PL438510A1 - Method for preparing 5,7,4'-trihydroxy-8-methoxyflavone - Google Patents
Method for preparing 5,7,4'-trihydroxy-8-methoxyflavoneInfo
- Publication number
- PL438510A1 PL438510A1 PL438510A PL43851021A PL438510A1 PL 438510 A1 PL438510 A1 PL 438510A1 PL 438510 A PL438510 A PL 438510A PL 43851021 A PL43851021 A PL 43851021A PL 438510 A1 PL438510 A1 PL 438510A1
- Authority
- PL
- Poland
- Prior art keywords
- methoxyflavone
- trihydroxy
- preparing
- thomi
- pennicilium
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Wynalazek dotyczy sposobu wytwarzania 5,7,4'-trihydroksy-8-metoksyflawonu o wzorze 2. Postępując zgodnie z wynalazkiem, w wyniku działania układu enzymatycznego zawartego w komórkach szczepu Pennicilium thomi AM91, następuje regioselektywna hydroksylacja pierścienia aromatycznego w substracie. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą.The invention relates to a method for the production of 5,7,4'-trihydroxy-8-methoxyflavone of the formula 2. Following the invention, regioselective hydroxylation of the aromatic ring in the substrate occurs as a result of the action of the enzyme system contained in the cells of the Pennicilium thomi AM91 strain. The product thus obtained is isolated from the aqueous culture of the micro-organism in a known manner by extraction with a water-immiscible organic solvent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL438510A PL244025B1 (en) | 2021-07-16 | 2021-07-16 | Method for preparing 5,7,4'-trihydroxy-8-methoxyflavone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL438510A PL244025B1 (en) | 2021-07-16 | 2021-07-16 | Method for preparing 5,7,4'-trihydroxy-8-methoxyflavone |
Publications (2)
Publication Number | Publication Date |
---|---|
PL438510A1 true PL438510A1 (en) | 2023-01-23 |
PL244025B1 PL244025B1 (en) | 2023-11-20 |
Family
ID=84982767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL438510A PL244025B1 (en) | 2021-07-16 | 2021-07-16 | Method for preparing 5,7,4'-trihydroxy-8-methoxyflavone |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL244025B1 (en) |
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2021
- 2021-07-16 PL PL438510A patent/PL244025B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL244025B1 (en) | 2023-11-20 |
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