PT1502599E - Terapia anti-angiogénica activa - Google Patents
Terapia anti-angiogénica activa Download PDFInfo
- Publication number
- PT1502599E PT1502599E PT03711811T PT03711811T PT1502599E PT 1502599 E PT1502599 E PT 1502599E PT 03711811 T PT03711811 T PT 03711811T PT 03711811 T PT03711811 T PT 03711811T PT 1502599 E PT1502599 E PT 1502599E
- Authority
- PT
- Portugal
- Prior art keywords
- antiangiogenic therapy
- mutated vegf
- vegf
- mutated
- antiangiogenic
- Prior art date
Links
- 101100372758 Danio rerio vegfaa gene Proteins 0.000 title 1
- 101150030763 Vegfa gene Proteins 0.000 title 1
- 238000011122 anti-angiogenic therapy Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
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- A61K2039/53—DNA (RNA) vaccination
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Vascular Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20020076A CU23178A1 (es) | 2002-04-15 | 2002-04-15 | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1502599E true PT1502599E (pt) | 2011-08-03 |
Family
ID=40134850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT03711811T PT1502599E (pt) | 2002-04-15 | 2003-04-11 | Terapia anti-angiogénica activa |
Country Status (17)
Country | Link |
---|---|
US (3) | US7556809B2 (pt) |
EP (1) | EP1502599B1 (pt) |
JP (1) | JP4741800B2 (pt) |
KR (1) | KR100704127B1 (pt) |
CN (1) | CN1646153B (pt) |
AR (1) | AR039285A1 (pt) |
AT (1) | ATE511851T1 (pt) |
AU (1) | AU2003218603B2 (pt) |
CA (1) | CA2480079C (pt) |
CU (1) | CU23178A1 (pt) |
DK (1) | DK1502599T3 (pt) |
ES (1) | ES2365329T3 (pt) |
PT (1) | PT1502599E (pt) |
RU (1) | RU2329824C2 (pt) |
SI (1) | SI1502599T1 (pt) |
WO (1) | WO2003086450A1 (pt) |
ZA (1) | ZA200408460B (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU23178A1 (es) * | 2002-04-15 | 2006-09-22 | Ct Ingenieria Genetica Biotech | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
EP2270042B1 (en) * | 2002-09-12 | 2015-01-14 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
WO2006031689A2 (en) * | 2004-09-13 | 2006-03-23 | Genzyme Corporation | Multimeric constructs |
ES2442294T3 (es) * | 2005-02-28 | 2014-02-11 | Oncotherapy Science, Inc. | Péptidos epítopos derivados del receptor 1 del factor de crecimiento endotelial vascular y vacunas que contienen estos péptidos |
US20060234941A1 (en) * | 2005-04-15 | 2006-10-19 | The Gov. Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Peptide epitopes of VEGFR-2/KDR that inhibit angiogenesis |
ES2350269T3 (es) * | 2006-01-18 | 2011-01-20 | The General Hospital Corporation | Métodos de aumento de la función linfática. |
CN101394857A (zh) * | 2006-02-01 | 2009-03-25 | 爱吉恩公司 | 含有寡聚核苷酸和无毒lps的用于治疗癌症的组合物 |
CN103784938A (zh) | 2007-02-16 | 2014-05-14 | 肿瘤疗法科学股份有限公司 | 脉络膜血管新生的疫苗疗法 |
RU2488592C2 (ru) * | 2007-08-08 | 2013-07-27 | Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем | Пептиды направленного действия на vegfr-1/nrp-1 |
TWI436775B (zh) * | 2007-08-24 | 2014-05-11 | Oncotherapy Science Inc | 以抗原胜肽合併化療藥劑治療胰臟癌 |
AU2009240461A1 (en) * | 2008-04-24 | 2009-10-29 | 3M Innovative Properties Company | Analysis of nucleic acid amplification curves using wavelet transformation |
