PT2556826T - Formulação de multiparticulada de libertação modificada de diltiazem hcl - Google Patents

Formulação de multiparticulada de libertação modificada de diltiazem hcl

Info

Publication number
PT2556826T
PT2556826T PT121794267T PT12179426T PT2556826T PT 2556826 T PT2556826 T PT 2556826T PT 121794267 T PT121794267 T PT 121794267T PT 12179426 T PT12179426 T PT 12179426T PT 2556826 T PT2556826 T PT 2556826T
Authority
PT
Portugal
Prior art keywords
modified
multiparticulate formulation
diltiazem hcl
release multiparticulate
diltiazem
Prior art date
Application number
PT121794267T
Other languages
English (en)
Inventor
Valducci Roberto
Alighieri Tiziano
Avanessian Serozh
Original Assignee
Valpharma S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valpharma S P A filed Critical Valpharma S P A
Publication of PT2556826T publication Critical patent/PT2556826T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
PT121794267T 2011-08-08 2012-08-06 Formulação de multiparticulada de libertação modificada de diltiazem hcl PT2556826T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000172A ITFI20110172A1 (it) 2011-08-08 2011-08-08 Formulazione multiparticolata a rilascio modificato di diltiazem hcl.

Publications (1)

Publication Number Publication Date
PT2556826T true PT2556826T (pt) 2016-12-28

Family

ID=44720953

Family Applications (1)

Application Number Title Priority Date Filing Date
PT121794267T PT2556826T (pt) 2011-08-08 2012-08-06 Formulação de multiparticulada de libertação modificada de diltiazem hcl

Country Status (4)

Country Link
EP (1) EP2556826B1 (pt)
ES (1) ES2607585T3 (pt)
IT (1) ITFI20110172A1 (pt)
PT (1) PT2556826T (pt)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622716A (en) 1987-02-20 1997-04-22 Farmarc Nederland B.V. Process for preparing a retard product containing diltiazem for a single daily administration
US5344657A (en) 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
US5288505A (en) 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
US5834024A (en) 1995-01-05 1998-11-10 Fh Faulding & Co. Limited Controlled absorption diltiazem pharmaceutical formulation
US5567441A (en) 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
FR2742660B1 (fr) 1995-12-22 1998-04-03 Ethypharm Lab Prod Ethiques Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
WO2000024423A1 (fr) * 1998-10-26 2000-05-04 Tanabe Seiyaku Co., Ltd. Particules a liberation prolongee
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
WO2005016317A1 (en) 2003-08-19 2005-02-24 Themis Laboratories Private Limited Process for manufacture of extended release pellets containing diltiazem hci

Also Published As

Publication number Publication date
EP2556826A1 (en) 2013-02-13
ITFI20110172A1 (it) 2013-02-09
EP2556826B1 (en) 2016-09-21
ES2607585T3 (es) 2017-04-03

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