PT2069395E - Novos antigénios e anticorpos associados a adenocarcinoma ductal do pâncreas - Google Patents

Novos antigénios e anticorpos associados a adenocarcinoma ductal do pâncreas Download PDF

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Publication number
PT2069395E
PT2069395E PT07820692T PT07820692T PT2069395E PT 2069395 E PT2069395 E PT 2069395E PT 07820692 T PT07820692 T PT 07820692T PT 07820692 T PT07820692 T PT 07820692T PT 2069395 E PT2069395 E PT 2069395E
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PT
Portugal
Prior art keywords
pda
antibodies
enoa
isoforms
ala
Prior art date
Application number
PT07820692T
Other languages
English (en)
Portuguese (pt)
Inventor
Francesco Novelli
Barbara Tomaino
Paola Cappello
Original Assignee
Ribovax Biotechnologies Sa
Bioline Diagnostici Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribovax Biotechnologies Sa, Bioline Diagnostici Srl filed Critical Ribovax Biotechnologies Sa
Publication of PT2069395E publication Critical patent/PT2069395E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57438Specifically defined cancers of liver, pancreas or kidney
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/01011Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/988Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
PT07820692T 2006-09-29 2007-09-28 Novos antigénios e anticorpos associados a adenocarcinoma ductal do pâncreas PT2069395E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121552 2006-09-29
EP06126726 2006-12-20

Publications (1)

Publication Number Publication Date
PT2069395E true PT2069395E (pt) 2012-04-27

Family

ID=38895810

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07820692T PT2069395E (pt) 2006-09-29 2007-09-28 Novos antigénios e anticorpos associados a adenocarcinoma ductal do pâncreas

Country Status (18)

Country Link
US (1) US8071721B2 (OSRAM)
EP (1) EP2069395B1 (OSRAM)
JP (1) JP2010505104A (OSRAM)
KR (1) KR20090094227A (OSRAM)
CN (1) CN101578295B (OSRAM)
AT (1) ATE542831T1 (OSRAM)
AU (1) AU2007301966B2 (OSRAM)
BR (1) BRPI0717282A2 (OSRAM)
CA (1) CA2664841A1 (OSRAM)
DK (1) DK2069395T3 (OSRAM)
EA (1) EA016731B1 (OSRAM)
ES (1) ES2381304T3 (OSRAM)
IL (2) IL197868A (OSRAM)
NO (1) NO20091662L (OSRAM)
NZ (1) NZ576409A (OSRAM)
PL (1) PL2069395T3 (OSRAM)
PT (1) PT2069395E (OSRAM)
WO (1) WO2008037792A1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102171569A (zh) * 2008-05-09 2011-08-31 杜克大学 检测和治疗癌症的自身抗体
IT1398782B1 (it) 2009-09-11 2013-03-18 Novelli Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.
ITTO20120523A1 (it) * 2012-06-15 2013-12-16 Natimab Therapeutics S R L Procedimento e kit per la diagnosi in vitro dell'adenocarcinoma duttale pancreatico o per determinare la predisposizione all'adenocarcinoma duttale pancreatico
RU2656153C1 (ru) * 2013-12-20 2018-05-31 Девелопмент Сентер Фор Байотекнолоджи Антитела, специфичные к альфа-энолазе, и способы применения в противоопухолевой терапии
CN106659766B (zh) 2014-01-13 2025-03-28 博格有限责任公司 烯醇酶1(eno1)组合物及其用途
CN115786317A (zh) * 2022-12-12 2023-03-14 江苏三联生物工程股份有限公司 重组神经元特异性烯醇化酶及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753446A (en) * 1993-04-15 1998-05-19 National Jewish Center For Immunology & Respiratory Medicine Mitogen ERK kinase kinase (MEKK) assay

Also Published As

Publication number Publication date
PL2069395T3 (pl) 2012-06-29
CA2664841A1 (en) 2008-04-03
IL218442A0 (en) 2012-04-30
NZ576409A (en) 2012-02-24
IL197868A0 (en) 2011-08-01
NO20091662L (no) 2009-06-29
AU2007301966B2 (en) 2013-02-21
DK2069395T3 (da) 2012-05-14
ES2381304T3 (es) 2012-05-25
EP2069395B1 (en) 2012-01-25
JP2010505104A (ja) 2010-02-18
EP2069395A1 (en) 2009-06-17
ATE542831T1 (de) 2012-02-15
EA200970332A1 (ru) 2009-10-30
CN101578295A (zh) 2009-11-11
BRPI0717282A2 (pt) 2013-10-15
US20100028907A1 (en) 2010-02-04
WO2008037792A1 (en) 2008-04-03
AU2007301966A1 (en) 2008-04-03
IL197868A (en) 2013-03-24
EA016731B1 (ru) 2012-07-30
CN101578295B (zh) 2013-02-27
KR20090094227A (ko) 2009-09-04
US8071721B2 (en) 2011-12-06

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