PT2549984E - Formulações farmacêuticas de dupla camada contendo agonistas e antagonistas opioides - Google Patents
Formulações farmacêuticas de dupla camada contendo agonistas e antagonistas opioides Download PDFInfo
- Publication number
- PT2549984E PT2549984E PT117161893T PT11716189T PT2549984E PT 2549984 E PT2549984 E PT 2549984E PT 117161893 T PT117161893 T PT 117161893T PT 11716189 T PT11716189 T PT 11716189T PT 2549984 E PT2549984 E PT 2549984E
- Authority
- PT
- Portugal
- Prior art keywords
- antagonists
- double
- pharmaceutical formulations
- formulations containing
- opioid agonists
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI2010A000047A IT1398930B1 (it) | 2010-03-24 | 2010-03-24 | Formulazioni farmaceutiche bistrato contenenti agonisti ed antagonisti oppioidi. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2549984E true PT2549984E (pt) | 2015-07-24 |
Family
ID=42830655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT117161893T PT2549984E (pt) | 2010-03-24 | 2011-03-23 | Formulações farmacêuticas de dupla camada contendo agonistas e antagonistas opioides |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20130011479A1 (pt) |
| EP (1) | EP2549984B1 (pt) |
| CN (1) | CN102858324A (pt) |
| AU (1) | AU2011231638B2 (pt) |
| BR (1) | BR112012024139A2 (pt) |
| CA (1) | CA2794221A1 (pt) |
| ES (1) | ES2539391T3 (pt) |
| IT (1) | IT1398930B1 (pt) |
| MX (1) | MX2012010667A (pt) |
| PL (1) | PL2549984T3 (pt) |
| PT (1) | PT2549984E (pt) |
| RU (1) | RU2012145095A (pt) |
| WO (1) | WO2011117306A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004031096D1 (de) | 2003-03-26 | 2011-03-03 | Egalet As | Morphin-system mit kontrollierter freisetzung |
| AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
| EP2919903B1 (en) | 2012-11-14 | 2020-07-22 | W.R. Grace & CO. - CONN. | Compositions containing a biologically active material and a non-ordered inorganic oxide |
| US8637538B1 (en) | 2012-12-14 | 2014-01-28 | Trevi Therapeutics, Inc. | Methods for treatment of pruritis |
| US8987289B2 (en) | 2012-12-14 | 2015-03-24 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US20140179727A1 (en) | 2012-12-14 | 2014-06-26 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10105360B2 (en) | 2013-12-11 | 2018-10-23 | Develco Pharma Schweiz Ag | Method and composition for the treatment of opioid induced constipation |
| WO2015086528A1 (de) | 2013-12-11 | 2015-06-18 | Develco Pharma Schweiz Ag | Naloxon-monopräparat und mehrschichttablette |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9707184B2 (en) | 2014-07-17 | 2017-07-18 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| CA2964628A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| EP3229785A2 (de) * | 2014-12-08 | 2017-10-18 | Develco Pharma Schweiz AG | Naloxon-monopräparat und mehrschichttablette |
| US20160256451A1 (en) | 2015-03-06 | 2016-09-08 | Develco Pharma Schweiz Ag | Dosage of naloxone |
| CA2980328A1 (en) | 2015-04-02 | 2016-10-06 | Theravance Biopharma R&D Ip, Llc | Combination dosage form of a mu opioid receptor antagonist and an opioid agent |
| WO2016193456A2 (en) | 2015-06-03 | 2016-12-08 | Develco Pharma Schweiz Ag | Opioid receptor antagonist for use in treating patients with severe constipation |
| EP3290027A1 (en) | 2016-09-02 | 2018-03-07 | Develco Pharma Schweiz AG | Method and composition for the treatment of opioid induced constipation |
| AU2019309913A1 (en) | 2018-07-23 | 2021-03-11 | Trevi Therapeutics, Inc. | Treatment of chronic cough, breathlessness and dyspnea |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US5512578A (en) * | 1992-09-21 | 1996-04-30 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opiod agonists |
| US5580876A (en) | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| DE4325465B4 (de) * | 1993-07-29 | 2004-03-04 | Zenz, Michael, Prof. Dr.med. | Orales pharmazeutisches Präparat für die Schmerztherapie |
| AU2059297A (en) * | 1996-03-12 | 1997-10-01 | Alza Corporation | Composition and dosage form comprising opioid antagonist |
| PL357158A1 (en) | 2000-02-08 | 2004-07-12 | Euro-Celtique, S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| DE10250088A1 (de) * | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20050245557A1 (en) | 2003-10-15 | 2005-11-03 | Pain Therapeutics, Inc. | Methods and materials useful for the treatment of arthritic conditions, inflammation associated with a chronic condition or chronic pain |
| US20060009478A1 (en) * | 2003-10-15 | 2006-01-12 | Nadav Friedmann | Methods for the treatment of back pain |
-
2010
- 2010-03-24 IT ITFI2010A000047A patent/IT1398930B1/it active
-
2011
- 2011-03-23 MX MX2012010667A patent/MX2012010667A/es active IP Right Grant
- 2011-03-23 ES ES11716189.3T patent/ES2539391T3/es active Active
- 2011-03-23 CA CA2794221A patent/CA2794221A1/en not_active Abandoned
- 2011-03-23 US US13/636,243 patent/US20130011479A1/en not_active Abandoned
- 2011-03-23 BR BR112012024139A patent/BR112012024139A2/pt active Search and Examination
- 2011-03-23 PL PL11716189T patent/PL2549984T3/pl unknown
- 2011-03-23 CN CN2011800137742A patent/CN102858324A/zh active Pending
- 2011-03-23 RU RU2012145095/15A patent/RU2012145095A/ru not_active Application Discontinuation
- 2011-03-23 EP EP11716189.3A patent/EP2549984B1/en active Active
- 2011-03-23 WO PCT/EP2011/054463 patent/WO2011117306A1/en active Application Filing
- 2011-03-23 PT PT117161893T patent/PT2549984E/pt unknown
- 2011-03-23 AU AU2011231638A patent/AU2011231638B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011117306A1 (en) | 2011-09-29 |
| US20130011479A1 (en) | 2013-01-10 |
| AU2011231638B2 (en) | 2016-05-12 |
| IT1398930B1 (it) | 2013-03-28 |
| ES2539391T3 (es) | 2015-06-30 |
| BR112012024139A2 (pt) | 2017-03-01 |
| CA2794221A1 (en) | 2011-09-29 |
| MX2012010667A (es) | 2012-11-09 |
| RU2012145095A (ru) | 2014-04-27 |
| PL2549984T3 (pl) | 2015-08-31 |
| EP2549984B1 (en) | 2015-03-18 |
| EP2549984A1 (en) | 2013-01-30 |
| CN102858324A (zh) | 2013-01-02 |
| AU2011231638A1 (en) | 2012-11-08 |
| ITFI20100047A1 (it) | 2011-09-25 |
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