PT1311270E - Compostos barbitúricos não sedativos como agentes neuroprotectores - Google Patents
Compostos barbitúricos não sedativos como agentes neuroprotectores Download PDFInfo
- Publication number
- PT1311270E PT1311270E PT01959195T PT01959195T PT1311270E PT 1311270 E PT1311270 E PT 1311270E PT 01959195 T PT01959195 T PT 01959195T PT 01959195 T PT01959195 T PT 01959195T PT 1311270 E PT1311270 E PT 1311270E
- Authority
- PT
- Portugal
- Prior art keywords
- neuroprotective agents
- sedative
- sedating barbiturate
- barbiturate compounds
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22167200P | 2000-07-26 | 2000-07-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1311270E true PT1311270E (pt) | 2008-04-15 |
Family
ID=22828824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01959195T PT1311270E (pt) | 2000-07-26 | 2001-07-26 | Compostos barbitúricos não sedativos como agentes neuroprotectores |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1311270B1 (pt) |
JP (1) | JP5047442B2 (pt) |
CN (2) | CN1329032C (pt) |
AT (1) | ATE383159T1 (pt) |
AU (2) | AU8077801A (pt) |
BR (1) | BR0112775A (pt) |
CA (1) | CA2416535C (pt) |
DE (1) | DE60132337T2 (pt) |
ES (1) | ES2300349T3 (pt) |
HK (1) | HK1100814A1 (pt) |
IL (3) | IL154060A0 (pt) |
MX (1) | MXPA03000824A (pt) |
PT (1) | PT1311270E (pt) |
WO (1) | WO2002007729A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6093820A (en) | 1997-10-02 | 2000-07-25 | Taro Pharmaceutical Industries Ltd. | Method and reagents for N-alkylating ureides |
US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
DE60132337T2 (de) * | 2000-07-26 | 2009-02-12 | Taro Pharmaceutical Industries Ltd. | Nicht-sedierende barbituratverbindungen als neuroprotektive wirkstoffe |
US6939873B2 (en) | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
JP2005516052A (ja) * | 2002-01-30 | 2005-06-02 | タロ ファーマシューティカル インダストリーズ リミテッド | 非鎮静性バルビツール酸誘導体 |
PL219493B1 (pl) * | 2002-10-11 | 2015-05-29 | Baxter International | Zastosowanie kompozycji zawierającej fluorowcowany lotny środek znieczulający oraz kompozycja zawierająca fluorowcowany lotny związek znieczulający do zastosowania w leczeniu pacjenta |
JP4739760B2 (ja) * | 2002-12-11 | 2011-08-03 | タロー・ファーマシューティカル・インダストリーズ・リミテッド | バルビツール酸誘導体を使用する運動障害の治療方法 |
EP1625848A1 (en) * | 2004-08-10 | 2006-02-15 | Taro Pharmaceuticals North America, Inc. | Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid |
WO2013038427A1 (en) * | 2011-09-12 | 2013-03-21 | Council Of Scientific & Industrial Research | ARYLATED β-DICARBOIMYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF |
CN102863579B (zh) * | 2012-09-14 | 2014-02-05 | 东南大学 | 一种巴比妥酸螯合树脂及其制备方法和应用 |
WO2017112025A2 (en) | 2015-10-05 | 2017-06-29 | The University Of North Carolina At Chapel Hill | Decoding methods for multiplexing assays and associated fluidic devices, kits, and solid supports |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL69722A (en) * | 1983-09-14 | 1986-09-30 | Taro Pharma Ind | Oxopyrimidine derivatives and pharmaceutical compositions containing them |
US4833148A (en) * | 1987-04-09 | 1989-05-23 | Washington University | Method of using alkenyl- or alkynyl-substituted thiobarbiturates to reduce neurotoxic injury |
US5474990A (en) * | 1989-10-20 | 1995-12-12 | Olney; John W. | Barbiturates as safening agents in conjunction with NMDA antagonists |
DE60132337T2 (de) * | 2000-07-26 | 2009-02-12 | Taro Pharmaceutical Industries Ltd. | Nicht-sedierende barbituratverbindungen als neuroprotektive wirkstoffe |
-
2001
- 2001-07-26 DE DE60132337T patent/DE60132337T2/de not_active Expired - Lifetime
- 2001-07-26 ES ES01959195T patent/ES2300349T3/es not_active Expired - Lifetime
- 2001-07-26 AU AU8077801A patent/AU8077801A/xx active Pending
- 2001-07-26 BR BR0112775-6A patent/BR0112775A/pt not_active Application Discontinuation
- 2001-07-26 JP JP2002513464A patent/JP5047442B2/ja not_active Expired - Fee Related
- 2001-07-26 EP EP01959195A patent/EP1311270B1/en not_active Expired - Lifetime
- 2001-07-26 CN CNB018151426A patent/CN1329032C/zh not_active Expired - Fee Related
- 2001-07-26 PT PT01959195T patent/PT1311270E/pt unknown
- 2001-07-26 MX MXPA03000824A patent/MXPA03000824A/es active IP Right Grant
- 2001-07-26 CA CA2416535A patent/CA2416535C/en not_active Expired - Fee Related
- 2001-07-26 CN CNB2006100813267A patent/CN100522172C/zh not_active Expired - Fee Related
- 2001-07-26 AU AU2001280778A patent/AU2001280778B2/en not_active Ceased
- 2001-07-26 AT AT01959195T patent/ATE383159T1/de not_active IP Right Cessation
- 2001-07-26 WO PCT/US2001/023420 patent/WO2002007729A1/en active IP Right Grant
- 2001-07-26 IL IL15406001A patent/IL154060A0/xx unknown
-
2003
- 2003-01-20 IL IL154060A patent/IL154060A/en not_active IP Right Cessation
-
2004
- 2004-11-03 IL IL16501704A patent/IL165017A0/xx unknown
-
2007
- 2007-06-05 HK HK07105924.3A patent/HK1100814A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CN1872067A (zh) | 2006-12-06 |
DE60132337D1 (de) | 2008-02-21 |
IL165017A0 (en) | 2005-12-18 |
CN1329032C (zh) | 2007-08-01 |
MXPA03000824A (es) | 2004-11-01 |
DE60132337T2 (de) | 2009-02-12 |
EP1311270A1 (en) | 2003-05-21 |
CA2416535C (en) | 2010-11-16 |
JP5047442B2 (ja) | 2012-10-10 |
CA2416535A1 (en) | 2002-01-31 |
ES2300349T3 (es) | 2008-06-16 |
IL154060A (en) | 2013-05-30 |
IL154060A0 (en) | 2003-07-31 |
AU8077801A (en) | 2002-02-05 |
WO2002007729A1 (en) | 2002-01-31 |
EP1311270A4 (en) | 2006-04-12 |
EP1311270B1 (en) | 2008-01-09 |
HK1100814A1 (en) | 2007-09-28 |
CN1461219A (zh) | 2003-12-10 |
JP2004517808A (ja) | 2004-06-17 |
AU2001280778B2 (en) | 2004-09-02 |
CN100522172C (zh) | 2009-08-05 |
BR0112775A (pt) | 2003-12-30 |
ATE383159T1 (de) | 2008-01-15 |
WO2002007729A9 (en) | 2002-08-08 |
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