PT1819704E - Derivado amida de ácido pirrolopiridina-2-carboxílico útil como inibidor de glicogénio fosforilase - Google Patents
Derivado amida de ácido pirrolopiridina-2-carboxílico útil como inibidor de glicogénio fosforilase Download PDFInfo
- Publication number
- PT1819704E PT1819704E PT05815826T PT05815826T PT1819704E PT 1819704 E PT1819704 E PT 1819704E PT 05815826 T PT05815826 T PT 05815826T PT 05815826 T PT05815826 T PT 05815826T PT 1819704 E PT1819704 E PT 1819704E
- Authority
- PT
- Portugal
- Prior art keywords
- pyrrolopyridine
- inhibitor
- carboxylic acid
- acid amide
- glycogen phosphorylase
- Prior art date
Links
- YWHNNPXTZCBOJQ-UHFFFAOYSA-N 1h-pyrrolo[3,2-b]pyridine-2-carboxamide Chemical class C1=CC=C2NC(C(=O)N)=CC2=N1 YWHNNPXTZCBOJQ-UHFFFAOYSA-N 0.000 title abstract 2
- 102000007390 Glycogen Phosphorylase Human genes 0.000 title abstract 2
- 108010046163 Glycogen Phosphorylase Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 239000000543 intermediate Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63246304P | 2004-12-02 | 2004-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1819704E true PT1819704E (pt) | 2008-10-06 |
Family
ID=35735250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05815826T PT1819704E (pt) | 2004-12-02 | 2005-12-02 | Derivado amida de ácido pirrolopiridina-2-carboxílico útil como inibidor de glicogénio fosforilase |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8664397B2 (enExample) |
| EP (1) | EP1819704B1 (enExample) |
| JP (1) | JP2008521874A (enExample) |
| AT (1) | ATE400574T1 (enExample) |
| DE (1) | DE602005008099D1 (enExample) |
| DK (1) | DK1819704T3 (enExample) |
| ES (1) | ES2309822T3 (enExample) |
| PL (1) | PL1819704T3 (enExample) |
| PT (1) | PT1819704E (enExample) |
| WO (1) | WO2006059165A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| WO2008057930A2 (en) | 2006-11-02 | 2008-05-15 | Aestus Therapeutics, Inc. | Methods of treating neuropathic pain with retinoic acid receptor agonists |
| CN103626825B (zh) * | 2013-09-30 | 2015-10-07 | 承德医学院 | 靶向肝脏的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途 |
| CN103626826B (zh) * | 2013-09-30 | 2015-10-21 | 承德医学院 | 含偶氮键的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途 |
| CN103626837B (zh) * | 2013-09-30 | 2016-11-23 | 承德医学院 | 含生物可裂解二肽的糖原磷酸化酶抑制剂胆酸类衍生物、其制备方法及医药用途 |
| CN103819486B (zh) * | 2014-01-27 | 2016-08-17 | 承德医学院 | 标记血清糖原磷酸化酶浓度水平的光亲和标记探针分子、其制备方法及医药用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0021831D0 (en) | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| US7405210B2 (en) * | 2003-05-21 | 2008-07-29 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase |
| EP1636224B1 (en) | 2003-05-21 | 2010-07-14 | Prosidion Limited | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phoshorylase |
-
2005
- 2005-12-02 JP JP2007543935A patent/JP2008521874A/ja not_active Withdrawn
- 2005-12-02 EP EP05815826A patent/EP1819704B1/en not_active Expired - Lifetime
- 2005-12-02 US US11/792,183 patent/US8664397B2/en not_active Expired - Fee Related
- 2005-12-02 AT AT05815826T patent/ATE400574T1/de active
- 2005-12-02 PL PL05815826T patent/PL1819704T3/pl unknown
- 2005-12-02 DK DK05815826T patent/DK1819704T3/da active
- 2005-12-02 DE DE602005008099T patent/DE602005008099D1/de not_active Expired - Lifetime
- 2005-12-02 ES ES05815826T patent/ES2309822T3/es not_active Expired - Lifetime
- 2005-12-02 PT PT05815826T patent/PT1819704E/pt unknown
- 2005-12-02 WO PCT/GB2005/050234 patent/WO2006059165A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005008099D1 (de) | 2008-08-21 |
| DK1819704T3 (da) | 2008-10-20 |
| PL1819704T3 (pl) | 2008-12-31 |
| US20080293761A1 (en) | 2008-11-27 |
| HK1107984A1 (en) | 2008-04-25 |
| ATE400574T1 (de) | 2008-07-15 |
| US8664397B2 (en) | 2014-03-04 |
| JP2008521874A (ja) | 2008-06-26 |
| ES2309822T3 (es) | 2008-12-16 |
| EP1819704A1 (en) | 2007-08-22 |
| WO2006059165A1 (en) | 2006-06-08 |
| EP1819704B1 (en) | 2008-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009003834A (es) | Derivados de pirrolidina como inhibidores de iap. | |
| TW200833326A (en) | Chemical compounds 572 | |
| MX2008012490A (es) | Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa-iv para el tratamiento o prevencion de diabetes. | |
| TW200628463A (en) | Heteroaryl compounds | |
| MY150787A (en) | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of prevention of diabetes | |
| TW200728305A (en) | Spiropiperidine beta-sectetase inhibitors for the treatment of alzheimer's disease | |
| UA83875C2 (ru) | Производные хинолина для применения в качестве микобактериальных ингибиторов | |
| MX2007011023A (es) | 2-(4-oxo-4h-quinazolin-3-il) acetamidas y su uso como antagonistas de vasopresin v3. | |
| CY1111327T1 (el) | Υποκατεστημενα παραγωγα κυκλοεξυλοξεικου οξεος | |
| MX2008010884A (es) | Acidos 4-fenil-tiazol-5-carboxilicos y amidas de acidos 4-fenil-tiazol-5-carboxilicos como inhibidores de la plk1. | |
| WO2006047415A3 (en) | FACTOR Xa COMPOUNDS | |
| MXPA05010020A (es) | Derivados de oxamida. | |
| EP1794120A4 (en) | peptidase | |
| MXPA06000936A (es) | Derivados de nicotinamida utiles como inhibidores de pde4. | |
| TW200633977A (en) | Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives | |
| TW200628153A (en) | Novel compounds | |
| PL1819704T3 (pl) | Amidowe pochodne kwasu pirolopirydyno-2-karboksylowego użyteczne jako inhibitory fosforylazy glikogenowej | |
| GB0407025D0 (en) | Novel compounds | |
| TNSN06260A1 (en) | Process for the preparation of tryptase inhibitors | |
| SI1745010T1 (sl) | Substituirani cikloheksil-1,4-diaminski derivati | |
| WO2006031929A3 (en) | Thiazolopyridine kinase inhibitors | |
| TW200621703A (en) | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | |
| MX2007007446A (es) | Procesos para la produccion de 4-aminoquinazolinas. | |
| TW200719889A (en) | Amino acid derivatives | |
| TW200745133A (en) | New compounds II |