WO2010058426A2 (en) * | 2008-11-21 | 2010-05-27 | Reliance Life Sciences Pvt. Ltd. | Inhibition of vegf-a secretion, angiogenesis and/or neoangiogenesis by sina mediated knockdown of vegf-c and rhoa |
DK2403935T3 (en) | 2009-03-04 | 2017-09-11 | Univ Pennsylvania | COMPOSITIONS CONTAINING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF |
TW201109029A (en) * | 2009-06-11 | 2011-03-16 | Oncotherapy Science Inc | Vaccine therapy for choroidal neovascularization |
PT2601214T (pt) | 2010-08-06 | 2017-12-20 | Genzyme Corp | Composições de antagonistas de vegf e utilizações destes |
RU2444378C1 (ru) * | 2010-09-06 | 2012-03-10 | Олег Германович Макеев | Способ лечения коронарной недостаточности при моделируемой ишемии миокарда |
WO2012088563A1 (en) * | 2010-11-24 | 2012-07-05 | Vegenics Pty Limited | Vegfr-2-specific forms of vegf-d and vegf-c and uses thereof |
WO2013074820A1 (en) | 2011-11-16 | 2013-05-23 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Immunogenic tumor associated stromal cell antigen peptides and methods of their use |
US10543261B2 (en) * | 2012-08-31 | 2020-01-28 | Osaka University | DNA vaccine containing VEGF-specific epitope and/or angiopoietin-2-specific epitope |
EP3096769A1 (en) * | 2014-01-21 | 2016-11-30 | University of Helsinki | Therapeutic use of vegfr-3 ligands |
KR101509047B1 (ko) * | 2014-07-28 | 2015-04-08 | 한국생명공학연구원 | Neuropilin 1 유전자를 이용한 천식 진단 및 천식 치료제 스크리닝 방법 |
JP2019501663A (ja) | 2016-01-15 | 2019-01-24 | ユニバーシティー オブ メリーランド,カレッジ パーク | グリコシンターゼとしてのEndo−S2変異体、糖タンパク質の製造方法および糖タンパク質の糖鎖操作のための使用 |
AU2016413999B2 (en) * | 2016-07-05 | 2020-05-14 | Ibentrus, Inc. | Cancer treatment composition for inhibiting tumor angiogenesis, containing VEGF deep blocker, and preparation method therefor |
EP3497229A1 (en) | 2016-08-10 | 2019-06-19 | University of Maryland, College Park | Designer alpha 1,6-fucosidase mutants enable direct core fucosylation of intact n-glycopeptides and n-glycoproteins |
CN110612115A (zh) * | 2017-05-19 | 2019-12-24 | 学校法人庆应义塾 | 针对脑神经疾病的肽疫苗和肽疫苗组合物 |
US10836815B2 (en) | 2017-06-29 | 2020-11-17 | University Of Maryland, College Park | Generation and comparative kinetic analysis of new glycosynthase mutants from Streptococcus pyogenes endoglycosidases for antibody glycoengineering |
CN111487398B (zh) * | 2019-01-25 | 2022-11-11 | 四川大学华西医院 | 血管瘤治疗的生物标记物 |
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US5219739A (en) * | 1989-07-27 | 1993-06-15 | Scios Nova Inc. | DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121 |
CA2158745C (en) * | 1993-03-25 | 2007-06-19 | Richard L. Kendall | Inhibitor of vascular endothelial cell growth factor |
US6149921A (en) * | 1993-12-29 | 2000-11-21 | Centro De Inmunologia Molecular | Vaccine compositions for eliciting an immune response against N-acetylated gangliosides and their use for cancer treatment |
AU3374795A (en) * | 1994-08-29 | 1996-03-22 | Prizm Pharmaceuticals, Inc. | Conjugates of vascular endothelial growth factor with targeted agents |
