PL447745A1 - Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego - Google Patents

Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego

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PL447745A1
PL447745A1 PL447745A PL44774524A PL447745A1 PL 447745 A1 PL447745 A1 PL 447745A1 PL 447745 A PL447745 A PL 447745A PL 44774524 A PL44774524 A PL 44774524A PL 447745 A1 PL447745 A1 PL 447745A1
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Poland
Prior art keywords
succinic acid
microbial metabolites
especially succinic
biosynthesizing
subject
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PL447745A
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English (en)
Inventor
Marcin Podleśny
Lech Schimmelpfennig
Jagoda Kucharska
Tomasz Szymczak
Monika Szymajda
Wojciech Antosz
Bartosz Bednarz
Tomasz LIPIŃSKI
Original Assignee
Grupa Azoty Zakłady Azotowe Puławy Spółka Akcyjna
Sieć Badawcza Łukasiewicz - PORT Polski Ośrodek Rozwoju Technologii
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Priority to PL447745A priority Critical patent/PL447745A1/pl
Publication of PL447745A1 publication Critical patent/PL447745A1/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Przedmiotem zgłoszenia jest nowo wyizolowany szczep bakteryjny Enterobacter sp. GAP1 należący do rodziny Enterobacteriaceae, zdeponowany w Polskiej Kolekcji Mikroorganizmów, Instytut Immunologii i Terapii Doświadczalnej, Polska Akademia Nauk, ul. Rudolfa Weigla 12, 53-114 Wrocław, pod numerem B/00502, zdolny do biosyntezy metabolitów mikrobiologicznych z grupy obejmującej kwas bursztynowy, kwas mlekowy, 2,3-butanodiol lub ich mieszaniny, zwłaszcza do syntezy kwasu bursztynowego, a także każdy wariant lub mutant otrzymany z wykorzystaniem w/w szczepu. Przedmiotem zgłoszenia są także mutanty otrzymane z wykorzystaniem metod inżynierii genetycznej, wykazujące zdolność do biosyntezy wspomnianych metabolitów mikrobiologicznych na podłożach zawierających sacharydy z wydajnościami przekraczającymi wydajności uzyskiwane z zastosowaniem wspomnianego szczepu GAP1. Przedmiotem zgłoszenia są także sposoby wytwarzania metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, wykorzystujące w/w szczep bakteryjny, jego warianty lub mutanty.
PL447745A 2024-02-12 2024-02-12 Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego PL447745A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL447745A PL447745A1 (pl) 2024-02-12 2024-02-12 Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL447745A PL447745A1 (pl) 2024-02-12 2024-02-12 Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego

Publications (1)

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PL447745A1 true PL447745A1 (pl) 2025-08-18

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PL447745A PL447745A1 (pl) 2024-02-12 2024-02-12 Nowe szczepy bakteryjne, zdolne do biosyntezy metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego, a także sposoby produkcji metabolitów mikrobiologicznych, zwłaszcza kwasu bursztynowego

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PL (1) PL447745A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101348775A (zh) * 2008-09-02 2009-01-21 清华大学 肠杆菌重组菌及其应用
US20120129233A1 (en) * 2009-05-27 2012-05-24 Yoshinori Tajima Method for producing an organic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101348775A (zh) * 2008-09-02 2009-01-21 清华大学 肠杆菌重组菌及其应用
US20120129233A1 (en) * 2009-05-27 2012-05-24 Yoshinori Tajima Method for producing an organic acid

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chemia i biznes; https://www.chemiaibiznes.com.pl/artykuly/w-pulawach-pracuja-nad-produkcja-kwasu-bursztynowego; W Puławach pracują nad produkcją kwasu bursztynowego.; 18.12.2018 *
PODLEŚNY M. I IN.,: "Microb Biotechnol. 2017 Mar; 10(2): 492-501", ENTEROBACTER SP. LU1 AS A NOVEL SUCCINIC ACID PRODUCER - CO-UTILIZATION OF GLYCEROL AND LACTOSE, DOI: 10.1111/1751-7915.12458. Epub 2016 Dec 1. PMID: 27910262; PMCID: PMC5328818 *

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