PT1012149E - Metabolito de todo-trans-retinol - Google Patents
Metabolito de todo-trans-retinolInfo
- Publication number
- PT1012149E PT1012149E PT98935523T PT98935523T PT1012149E PT 1012149 E PT1012149 E PT 1012149E PT 98935523 T PT98935523 T PT 98935523T PT 98935523 T PT98935523 T PT 98935523T PT 1012149 E PT1012149 E PT 1012149E
- Authority
- PT
- Portugal
- Prior art keywords
- retinol
- metabolite
- trans
- atrol
- vad
- Prior art date
Links
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 title abstract 2
- 239000002207 metabolite Substances 0.000 title abstract 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 5
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 3
- 239000011717 all-trans-retinol Substances 0.000 abstract 2
- 229940100609 all-trans-retinol Drugs 0.000 abstract 2
- 235000019169 all-trans-retinol Nutrition 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 230000035935 pregnancy Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 230000037380 skin damage Effects 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 229940045997 vitamin a Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/927,511 US5880292A (en) | 1997-09-11 | 1997-09-11 | All-trans-retinol metabolite |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1012149E true PT1012149E (pt) | 2003-01-31 |
Family
ID=25454835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98935523T PT1012149E (pt) | 1997-09-11 | 1998-07-01 | Metabolito de todo-trans-retinol |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5880292A (pt) |
| EP (1) | EP1012149B1 (pt) |
| AT (1) | ATE224886T1 (pt) |
| AU (1) | AU8475498A (pt) |
| DE (1) | DE69808316T2 (pt) |
| DK (1) | DK1012149T3 (pt) |
| ES (1) | ES2180189T3 (pt) |
| PT (1) | PT1012149E (pt) |
| WO (1) | WO1999012922A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743222B2 (en) | 1999-12-10 | 2004-06-01 | Candela Corporation | Method of treating disorders associated with sebaceous follicles |
| US20080091179A1 (en) * | 1999-12-10 | 2008-04-17 | Candela Corporation | Compact, handheld device for home-based acne treatment |
| US8404667B2 (en) * | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
| US8246611B2 (en) * | 2006-06-14 | 2012-08-21 | Candela Corporation | Treatment of skin by spatial modulation of thermal heating |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190594A (en) * | 1975-11-03 | 1980-02-26 | Johnson & Johnson | Retinoic acid derivatives |
| DE3002545A1 (de) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 5-amino-tetrazol-derivate von retinsaeuren, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| US4568757A (en) * | 1984-01-30 | 1986-02-04 | Research Triangle Institute | Configurationally locked retinoids |
| US4757140A (en) * | 1986-06-02 | 1988-07-12 | Wisconsin Alumni Research Foundation | Coenzyme a derivatives of all-trans- and 13-cis retionic acid |
| DE4116656A1 (de) * | 1991-02-13 | 1992-08-20 | Nattermann A & Cie | 2-((omega)-arylalkyl)-3-thienyl -alkansaeuren, ihre salze uund/oder ihre derivate |
| DE4116655A1 (de) * | 1991-02-13 | 1992-08-20 | Nattermann A & Cie | (3-((omega)-arylalkyl)-2-thienyl)alkansaeure, ihre salze und/oder ihre derivate |
| DE4118014A1 (de) * | 1991-06-01 | 1992-12-03 | Rhone Poulenc Rorer Gmbh | (4-((omega)-arylalkyl)-2-thienyl)alkansaeuren, ihre salze und/oder ihre derivate |
| DE4118173A1 (de) * | 1991-06-03 | 1992-12-10 | Rhone Poulenc Rorer Gmbh | (5-((omega)arylalkyl)-3-thienyl)alkansaeuren, ihre salze und/oder ihre derivate |
-
1997
- 1997-09-11 US US08/927,511 patent/US5880292A/en not_active Expired - Fee Related
-
1998
- 1998-07-01 WO PCT/US1998/013788 patent/WO1999012922A1/en not_active Ceased
- 1998-07-01 AU AU84754/98A patent/AU8475498A/en not_active Abandoned
- 1998-07-01 PT PT98935523T patent/PT1012149E/pt unknown
- 1998-07-01 AT AT98935523T patent/ATE224886T1/de not_active IP Right Cessation
- 1998-07-01 ES ES98935523T patent/ES2180189T3/es not_active Expired - Lifetime
- 1998-07-01 EP EP98935523A patent/EP1012149B1/en not_active Expired - Lifetime
- 1998-07-01 DE DE69808316T patent/DE69808316T2/de not_active Expired - Fee Related
- 1998-07-01 DK DK98935523T patent/DK1012149T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2180189T3 (es) | 2003-02-01 |
| AU8475498A (en) | 1999-03-29 |
| DK1012149T3 (da) | 2002-10-14 |
| DE69808316D1 (de) | 2002-10-31 |
| ATE224886T1 (de) | 2002-10-15 |
| DE69808316T2 (de) | 2003-01-23 |
| EP1012149A1 (en) | 2000-06-28 |
| WO1999012922A1 (en) | 1999-03-18 |
| US5880292A (en) | 1999-03-09 |
| EP1012149B1 (en) | 2002-09-25 |
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