EP1032583A4 (en) * | 1998-03-06 | 2005-02-02 | Imclone Systems Inc | Active immunization against angiotens |
JP2002514573A (ja) * | 1998-05-08 | 2002-05-21 | スローン − ケッタリング インスティチュート フォー キャンサー リサーチ | 能動的なワクチン接種のための組成物および方法 |
AU776473C (en) | 1999-03-11 | 2005-04-14 | Entremed, Inc | Compositions and methods for treating cancer and hyperproliferative disorders |
JP2003528824A (ja) * | 2000-02-04 | 2003-09-30 | スプラテック ファーマ インコーポレイティド | 血管内皮成長因子受容体のためのリガンド |
US7094410B2 (en) * | 2002-03-02 | 2006-08-22 | The Scripps Research Institute | DNA vaccine against proliferating endothelial cells and methods of use thereof |
CU23178A1 (es) * | 2002-04-15 | 2006-09-22 | Ct Ingenieria Genetica Biotech | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
-
2002
- 2002-04-15 CU CU20020076A patent/CU23178A1/es unknown
-
2003
- 2003-04-10 AR ARP030101264A patent/AR039285A1/es unknown
- 2003-04-11 RU RU2004133338/15A patent/RU2329824C2/ru active IP Right Revival
- 2003-04-11 SI SI200332037T patent/SI1502599T1/sl unknown
- 2003-04-11 ES ES03711811T patent/ES2365329T3/es not_active Expired - Lifetime
- 2003-04-11 AU AU2003218603A patent/AU2003218603B2/en not_active Ceased
- 2003-04-11 KR KR1020047016584A patent/KR100704127B1/ko active IP Right Grant
- 2003-04-11 DK DK03711811.4T patent/DK1502599T3/da active
- 2003-04-11 CN CN03808567.4A patent/CN1646153B/zh not_active Expired - Lifetime
- 2003-04-11 WO PCT/CU2003/000004 patent/WO2003086450A1/es active Application Filing
- 2003-04-11 JP JP2003583468A patent/JP4741800B2/ja not_active Expired - Fee Related
- 2003-04-11 US US10/511,384 patent/US7556809B2/en not_active Expired - Lifetime
- 2003-04-11 AT AT03711811T patent/ATE511851T1/de active
- 2003-04-11 CA CA2480079A patent/CA2480079C/en not_active Expired - Lifetime
- 2003-04-11 PT PT03711811T patent/PT1502599E/pt unknown
- 2003-04-11 EP EP03711811A patent/EP1502599B1/en not_active Expired - Lifetime
-
2004
- 2004-10-19 ZA ZA200408460A patent/ZA200408460B/xx unknown
-
2007
- 2007-04-17 US US11/787,522 patent/US20080254050A1/en not_active Abandoned
-
2009
- 2009-11-04 US US12/612,455 patent/US8883724B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2480079C (en) | 2013-07-30 |
RU2329824C2 (ru) | 2008-07-27 |
AU2003218603A1 (en) | 2003-10-27 |
SI1502599T1 (sl) | 2011-10-28 |
US20080254050A1 (en) | 2008-10-16 |
AU2003218603B2 (en) | 2009-05-28 |
US8883724B2 (en) | 2014-11-11 |
KR100704127B1 (ko) | 2007-04-05 |
DK1502599T3 (da) | 2011-08-01 |
JP2006501145A (ja) | 2006-01-12 |
WO2003086450A1 (es) | 2003-10-23 |
EP1502599A1 (en) | 2005-02-02 |
RU2004133338A (ru) | 2005-06-10 |
CU23178A1 (es) | 2006-09-22 |
EP1502599B1 (en) | 2011-06-08 |
US20100047265A1 (en) | 2010-02-25 |
CN1646153A (zh) | 2005-07-27 |
US20050175624A1 (en) | 2005-08-11 |
US7556809B2 (en) | 2009-07-07 |
CA2480079A1 (en) | 2003-10-23 |
JP4741800B2 (ja) | 2011-08-10 |
ZA200408460B (en) | 2005-08-30 |
CN1646153B (zh) | 2017-05-24 |
ATE511851T1 (de) | 2011-06-15 |
ES2365329T3 (es) | 2011-09-29 |
KR20040111526A (ko) | 2004-12-31 |
AR039285A1 (es) | 2005-02-16 |
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