PT1720538E - Método para indução de morte celular com sequestrantes de carbonilo - Google Patents
Método para indução de morte celular com sequestrantes de carbonilo Download PDFInfo
- Publication number
- PT1720538E PT1720538E PT05723942T PT05723942T PT1720538E PT 1720538 E PT1720538 E PT 1720538E PT 05723942 T PT05723942 T PT 05723942T PT 05723942 T PT05723942 T PT 05723942T PT 1720538 E PT1720538 E PT 1720538E
- Authority
- PT
- Portugal
- Prior art keywords
- cell death
- inducing cell
- cells
- carbonyl
- carbonyl scavengers
- Prior art date
Links
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 title abstract 3
- 230000030833 cell death Effects 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 230000001133 acceleration Effects 0.000 abstract 1
- 230000005775 apoptotic pathway Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000034994 death Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Storage Of Fruits Or Vegetables (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54980504P | 2004-03-02 | 2004-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1720538E true PT1720538E (pt) | 2008-12-26 |
Family
ID=34919540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05723942T PT1720538E (pt) | 2004-03-02 | 2005-03-01 | Método para indução de morte celular com sequestrantes de carbonilo |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7217739B2 (pt) |
| EP (1) | EP1720538B1 (pt) |
| JP (1) | JP4642837B2 (pt) |
| CN (1) | CN100522153C (pt) |
| AT (1) | ATE413871T1 (pt) |
| AU (1) | AU2005219390B2 (pt) |
| CA (1) | CA2557666C (pt) |
| DE (1) | DE602005010980D1 (pt) |
| DK (1) | DK1720538T3 (pt) |
| ES (1) | ES2317214T3 (pt) |
| HK (1) | HK1102768A1 (pt) |
| HR (1) | HRP20080599T3 (pt) |
| PL (1) | PL1720538T3 (pt) |
| PT (1) | PT1720538E (pt) |
| RS (1) | RS50632B (pt) |
| SI (1) | SI1720538T1 (pt) |
| WO (1) | WO2005084659A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8754045B2 (en) * | 2006-05-12 | 2014-06-17 | James A. Livingston | Enzymatic debridement therapy for abnormal cell proliferation |
| RU2447848C2 (ru) * | 2010-07-26 | 2012-04-20 | Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" | Способ профилактики полостных спаек |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4762705A (en) * | 1981-11-10 | 1988-08-09 | Adolf W. Schwimmer | Cancer therapy with interferon |
| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| US6093745A (en) * | 1997-11-25 | 2000-07-25 | Psorx, L.L.C. | Methods and composition for treating skin proliferative diseases |
| US6811788B2 (en) * | 2000-01-19 | 2004-11-02 | Baofa Yu | Combinations and methods for treating neoplasms |
| DE60129008T2 (de) * | 2000-04-14 | 2007-10-11 | Niadyne Corp., Tucson | Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten |
| US6417235B2 (en) * | 2000-04-14 | 2002-07-09 | University Of Kentucky Research Foundation | Method and use of α-amino-β-mercapto-ethane derivatives as dicarbonyl scavengers for treatment of conditions resulting from protein, lipid, and DNA damage |
| US6723168B2 (en) * | 2001-06-20 | 2004-04-20 | Taiwan Semiconductor Manufacturing Co., Ltd. | Spin-coater with self-cleaning cup and method of using |
| WO2003004469A1 (en) * | 2001-07-02 | 2003-01-16 | Dabur Research Foundation | Anticancer activity of imino acid conjugates of methylglyoxal |
| US7071164B2 (en) * | 2001-08-16 | 2006-07-04 | Kimberly-Clark Worldwide, Inc. | Anti-cancer and wound healing compounds |
-
2005
- 2005-03-01 ES ES05723942T patent/ES2317214T3/es active Active
- 2005-03-01 DE DE602005010980T patent/DE602005010980D1/de active Active
- 2005-03-01 PT PT05723942T patent/PT1720538E/pt unknown
- 2005-03-01 AU AU2005219390A patent/AU2005219390B2/en not_active Ceased
- 2005-03-01 PL PL05723942T patent/PL1720538T3/pl unknown
- 2005-03-01 AT AT05723942T patent/ATE413871T1/de active
- 2005-03-01 WO PCT/US2005/006288 patent/WO2005084659A1/en active Application Filing
- 2005-03-01 CN CNB2005800065503A patent/CN100522153C/zh not_active Expired - Fee Related
- 2005-03-01 JP JP2007501872A patent/JP4642837B2/ja not_active Expired - Fee Related
- 2005-03-01 DK DK05723942T patent/DK1720538T3/da active
- 2005-03-01 RS RSP-2008/0557A patent/RS50632B/sr unknown
- 2005-03-01 EP EP05723942A patent/EP1720538B1/en active Active
- 2005-03-01 CA CA2557666A patent/CA2557666C/en not_active Expired - Fee Related
- 2005-03-01 US US11/069,292 patent/US7217739B2/en active Active
- 2005-03-01 SI SI200530571T patent/SI1720538T1/sl unknown
-
2007
- 2007-10-16 HK HK07111130A patent/HK1102768A1/xx not_active IP Right Cessation
-
2008
- 2008-12-17 HR HR20080599T patent/HRP20080599T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1720538A4 (en) | 2007-04-11 |
| PL1720538T3 (pl) | 2009-04-30 |
| EP1720538B1 (en) | 2008-11-12 |
| SI1720538T1 (sl) | 2009-04-30 |
| JP2007526313A (ja) | 2007-09-13 |
| AU2005219390B2 (en) | 2008-05-01 |
| CA2557666C (en) | 2010-04-27 |
| DK1720538T3 (da) | 2009-01-19 |
| RS50632B (sr) | 2010-06-30 |
| CN1964710A (zh) | 2007-05-16 |
| HRP20080599T3 (en) | 2009-01-31 |
| ES2317214T3 (es) | 2009-04-16 |
| HK1102768A1 (en) | 2007-12-07 |
| AU2005219390A1 (en) | 2005-09-15 |
| CA2557666A1 (en) | 2005-09-15 |
| CN100522153C (zh) | 2009-08-05 |
| US20050197400A1 (en) | 2005-09-08 |
| JP4642837B2 (ja) | 2011-03-02 |
| ATE413871T1 (de) | 2008-11-15 |
| US7217739B2 (en) | 2007-05-15 |
| DE602005010980D1 (de) | 2008-12-24 |
| WO2005084659A1 (en) | 2005-09-15 |
| EP1720538A1 (en) | 2006-11-15 |
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