PT1339398E - Tratamento de flutuações motoras - Google Patents
Tratamento de flutuações motoras Download PDFInfo
- Publication number
- PT1339398E PT1339398E PT01976536T PT01976536T PT1339398E PT 1339398 E PT1339398 E PT 1339398E PT 01976536 T PT01976536 T PT 01976536T PT 01976536 T PT01976536 T PT 01976536T PT 1339398 E PT1339398 E PT 1339398E
- Authority
- PT
- Portugal
- Prior art keywords
- hydroxytryptamine
- receptor activity
- treatment
- motor fluctuations
- activity enhancing
- Prior art date
Links
- 102000012306 5-Hydroxytryptamine 1A receptors Human genes 0.000 title abstract 3
- 108050002825 5-Hydroxytryptamine 1A receptors Proteins 0.000 title abstract 3
- 206010030312 On and off phenomenon Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 230000002708 enhancing effect Effects 0.000 title 1
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 238000009256 replacement therapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Processing Of Meat And Fish (AREA)
- Paper (AREA)
- Threshing Machine Elements (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0027020.7A GB0027020D0 (en) | 2000-11-03 | 2000-11-03 | Treatment of movement disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1339398E true PT1339398E (pt) | 2008-11-03 |
Family
ID=9902589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01976536T PT1339398E (pt) | 2000-11-03 | 2001-10-29 | Tratamento de flutuações motoras |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20040067956A1 (pt) |
| EP (1) | EP1339398B1 (pt) |
| JP (2) | JP5189240B2 (pt) |
| AT (1) | ATE406880T1 (pt) |
| AU (2) | AU2001295804B2 (pt) |
| CA (1) | CA2431641A1 (pt) |
| CY (1) | CY1108628T1 (pt) |
| DE (1) | DE60135675D1 (pt) |
| DK (1) | DK1339398T3 (pt) |
| ES (1) | ES2311549T3 (pt) |
| GB (1) | GB0027020D0 (pt) |
| PT (1) | PT1339398E (pt) |
| WO (1) | WO2002036107A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9924941D0 (en) * | 1999-10-22 | 1999-12-22 | Univ Manchester | Treatment of dyskinesia |
| GB0027020D0 (en) | 2000-11-03 | 2000-12-20 | Univ Manchester | Treatment of movement disorders |
| US9066903B2 (en) | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
| PT2908805T (pt) * | 2012-10-22 | 2021-09-10 | Civitas Therapeutics Inc | Formulações de levodopa para alívio rápido da doença de parkinson |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993013766A1 (en) * | 1992-01-07 | 1993-07-22 | Merrell Dow Pharmaceuticals Inc. | Treatment of involuntary movements with 5ht1a receptor agonists |
| EP0697894A4 (en) * | 1993-03-31 | 1996-05-01 | Univ Pennsylvania | DOPAMINE D-3 AND SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS |
| GB9408084D0 (en) * | 1994-04-23 | 1994-06-15 | Boots Co Plc | Medical treatment |
| GB9815618D0 (en) * | 1998-07-18 | 1998-09-16 | Univ Manchester | Treatment of dyskinesia |
| HN1999000146A (es) * | 1998-09-21 | 2000-11-11 | Pfizer Prod Inc | Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas. |
| US6136559A (en) * | 1998-10-07 | 2000-10-24 | Ortho Pharmaceutical Corporation | DNA encoding as human histamine receptor of the H3 subtype |
| GB9924941D0 (en) * | 1999-10-22 | 1999-12-22 | Univ Manchester | Treatment of dyskinesia |
| GB0027020D0 (en) | 2000-11-03 | 2000-12-20 | Univ Manchester | Treatment of movement disorders |
| AU2003267557B2 (en) * | 2002-09-17 | 2009-02-26 | Motac Neuroscience Limited | Treatment of dyskinesia |
| EA015073B1 (ru) | 2006-06-16 | 2011-04-29 | Солвей Фармасьютикалс Б.В. | Комбинированные препараты, содержащие slv308 и l-dopa |
| US7786126B2 (en) * | 2006-06-16 | 2010-08-31 | Solvay Pharmaceuticals B.V. | Combination preparations comprising SLV308 and a dopamine agonist |
| RU2010107036A (ru) | 2007-11-30 | 2011-08-27 | Дайити Санке Компани, Лимитед (Jp) | Лекарственное средство для облегчения двигательных нарушений или психиатрических симптомов при болезни паркинсона |
-
2000
