PT1098639E - A utilizacao de intensificadores de captacao da glicose para reduzir a apoptose - Google Patents

A utilizacao de intensificadores de captacao da glicose para reduzir a apoptose

Info

Publication number
PT1098639E
PT1098639E PT99934914T PT99934914T PT1098639E PT 1098639 E PT1098639 E PT 1098639E PT 99934914 T PT99934914 T PT 99934914T PT 99934914 T PT99934914 T PT 99934914T PT 1098639 E PT1098639 E PT 1098639E
Authority
PT
Portugal
Prior art keywords
intensifiers
reduce apoptosis
glucose capture
glucose
capture
Prior art date
Application number
PT99934914T
Other languages
English (en)
Portuguese (pt)
Inventor
Antoine M A Bril
Buckingham Robin Edwin
Khandoudi Nassirah
Original Assignee
Smithkline Beecham Plc
Glaxosmithkline Lab Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815872.8A external-priority patent/GB9815872D0/en
Priority claimed from GBGB9815871.0A external-priority patent/GB9815871D0/en
Priority claimed from GBGB9905387.8A external-priority patent/GB9905387D0/en
Application filed by Smithkline Beecham Plc, Glaxosmithkline Lab Sas filed Critical Smithkline Beecham Plc
Publication of PT1098639E publication Critical patent/PT1098639E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT99934914T 1998-07-21 1999-07-21 A utilizacao de intensificadores de captacao da glicose para reduzir a apoptose PT1098639E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9815872.8A GB9815872D0 (en) 1998-07-21 1998-07-21 Novel method
GBGB9815871.0A GB9815871D0 (en) 1998-07-21 1998-07-21 Novel compound
GBGB9905387.8A GB9905387D0 (en) 1999-03-09 1999-03-09 Novel method

Publications (1)

Publication Number Publication Date
PT1098639E true PT1098639E (pt) 2005-06-30

Family

ID=27269407

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99934914T PT1098639E (pt) 1998-07-21 1999-07-21 A utilizacao de intensificadores de captacao da glicose para reduzir a apoptose

Country Status (25)

Country Link
EP (2) EP1098639B1 (enExample)
JP (1) JP2002521326A (enExample)
KR (1) KR20010079551A (enExample)
CN (1) CN1310620A (enExample)
AP (1) AP2001002036A0 (enExample)
AT (1) ATE288746T1 (enExample)
AU (1) AU5053799A (enExample)
BG (1) BG105250A (enExample)
BR (1) BR9912117A (enExample)
CA (1) CA2338211A1 (enExample)
DE (1) DE69923687T2 (enExample)
DK (1) DK1098639T3 (enExample)
EA (1) EA200100165A1 (enExample)
ES (1) ES2237929T3 (enExample)
HU (1) HUP0103199A3 (enExample)
ID (1) ID26986A (enExample)
IL (1) IL140664A0 (enExample)
NO (1) NO20010292L (enExample)
OA (1) OA11579A (enExample)
PL (1) PL345627A1 (enExample)
PT (1) PT1098639E (enExample)
SI (1) SI1098639T1 (enExample)
SK (1) SK1012001A3 (enExample)
TR (1) TR200100207T2 (enExample)
WO (1) WO2000004890A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3073600A (en) * 1999-01-19 2000-08-07 Sankyo Company Limited Inhibitor for nerve cell death due to glutamic acid cytotoxicity
WO2001016120A1 (en) 1999-08-27 2001-03-08 Eli Lilly And Company Biaryl-oxa(thia)zole derivatives and their use as ppars modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (de) * 1987-09-04 2000-05-11 Beecham Group P.L.C., Brentford Substituierte Thiazolidindionderivate
JPH05202042A (ja) * 1992-01-24 1993-08-10 Sankyo Co Ltd 糖尿病性合併症治療剤
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
IL120443A (en) * 1996-03-18 2000-07-16 Sankyo Co Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
US6277819B1 (en) * 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
CN1235543A (zh) * 1996-09-12 1999-11-17 三共株式会社 含有曲格列酮的谷胱甘肽还原酶活性增强剂
GB9721692D0 (en) * 1997-10-13 1997-12-10 Smithkline Beecham Plc Novel treatment
DE69834508T2 (de) * 1997-11-19 2006-11-23 Takeda Pharmaceutical Co. Ltd. Apoptoseinhibitoren
WO1999043326A1 (en) * 1998-02-24 1999-09-02 The Trustees Of The University Of Pennsylvania Use of a cardiac purinoceptor to effect cellular glucose uptake
WO1999059586A1 (en) * 1998-05-19 1999-11-25 Regents Of The University Of California Thiazolidine and oxazolidine derivatives for the treatment of acute myocardial infarction and inhibition of cardiomyocyte apoptosis
US5968960A (en) * 1999-01-14 1999-10-19 The Regents Of The University Of California Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism

Also Published As

Publication number Publication date
ATE288746T1 (de) 2005-02-15
BR9912117A (pt) 2001-04-10
AP2001002036A0 (en) 2001-03-31
HUP0103199A2 (hu) 2002-05-29
KR20010079551A (ko) 2001-08-22
EA200100165A1 (ru) 2001-08-27
HUP0103199A3 (en) 2002-08-28
EP1098639B1 (en) 2005-02-09
CA2338211A1 (en) 2000-02-03
EP1098639A1 (en) 2001-05-16
OA11579A (en) 2004-06-01
DK1098639T3 (da) 2005-06-13
IL140664A0 (en) 2002-02-10
NO20010292D0 (no) 2001-01-18
DE69923687T2 (de) 2006-04-06
AU5053799A (en) 2000-02-14
DE69923687D1 (de) 2005-03-17
ID26986A (id) 2001-02-22
NO20010292L (no) 2001-03-08
SK1012001A3 (en) 2001-08-06
HK1037865A1 (en) 2002-02-22
PL345627A1 (en) 2002-01-02
WO2000004890A1 (en) 2000-02-03
EP1516617A2 (en) 2005-03-23
TR200100207T2 (tr) 2001-05-21
SI1098639T1 (enExample) 2005-08-31
CN1310620A (zh) 2001-08-29
ES2237929T3 (es) 2005-08-01
JP2002521326A (ja) 2002-07-16
BG105250A (en) 2001-11-30

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