PT1789403E - Derivados de n-(fenil-oxazol-4-ilmetoximetil)-ciclo-hexilsuccinamida e compostos relacionados como ligandos dos ppar (receptores activados de proliferadores de peroxisomas) para o tratamento da hiperlipidemia e diabetes - Google Patents
Derivados de n-(fenil-oxazol-4-ilmetoximetil)-ciclo-hexilsuccinamida e compostos relacionados como ligandos dos ppar (receptores activados de proliferadores de peroxisomas) para o tratamento da hiperlipidemia e diabetes Download PDFInfo
- Publication number
- PT1789403E PT1789403E PT05773889T PT05773889T PT1789403E PT 1789403 E PT1789403 E PT 1789403E PT 05773889 T PT05773889 T PT 05773889T PT 05773889 T PT05773889 T PT 05773889T PT 1789403 E PT1789403 E PT 1789403E
- Authority
- PT
- Portugal
- Prior art keywords
- hyperlipidaemie
- ylmethoxymethyl
- ppar
- oxazol
- ligands
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004039509A DE102004039509B4 (de) | 2004-08-14 | 2004-08-14 | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1789403E true PT1789403E (pt) | 2009-05-19 |
Family
ID=35385508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05773889T PT1789403E (pt) | 2004-08-14 | 2005-07-30 | Derivados de n-(fenil-oxazol-4-ilmetoximetil)-ciclo-hexilsuccinamida e compostos relacionados como ligandos dos ppar (receptores activados de proliferadores de peroxisomas) para o tratamento da hiperlipidemia e diabetes |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7598281B2 (pt) |
| EP (1) | EP1789403B1 (pt) |
| JP (1) | JP2008509892A (pt) |
| KR (1) | KR20070040812A (pt) |
| CN (1) | CN101006066A (pt) |
| AR (1) | AR053526A1 (pt) |
| AT (1) | ATE426596T1 (pt) |
| AU (1) | AU2005274493A1 (pt) |
| BR (1) | BRPI0514359A (pt) |
| CA (1) | CA2576554A1 (pt) |
| DE (2) | DE102004039509B4 (pt) |
| DK (1) | DK1789403T3 (pt) |
| ES (1) | ES2324675T3 (pt) |
| IL (1) | IL181009A0 (pt) |
| MX (1) | MX2007000614A (pt) |
| PE (1) | PE20060640A1 (pt) |
| PT (1) | PT1789403E (pt) |
| TW (1) | TW200621732A (pt) |
| UY (1) | UY29065A1 (pt) |
| WO (1) | WO2006018116A1 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6113562A (en) | 1998-06-01 | 2000-09-05 | Peter M. Bonutti | Shoulder orthosis |
| US6502577B1 (en) | 2000-09-18 | 2003-01-07 | Peter M. Bonutti | Method for moving finger joints |
| US6503213B2 (en) | 2000-12-01 | 2003-01-07 | Peter M. Bonutti | Method of using a neck brace |
| US6575926B2 (en) | 2000-12-15 | 2003-06-10 | Bonutti 2003 Trust-A | Myofascial strap |
| US8066656B2 (en) | 2005-10-28 | 2011-11-29 | Bonutti Research, Inc. | Range of motion device |
| US7452342B2 (en) | 2004-03-08 | 2008-11-18 | Bonutti Research Inc. | Range of motion device |
| US8012108B2 (en) | 2005-08-12 | 2011-09-06 | Bonutti Research, Inc. | Range of motion system and method |
| CN101272784A (zh) | 2005-09-29 | 2008-09-24 | 塞诺菲-安万特股份有限公司 | 苯基-和吡啶基-1,2,4-噁二唑酮衍生物、它们的制备方法和它们作为药物的用途 |
| CA2677333A1 (en) | 2007-02-05 | 2008-08-14 | Bonutti Research Inc. | Knee orthosis |
| WO2009015364A1 (en) | 2007-07-25 | 2009-01-29 | Bonutti Research Inc. | Orthosis apparatus and method of using an orthosis apparatus |
| US8905950B2 (en) | 2008-03-04 | 2014-12-09 | Bonutti Research, Inc. | Shoulder ROM orthosis |