- 2000-11-03 GB GBGB0027020.7A patent/GB0027020D0/en not_active Ceased
-
2001
- 2001-10-29 PT PT01976536T patent/PT1339398E/pt unknown
- 2001-10-29 AU AU2001295804A patent/AU2001295804B2/en not_active Ceased
- 2001-10-29 DE DE60135675T patent/DE60135675D1/de not_active Expired - Lifetime
- 2001-10-29 WO PCT/GB2001/004774 patent/WO2002036107A2/en active IP Right Grant
- 2001-10-29 CA CA002431641A patent/CA2431641A1/en not_active Abandoned
- 2001-10-29 EP EP01976536A patent/EP1339398B1/en not_active Expired - Lifetime
- 2001-10-29 JP JP2002538919A patent/JP5189240B2/ja not_active Expired - Fee Related
- 2001-10-29 US US10/415,817 patent/US20040067956A1/en not_active Abandoned
- 2001-10-29 DK DK01976536T patent/DK1339398T3/da active
- 2001-10-29 ES ES01976536T patent/ES2311549T3/es not_active Expired - Lifetime
- 2001-10-29 AT AT01976536T patent/ATE406880T1/de active
- 2001-10-29 AU AU9580401A patent/AU9580401A/xx active Pending
-
2008
- 2008-12-02 CY CY20081101390T patent/CY1108628T1/el unknown
-
2010
- 2010-07-16 JP JP2010161831A patent/JP2010241827A/ja active Pending
-
2011
- 2011-03-31 US US13/077,478 patent/US9668995B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1339398B1 (en) | 2008-09-03 |
| US20110178178A1 (en) | 2011-07-21 |
| AU2001295804B2 (en) | 2007-01-04 |
| DE60135675D1 (de) | 2008-10-16 |
| CA2431641A1 (en) | 2002-05-10 |
| JP2004512360A (ja) | 2004-04-22 |
| US9668995B2 (en) | 2017-06-06 |
| EP1339398A2 (en) | 2003-09-03 |
| US20040067956A1 (en) | 2004-04-08 |
| JP5189240B2 (ja) | 2013-04-24 |
| ATE406880T1 (de) | 2008-09-15 |
| AU9580401A (en) | 2002-05-15 |
| DK1339398T3 (da) | 2009-01-26 |
| WO2002036107A2 (en) | 2002-05-10 |
| GB0027020D0 (en) | 2000-12-20 |
| WO2002036107A3 (en) | 2003-01-16 |
| ES2311549T3 (es) | 2009-02-16 |
| CY1108628T1 (el) | 2014-04-09 |
| JP2010241827A (ja) | 2010-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1049284A1 (en) | Benzimidazole compounds having nociceptin receptoraffinity | |
| BG108495A (en) | 5-ht receptor ligands and uses thereof | |
| HK1051005A1 (en) | Methods and compositions for modulating alpha adrenergic receptor activity | |
| DE60112974D1 (en) | Carbolinderivate | |
| CR6393A (es) | Moduladores de ccr5 | |
| DE60216233D1 (en) | Carbolinderivate | |
| HK1069171A1 (en) | Substituted 6H-dibenzioÄc,hÜchromenes as estrogenic agents. | |
| HK1068274A1 (en) | Use of 1-phenyl-3-dimethylaminopropane compounds for treating urinary incontinence | |
| MXPA02006167A (es) | Promocion de la angiogenesis con survivina. | |
| HK1061340A1 (en) | Activity control during dieting | |
| CY1108628T1 (el) | Θεραπεια των κινητικων διακυμανσεων με ενωσεις ενισχυσης της δραστηριοτητας του υποδοχεα 5-υδροξυτρυπταμινη 1α | |
| MXPA03010406A (es) | Tratamiento novedoso para el desorden obsesivo-compulsivo (ocd) y desordenes relacionados con ocd. | |
| GB9924941D0 (en) | Treatment of dyskinesia | |
| UA87813C2 (ru) | Система контролируемого высвобождения темозоломида | |
| MXPA04004090A (es) | Compuestos substituidos de 1h-quinolin-2-ona. | |
| WO2002024181A3 (en) | The use of melatonin for induction of general anesthesia | |
| AU2002365288A1 (en) | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases | |
| MXPA04000272A (es) | Derivados de 4-aminociclohexanol sustituidos. | |
| ATE323493T1 (de) | Gesteuerte freisetzung von antidepressiva | |
| EP1406605A4 (en) | 2-HETEROCYCLIC 1,2-ETHANEDIOL CARBAMATES | |
| WO2002007766A8 (en) | Use of d5-dopamine receptor agonists in the manufacture of a medicament for the treatment of dyskinesia | |
| ZA200204455B (en) | Use of dopamine-D3 receptor agonists for the therapy of salt-dependent hypertension. | |
| WO2003070177A3 (en) | Use of melatonin analogues for induction of general anesthesia | |
| UA32278A (uk) | S, o-етилен (о,о-диетилтіофосфорил)-диетилтіофосфат, володіючий інсектицидною активністю | |
| IT1307108B1 (it) | Macchina palissonatrice per pelli. |