PT1403278E - Processo de sintese da n-((s)-1-carbetoxibutil)-(s)-alanina e aplicacao a sintese do perindopril - Google Patents
Processo de sintese da n-((s)-1-carbetoxibutil)-(s)-alanina e aplicacao a sintese do perindoprilInfo
- Publication number
- PT1403278E PT1403278E PT03292404T PT03292404T PT1403278E PT 1403278 E PT1403278 E PT 1403278E PT 03292404 T PT03292404 T PT 03292404T PT 03292404 T PT03292404 T PT 03292404T PT 1403278 E PT1403278 E PT 1403278E
- Authority
- PT
- Portugal
- Prior art keywords
- synthesis
- carbethoxibutil
- application
- perindopril
- alanine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/06—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
- C07C251/08—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton being acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03292404A EP1403278B1 (fr) | 2003-09-30 | 2003-09-30 | Procédé de synthèse de la N-((S)-1-carbéthoxybutyl)-(S)-alanine et application à la synthèse du perindopril |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1403278E true PT1403278E (pt) | 2005-09-30 |
Family
ID=31970535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03292404T PT1403278E (pt) | 2003-09-30 | 2003-09-30 | Processo de sintese da n-((s)-1-carbetoxibutil)-(s)-alanina e aplicacao a sintese do perindopril |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1403278B1 (pt) |
| AR (1) | AR045849A1 (pt) |
| AT (1) | ATE297407T1 (pt) |
| DE (1) | DE60300806T2 (pt) |
| DK (1) | DK1403278T3 (pt) |
| ES (1) | ES2240926T3 (pt) |
| MY (1) | MY137391A (pt) |
| PT (1) | PT1403278E (pt) |
| SI (1) | SI1403278T1 (pt) |
| WO (1) | WO2005033127A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI21800A (sl) | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2807037B1 (fr) * | 2000-03-31 | 2002-05-10 | Adir | NOUVEAU PROCEDE DE SYNTHESE DES ESTERS DE LA N-[(s)-1- CARBOXYBUTYL]-(S)-ALANINE ET APPLICATION A LA SYNTHESE DU PERINDOPRIL |
| FR2807430B1 (fr) * | 2000-04-11 | 2002-05-17 | Adir | Nouveau procede de synthese des esters de la n-[(s)-1- carboxybutyl]-(s)-alanine et application a la synthese du perindopril |
-
2003
- 2003-09-30 PT PT03292404T patent/PT1403278E/pt unknown
- 2003-09-30 SI SI200330047T patent/SI1403278T1/xx unknown
- 2003-09-30 AT AT03292404T patent/ATE297407T1/de active
- 2003-09-30 EP EP03292404A patent/EP1403278B1/fr not_active Expired - Lifetime
- 2003-09-30 ES ES03292404T patent/ES2240926T3/es not_active Expired - Lifetime
- 2003-09-30 DK DK03292404T patent/DK1403278T3/da active
- 2003-09-30 DE DE60300806T patent/DE60300806T2/de not_active Expired - Lifetime
-
2004
- 2004-09-29 MY MYPI20043999A patent/MY137391A/en unknown
- 2004-09-29 WO PCT/FR2004/002463 patent/WO2005033127A1/fr active Application Filing
- 2004-09-29 AR ARP040103525A patent/AR045849A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2240926T3 (es) | 2005-10-16 |
| ATE297407T1 (de) | 2005-06-15 |
| DK1403278T3 (da) | 2005-10-03 |
| MY137391A (en) | 2009-01-30 |
| DE60300806T2 (de) | 2006-03-23 |
| AR045849A1 (es) | 2005-11-16 |
| EP1403278A1 (fr) | 2004-03-31 |
| WO2005033127A1 (fr) | 2005-04-14 |
| SI1403278T1 (en) | 2005-10-31 |
| DE60300806D1 (de) | 2005-07-14 |
| EP1403278B1 (fr) | 2005-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004032276D1 (de) | Tetrahydro-Naphthalen und Harnstoffderivate | |
| DE60336399D1 (de) | Chirurgisches nähinstrument | |
| BRPI0311516A2 (pt) | xampu de condicionamento que contém amino silicone | |
| DE60207663D1 (de) | Bürstendichtung und Bürstendichtungsanordnung | |
| DE60320629D1 (de) | Chirurgisches Instrument | |
| DE602004017351D1 (de) | Fft-architektur und -verfahren | |
| DE60317735D1 (de) | Authentifizierung eines elektronischen Etiketts | |
| NO20043907L (no) | Partielle og fullstendige agonister av A1-adenosinreseptorer | |
| DE60224452D1 (de) | Haarfärbeverfahren und haarfärbesatz | |
| DE60332702D1 (de) | Strahltriebwerk und Dichtung | |
| DE60323122D1 (de) | Umhüllte samen und verfahren zur umhüllung von samen | |
| EE200200586A (et) | Meetod N-[(S)-1-karboksübutüül]-(S)-alaniini estrite sünteesimiseks ja nende kasutamine perindopriili sünteesis | |
| PT1403278E (pt) | Processo de sintese da n-((s)-1-carbetoxibutil)-(s)-alanina e aplicacao a sintese do perindopril | |
| NO20024616L (no) | Ny fremgangsmåte ved syntese av N-[(S)-1-karboksybutyl]-(S)- alaninestere og anvendelse i syntese av perindopril | |
| AU2001248433A1 (en) | Novel method for synthesis of N-((S)-1-carboxybutyl)-(S)-alanine esters and use in synthesis of perindopril | |
| DE60309255D1 (de) | Abbildung und Entnahme von Gel | |
| ITMI20030178A1 (it) | Apparecchiatura e procedimento di fissaggio/ritenuta | |
| HK1118285A1 (en) | Intermediate for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril | |
| DK1400531T3 (da) | Fremgangsmåde til fremstilling af N-[(S)-1-ethoxycarbonyl-butyl]-(S)-alanin og anvendelse heraf ved syntese af perindopril | |
| DE602004030633D1 (de) | Reinigung von Amidderivaten | |
| UA7864S (uk) | Обкладинка довідково-інформаційного рекламного каталога | |
| FR2836296B1 (fr) | Source laser multilongueur d'onde | |
| UA6800S (uk) | Комплект етикеток | |
| UA6561S (uk) | Комплект етикеток | |
| UA6801S (uk) | Комплект етикеток |