PT1981572E - Distribuição pulmonar de inibidor de alfa-i proteinase - Google Patents

Distribuição pulmonar de inibidor de alfa-i proteinase

Info

Publication number
PT1981572E
PT1981572E PT77061257T PT07706125T PT1981572E PT 1981572 E PT1981572 E PT 1981572E PT 77061257 T PT77061257 T PT 77061257T PT 07706125 T PT07706125 T PT 07706125T PT 1981572 E PT1981572 E PT 1981572E
Authority
PT
Portugal
Prior art keywords
alpha
proteinase inhibitor
pulmonary delivery
pulmonary
delivery
Prior art date
Application number
PT77061257T
Other languages
English (en)
Inventor
Shabtai Bauer
Manfred Keller
Martin Knoch
Original Assignee
Pari Pharma Gmbh
Kamada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pari Pharma Gmbh, Kamada Ltd filed Critical Pari Pharma Gmbh
Publication of PT1981572E publication Critical patent/PT1981572E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT77061257T 2006-02-09 2007-02-08 Distribuição pulmonar de inibidor de alfa-i proteinase PT1981572E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77146506P 2006-02-09 2006-02-09
US77365406P 2006-02-16 2006-02-16

Publications (1)

Publication Number Publication Date
PT1981572E true PT1981572E (pt) 2013-02-26

Family

ID=38345545

Family Applications (1)

Application Number Title Priority Date Filing Date
PT77061257T PT1981572E (pt) 2006-02-09 2007-02-08 Distribuição pulmonar de inibidor de alfa-i proteinase

Country Status (13)

Country Link
US (3) US20090304604A1 (pt)
EP (3) EP2740487B1 (pt)
AU (2) AU2007213343B2 (pt)
BR (2) BRPI0707635A2 (pt)
CA (2) CA2641872A1 (pt)
DK (1) DK1981572T3 (pt)
ES (2) ES2399449T3 (pt)
HK (1) HK1198919A1 (pt)
MX (2) MX2008010173A (pt)
PL (1) PL1981572T3 (pt)
PT (1) PT1981572E (pt)
RU (2) RU2472524C2 (pt)
WO (2) WO2007091267A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2740487B1 (en) * 2006-02-09 2018-02-28 Kamada Ltd. Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases
US8551534B2 (en) 2007-10-10 2013-10-08 Parion Sciences, Inc. Inhaled hypertonic saline delivered by a heated nasal cannula
AU2010315325B2 (en) 2009-11-03 2014-11-27 Grifols Therapeutics Inc. Composition, method, and kit for alpha-1 proteinase inhibitor
US8648177B2 (en) 2009-11-24 2014-02-11 Grifols Therapeutics Inc. Lyophilization methods, compositions, and kits
US8945605B2 (en) * 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
CA2838529C (en) 2011-06-07 2020-03-24 Parion Sciences, Inc. Methods of treatment
AU2012323992A1 (en) * 2011-12-19 2013-07-04 Lfb Usa, Inc. Recombinant human alpha-1-antitrypsin for the treatment of inflammatory disorders
CN103889436A (zh) 2011-12-30 2014-06-25 基立福有限公司 用于延迟肺部症状加重的发作或进展的α1-蛋白酶抑制剂
EP2854833A1 (en) * 2012-05-25 2015-04-08 Inserm Agents for treating cystic fibrosis
CN104470427B (zh) 2012-06-08 2017-11-21 皇家飞利浦有限公司 用于监测患者的肺功能的方法和系统
EP2956003A2 (en) 2013-02-13 2015-12-23 Laboratoire Français du Fractionnement et des Biotechnologies Proteins with modified glycosylation and methods of production thereof
WO2016087582A1 (en) * 2014-12-03 2016-06-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods and pharmaceutical compositions for the prevention and/or treatment of acute exacerbations of chronic obstructive pulmonary disease
EP3463280B1 (en) * 2016-05-31 2022-07-06 Polyphor Ag Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof
EP3348293A1 (en) 2017-01-17 2018-07-18 Carebay Europe Ltd. Medicament delivery device
WO2018154568A1 (en) * 2017-02-21 2018-08-30 Kamada Ltd. Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases
IL275328B2 (en) * 2017-12-12 2024-03-01 Kamada Ltd Methods for inducing immune tolerance and reducing antibody response against drugs
WO2020157752A1 (en) * 2019-01-29 2020-08-06 Kamada Ltd Pharmaceutical aerosol composition
EP4125804A1 (en) 2020-04-01 2023-02-08 UNION therapeutics A/S Treatment
JP2023520229A (ja) 2020-04-01 2023-05-16 ユニオン・セラピューティクス・アー／エス 製剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4697003A (en) * 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US5093316A (en) * 1986-12-24 1992-03-03 John Lezdey Treatment of inflammation
JP2656944B2 (ja) * 1987-04-30 1997-09-24 クーパー ラボラトリーズ タンパク質性治療剤のエアロゾール化
US5518179A (en) * 1991-12-04 1996-05-21 The Technology Partnership Limited Fluid droplets production apparatus and method
US5780440A (en) 1996-06-17 1998-07-14 Protease Sciences Inc. Treatment of pulmonary disease with protease inhibitors
AP1342A (en) * 1998-03-16 2004-12-15 Nektar Therapeutics Aerosolized active agent delivery.
DE19953317C1 (de) * 1999-11-05 2001-02-01 Pari Gmbh Inhalationsvernebler
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
EP1295647A1 (en) 2001-09-24 2003-03-26 The Technology Partnership Public Limited Company Nozzles in perforate membranes and their manufacture
DE60235883D1 (de) 2002-08-02 2010-05-20 Pari Pharma Gmbh Vorrichtung zur Erzeugung von Flüssigkeitströpfchen
DE10257381B4 (de) 2002-12-09 2006-09-14 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung
PT1664123E (pt) 2003-09-22 2008-07-16 Kamada Ltd Preparação em larga escala de um inibidor da alfa-1 proteinase e sua utilização
SI1684719T1 (sl) * 2003-11-14 2012-07-31 Baxter Int Sestavki alfa antitripsina in postopki zdravljenja ob uporabi takih sestavkov
EP1737499A4 (en) * 2004-03-09 2009-07-22 Arriva Pharmaceuticals Inc TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE BY INHALATION OF LOW DOSES OF A PROTEASE HEMMER
EP2740487B1 (en) * 2006-02-09 2018-02-28 Kamada Ltd. Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases

Also Published As

Publication number Publication date
WO2007091267A2 (en) 2007-08-16
RU2008135580A (ru) 2010-03-20
AU2007213343B2 (en) 2012-09-13
CA2641875A1 (en) 2007-08-16
EP2740487A1 (en) 2014-06-11
AU2007213344B2 (en) 2012-11-15
WO2007091266A3 (en) 2007-11-15
HK1198919A1 (en) 2015-06-19
RU2472524C2 (ru) 2013-01-20
EP2740487B1 (en) 2018-02-28
RU2433841C2 (ru) 2011-11-20
ES2399449T3 (es) 2013-04-01
CA2641875C (en) 2016-10-04
PL1981572T3 (pl) 2013-05-31
US20090304604A1 (en) 2009-12-10
US7973005B2 (en) 2011-07-05
US20120211005A1 (en) 2012-08-23
DK1981572T3 (da) 2013-03-04
BRPI0707634A2 (pt) 2011-05-10
WO2007091267A3 (en) 2007-11-22
AU2007213344A1 (en) 2007-08-16
US20090131305A1 (en) 2009-05-21
AU2007213343A1 (en) 2007-08-16
ES2664624T3 (es) 2018-04-20
WO2007091266A2 (en) 2007-08-16
EP1981572A2 (en) 2008-10-22
BRPI0707635A2 (pt) 2011-05-10
CA2641872A1 (en) 2007-08-16
EP1981531A2 (en) 2008-10-22
MX2008010173A (es) 2009-02-12
RU2008135582A (ru) 2010-03-20
MX2008010172A (es) 2009-09-07
EP1981572B1 (en) 2012-11-21

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