PL56591B1 - - Google Patents

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Publication number
PL56591B1
PL56591B1 PL116018A PL11601866A PL56591B1 PL 56591 B1 PL56591 B1 PL 56591B1 PL 116018 A PL116018 A PL 116018A PL 11601866 A PL11601866 A PL 11601866A PL 56591 B1 PL56591 B1 PL 56591B1
Authority
PL
Poland
Prior art keywords
benzene
reaction
earth metal
alkaline earth
environment
Prior art date
Application number
PL116018A
Other languages
Polish (pl)
Inventor
Przemyslaw Lenkowsjd dr
Halina Cieslik mgr
Goncz Janina
Kurpiel Janina
Original Assignee
Jeleniogórskie Zaklady Farmaceutyczne „Polfa"Przedsiebiorstwo Panstwowe
Filing date
Publication date
Application filed by Jeleniogórskie Zaklady Farmaceutyczne „Polfa"Przedsiebiorstwo Panstwowe filed Critical Jeleniogórskie Zaklady Farmaceutyczne „Polfa"Przedsiebiorstwo Panstwowe
Publication of PL56591B1 publication Critical patent/PL56591B1/pl

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Description

Przyklad II. Postepuje sie jak w przykladzie 25 1, z ta róznica, ze reakcje prowadzi sie w miesza¬ ninie 55 ml 96% alkoholu etylowego i 15 ml ben¬ zenu. 80 PLExample II. The procedure is as in Example 25 1, with the difference that the reaction is carried out in a mixture of 55 ml of 96% ethanol and 15 ml of benzene. 80 PL

Claims (1)

1. Zastrzezenie patentowe Sposób redukcji grupy ketonowej octanu andro¬ stenolonu za pomoca borowodorku sodu w tempe¬ raturze do 10°C, w srodowisku alkoholu, ma- 35 mienny tym, ze reakcje prowadzi sie w obecnosci soli metali ziem alkalicznych, korzystnie chlorku wapniowego, tworzacych podczas reakcji z bono* wodorkiem sodowym odpowiednie borowodorki metali ziem alkalicznych, w srodowisku 96% alko¬ wo holu etylowego, ewentualnie w mieszaninie z ben¬ zenem lub z benzenem i metanolem. CHtCOO OH CACOO KZG-3, zam. 1642/68 — 220 PLClaim 1. A method of reducing the ketone group of androstenolone acetate with sodium borohydride at a temperature of up to 10 ° C in an alcoholic environment, alternating the reaction in the presence of an alkaline earth metal salt, preferably calcium chloride, the corresponding alkaline earth metal borohydrides formed during the reaction with sodium bono hydride in an environment of 96% alcohol ethanol, optionally in a mixture with benzene or with benzene and methanol. CHtCOO OH CACOO KZG-3, order 1642/68 - 220 PL
PL116018A 1966-08-08 PL56591B1 (en)

Publications (1)

Publication Number Publication Date
PL56591B1 true PL56591B1 (en) 1968-12-27

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