PL441076A1 - Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie - Google Patents

Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie

Info

Publication number
PL441076A1
PL441076A1 PL441076A PL44107622A PL441076A1 PL 441076 A1 PL441076 A1 PL 441076A1 PL 441076 A PL441076 A PL 441076A PL 44107622 A PL44107622 A PL 44107622A PL 441076 A1 PL441076 A1 PL 441076A1
Authority
PL
Poland
Prior art keywords
application
covalent complex
protein
subject matter
functional covalent
Prior art date
Application number
PL441076A
Other languages
English (en)
Polish (pl)
Inventor
Stanisław Malicki
Grzegorz Dubin
Piotr MYDEL
Joanna Kozieł
Barbara Pucelik
Edyta ŻYŁA
Małgorzata BENEDYK-MACHACZKA
Anna GOLDA
Wojciech GAŁAN
Marta KAMIŃSKA
Barbara CHRUŚCICKA-SMAGA
Alicja Sochaj-Gregorczyk
Katarzyna MAGIERA-MULARZ
Anna CZARNA
Original Assignee
Uniwersytet Jagielloński
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Jagielloński filed Critical Uniwersytet Jagielloński
Priority to PL441076A priority Critical patent/PL441076A1/pl
Priority to PCT/PL2023/050030 priority patent/WO2023211299A1/fr
Publication of PL441076A1 publication Critical patent/PL441076A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3517—Marker; Tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL441076A 2022-04-30 2022-04-30 Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie PL441076A1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL441076A PL441076A1 (pl) 2022-04-30 2022-04-30 Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie
PCT/PL2023/050030 WO2023211299A1 (fr) 2022-04-30 2023-05-02 Aptamère d'adn ayant une affinité pour la protéine pd-l1 et son utilisation, complexe covalent fonctionnel et son utilisation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL441076A PL441076A1 (pl) 2022-04-30 2022-04-30 Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie

Publications (1)

Publication Number Publication Date
PL441076A1 true PL441076A1 (pl) 2023-11-06

Family

ID=87136360

Family Applications (1)

Application Number Title Priority Date Filing Date
PL441076A PL441076A1 (pl) 2022-04-30 2022-04-30 Aptamer DNA wykazujący powinowactwo do białka PD-L1 i jego zastosowanie, funkcjonalny kompleks kowalencyjny oraz jego zastosowanie

Country Status (2)

Country Link
PL (1) PL441076A1 (fr)
WO (1) WO2023211299A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107794268B (zh) * 2017-03-14 2021-03-26 湖南大学 检测人pdl1蛋白的核酸适体及其在制备检测制剂中的应用
CN108929874B (zh) * 2018-07-11 2021-12-14 安徽省昂普拓迈生物科技有限责任公司 一种特异性结合高表达pdl1蛋白的细胞的核酸适配体及其应用
AU2020414184A1 (en) * 2019-12-27 2022-07-14 Interoligo Corporation. Anti-cancer immunotherapeutic composition for treating cancer
WO2022000330A1 (fr) * 2020-06-30 2022-01-06 首都师范大学 Procédé de criblage d'aptamère d'adn de pd-l1 in vitro et application associée dans le diagnostic du cancer

Also Published As

Publication number Publication date
WO2023211299A1 (fr) 2023-11-02

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