PT1382346E - Meio condicionado e produto biológico difusível produzido por incubaçâo de células aprisionadas - Google Patents

Meio condicionado e produto biológico difusível produzido por incubaçâo de células aprisionadas Download PDF

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Publication number
PT1382346E
PT1382346E PT03018701T PT03018701T PT1382346E PT 1382346 E PT1382346 E PT 1382346E PT 03018701 T PT03018701 T PT 03018701T PT 03018701 T PT03018701 T PT 03018701T PT 1382346 E PT1382346 E PT 1382346E
Authority
PT
Portugal
Prior art keywords
incubating
product produced
conditioned medium
biological product
entrapped cells
Prior art date
Application number
PT03018701T
Other languages
English (en)
Inventor
Shirin Asina
Kanti Jain
Albert Rubin
Barry Smith
Kurt Stenzal
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rogosin Inst filed Critical Rogosin Inst
Publication of PT1382346E publication Critical patent/PT1382346E/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126Immunoprotecting barriers, e.g. jackets, diffusion chambers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PT03018701T 1996-04-03 1997-03-21 Meio condicionado e produto biológico difusível produzido por incubaçâo de células aprisionadas PT1382346E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62559596A 1996-04-03 1996-04-03
US08/745,063 US5888497A (en) 1996-04-03 1996-11-07 Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation

Publications (1)

Publication Number Publication Date
PT1382346E true PT1382346E (pt) 2008-01-03

Family

ID=24506799

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03018701T PT1382346E (pt) 1996-04-03 1997-03-21 Meio condicionado e produto biológico difusível produzido por incubaçâo de células aprisionadas

Country Status (4)

Country Link
US (1) US5888497A (pt)
CN (1) CN1769430A (pt)
IL (1) IL126442A (pt)
PT (1) PT1382346E (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39542E1 (en) * 1994-01-13 2007-04-03 The Rogosin Institute Preparation of agarose coated, solid agarose-collagen beads containing secretory cells
ES2260568T3 (es) * 1994-01-13 2006-11-01 The Rogosin Institute Celulas secretoras macroencapsuladas.
US7297331B2 (en) * 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
US6303151B1 (en) * 1996-04-03 2001-10-16 The Rogosin Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
AU8577498A (en) * 1997-07-22 1999-02-16 General Hospital Corporation, The Modulation of multicellular aggregates by solid stress
US20030060695A1 (en) * 2001-03-07 2003-03-27 Connelly Patrick R. Implantable artificial organ devices
US7247297B2 (en) * 2001-09-14 2007-07-24 The University Of Chicago Use of DF3/MUC1 regulated expression in gene therapy
US7262269B2 (en) * 2001-10-26 2007-08-28 The Regents Of University Of California Method for screening combinational bead library; ligands for cancer cells
US6670142B2 (en) 2001-10-26 2003-12-30 The Regents Of The University Of California Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells
US20050053586A1 (en) 2003-09-04 2005-03-10 Bryan Conn Entrapped stem cells and uses thereof
JP2007517042A (ja) 2003-12-30 2007-06-28 デュレクト コーポレーション 活性物質、好ましくはgnrhの制御放出のための、好ましくはpegおよびplgの混合物を含有するポリマーインプラント
US20060121077A1 (en) * 2004-11-11 2006-06-08 Lawrence Gazda Method for treating patients with implants of islets which have been kept in long term, in vitro culture
SG131015A1 (en) * 2005-09-15 2007-04-26 Millipore Corp Method and apparatus for making porous agarose beads
SG131016A1 (en) 2005-09-19 2007-04-26 Millipore Corp Asymmetric porous adsorptive bead
CN101272690B (zh) * 2005-09-26 2012-08-29 罗格森研究所 包含思科姆金琼脂糖的含有分泌细胞的大珠及其用途
WO2009085850A2 (en) 2007-12-20 2009-07-09 Ethicon, Incorporated Encapsulated kidney tissue
HUE035164T2 (en) 2010-11-23 2018-05-02 The Rogosin Inst Inc A method for isolating a cancer cell resistant to a chemotherapeutic agent that exhibits stem cell properties
JP5986226B2 (ja) 2012-01-31 2016-09-06 ザ ロゴシン インスティチュート, インク.The Rogosin Institute, Inc マクロビーズ製造のための改良方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
CA1196862A (en) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
US4997443A (en) * 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
US4902295A (en) * 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
SE8604684L (sv) * 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
US5053332A (en) * 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
US5227298A (en) * 1990-08-17 1993-07-13 The Trustees Of Columbia University In The City Of New York Method for microencapuslation of cells or tissue
ES2260568T3 (es) * 1994-01-13 2006-11-01 The Rogosin Institute Celulas secretoras macroencapsuladas.
CN1157560A (zh) * 1994-07-08 1997-08-20 巴克斯特国际有限公司 用于治疗癌症的装载有肿瘤细胞的可植入装置

Also Published As

Publication number Publication date
CN1769430A (zh) 2006-05-10
US5888497A (en) 1999-03-30
IL126442A (en) 2009-07-20

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