| EP2486923B1 (en) * | 2011-02-11 | 2015-09-09 | Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG | Histone deacetylase (HDAC) inhibiting compounds and method of making same |
| US9402759B2 (en) | 2013-02-05 | 2016-08-02 | Bonutti Research, Inc. | Cervical traction systems and method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000064876A1 (en) * | 1999-04-28 | 2000-11-02 | Aventis Pharma Deutschland Gmbh | Tri-aryl acid derivatives as ppar receptor ligands |
| JP4316787B2 (ja) * | 2000-01-11 | 2009-08-19 | 壽製薬株式会社 | エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 |
| CA2458210C (en) * | 2001-08-31 | 2011-09-20 | Aventis Pharma Deutschland Gmbh | Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar-activators |
| DE10308355A1 (de) * | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
-
2004
- 2004-08-14 DE DE102004039509A patent/DE102004039509B4/de not_active Expired - Fee Related
-
2005
- 2005-07-30 ES ES05773889T patent/ES2324675T3/es active Active
- 2005-07-30 WO PCT/EP2005/008282 patent/WO2006018116A1/de active Application Filing
- 2005-07-30 MX MX2007000614A patent/MX2007000614A/es active IP Right Grant
- 2005-07-30 CN CNA2005800276576A patent/CN101006066A/zh active Pending
- 2005-07-30 EP EP05773889A patent/EP1789403B1/de not_active Not-in-force
- 2005-07-30 JP JP2007525216A patent/JP2008509892A/ja not_active Abandoned
- 2005-07-30 KR KR1020077003480A patent/KR20070040812A/ko not_active Application Discontinuation
- 2005-07-30 AT AT05773889T patent/ATE426596T1/de not_active IP Right Cessation
- 2005-07-30 AU AU2005274493A patent/AU2005274493A1/en not_active Abandoned
- 2005-07-30 BR BRPI0514359-4A patent/BRPI0514359A/pt not_active IP Right Cessation
- 2005-07-30 DE DE502005006955T patent/DE502005006955D1/de active Active
- 2005-07-30 DK DK05773889T patent/DK1789403T3/da active
- 2005-07-30 PT PT05773889T patent/PT1789403E/pt unknown
- 2005-07-30 CA CA002576554A patent/CA2576554A1/en not_active Abandoned
- 2005-08-05 PE PE2005000910A patent/PE20060640A1/es not_active Application Discontinuation
- 2005-08-11 AR ARP050103352A patent/AR053526A1/es not_active Application Discontinuation
- 2005-08-11 TW TW094127240A patent/TW200621732A/zh unknown
- 2005-08-12 UY UY29065A patent/UY29065A1/es unknown
-
2007
- 2007-01-28 IL IL181009A patent/IL181009A0/en unknown
- 2007-02-07 US US11/672,302 patent/US7598281B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1789403T3 (da) | 2009-07-06 |
| US20070197605A1 (en) | 2007-08-23 |
| CN101006066A (zh) | 2007-07-25 |
| KR20070040812A (ko) | 2007-04-17 |
| EP1789403A1 (de) | 2007-05-30 |
| EP1789403B1 (de) | 2009-03-25 |
| IL181009A0 (en) | 2007-07-04 |
| DE102004039509B4 (de) | 2006-09-21 |
| CA2576554A1 (en) | 2006-02-23 |
| ATE426596T1 (de) | 2009-04-15 |
| BRPI0514359A (pt) | 2008-06-10 |
| US7598281B2 (en) | 2009-10-06 |
| JP2008509892A (ja) | 2008-04-03 |
| AR053526A1 (es) | 2007-05-09 |
| PE20060640A1 (es) | 2006-07-27 |
| TW200621732A (en) | 2006-07-01 |
| DE102004039509A1 (de) | 2006-03-23 |
| WO2006018116A1 (de) | 2006-02-23 |
| ES2324675T3 (es) | 2009-08-12 |
| DE502005006955D1 (de) | 2009-05-07 |
| UY29065A1 (es) | 2006-02-24 |
| AU2005274493A1 (en) | 2006-02-23 |
| MX2007000614A (es) | 2007-03-30 |
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