PL55123B1 - - Google Patents
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- Publication number
- PL55123B1 PL55123B1 PL114945A PL11494566A PL55123B1 PL 55123 B1 PL55123 B1 PL 55123B1 PL 114945 A PL114945 A PL 114945A PL 11494566 A PL11494566 A PL 11494566A PL 55123 B1 PL55123 B1 PL 55123B1
- Authority
- PL
- Poland
- Prior art keywords
- imine
- formula
- acid
- moles
- nnrr4
- Prior art date
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- 150000002466 imines Chemical class 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 claims 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- HLHNOIAOWQFNGW-UHFFFAOYSA-N 3-bromo-4-hydroxybenzonitrile Chemical compound OC1=CC=C(C#N)C=C1Br HLHNOIAOWQFNGW-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Chemical group 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 125000005265 dialkylamine group Chemical group 0.000 claims 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 1
- 235000005985 organic acids Nutrition 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 claims 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Description
Postepujac dalej jak w poprzednich przykladach otrzymuje sie 3,9 g dwu- chlorowodorku N-[N'-(a-p-metoksyfenylo-#, /?, fi- trójchloroetylo) aminoetylo]-morfoliny, który po so wytraceniu z alkoholu topi sie w temperaturze 182,5°—184° (z rozkladem) i wysuszony w tempera¬ turze pokojowej zawiera wode krystalizacyjna.Analiza: znaleziono C-39,8°/o, H-5,55°/o, N-6,3%; obliczono dla C15H23ONCI5 • 1V2H20 — C-39,9 35 H-5,75°/t N-6,2Vo. PL
Claims (3)
- Zastrzezenia patentowe 1. Sposób wytwarzania pochodnych III-rzedowych 40 (aminoalkilo)-amin o wzorze 1, w którym X oznacza atom chloru lub bromu, Ar oznacza reszte aromatyczna* n jest równe lub wieksze od 2, a NRR1 oznacza reszte dwualkiloaminy lub cyklicznej aminy II-rzedowej jak pirolidy- 49 na, piperydyna lub morfolina znamienny tym, ze imine o wzorze 2, w którym Ar, n i NRR* maja znacznie wyzej podane, poddaje sie re¬ akcji z kwasem trójchlorooctowym lub trój- bromooctowym w srodowisku rozpuszczalnika 50 organicznego.
- 2. Sposób wedlug zastrz. 1, znamienny tym, ze na 1 mol iminy o wzorze 2 stosuje sie dwa lub wie¬ cej moli kwasu trójchlorowcooctowego.
- 3. Odmiana sposobu wedlug zastrz. 1, znamienna 55 tym, ze na imine o wzorze 2 dziala sie miesza¬ nina kwasów organicznych zawierajaca w sto¬ sunku do 1 mola iminy 1—2 mole kwasu trój¬ chlorowcooctowego oraz 1—2 mole innego kwa¬ su organicznego.KI. 12 q, 1/01 55 123 MKP C 07 o CX3 Wiór 1 ArCH'N/CH2/nNRR4 W2Ór2 ArCH-N/CM^nMftR1 ^SCK^COOH^ ArCHNH/CH2/nNRR4 * CO^ W 3 SCHEMAT 1 PL
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL55123B1 true PL55123B1 (pl) | 1968-02-26 |
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