA (cg-RX-API-DMAC7.html)
UA (2) UA116520C2 (cg-RX-API-DMAC7.html)

Also Published As

Publication number Publication date
ES2606762T3 (es) 2017-03-27
KR20140033240A (ko) 2014-03-17
RS55442B1 (sr) 2017-04-28
LT2567976T (lt) 2017-12-11
PT1866338T (pt) 2016-12-14
HUE030783T2 (en) 2017-06-28
HUE034962T2 (en) 2018-03-28
NZ625944A (en) 2016-01-29
ES2644982T3 (es) 2017-12-01
BE2017C062I2 (cg-RX-API-DMAC7.html) 2025-12-03
UA116520C2 (uk) 2018-04-10
PL1866338T3 (pl) 2017-04-28
UA98756C2 (ru) 2012-06-25
SG10201610317VA (en) 2017-02-27
LT1866338T (lt) 2017-01-25
DK1866338T3 (da) 2017-01-02
NZ600059A (en) 2016-01-29

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