PL437711A1 - Method for preparing (-)-isomer of 3-hydroxy-3-butylphthalide - Google Patents
Method for preparing (-)-isomer of 3-hydroxy-3-butylphthalideInfo
- Publication number
- PL437711A1 PL437711A1 PL437711A PL43771121A PL437711A1 PL 437711 A1 PL437711 A1 PL 437711A1 PL 437711 A PL437711 A PL 437711A PL 43771121 A PL43771121 A PL 43771121A PL 437711 A1 PL437711 A1 PL 437711A1
- Authority
- PL
- Poland
- Prior art keywords
- butylphthalide
- isomer
- hydroxy
- preparing
- water
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Furan Compounds (AREA)
Abstract
Wynalazek dotyczy sposobu wytwarzania (-)-izomeru 3-hydroksy-3-butyloftalidu o wzorze 2. Postępując zgodnie z wynalazkiem, w wyniku działania enzymów pochodzących z komórek szczepu Chaetomium indicum AM 158, następuje addycja cząsteczki wody do wiązania podwójnego w łańcuchu bocznym 3-n-butylidenoftalidu. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (octan etylu).The invention relates to a method for the production of the (-)-isomer of 3-hydroxy-3-butylphthalide of the formula 2. Following the invention, as a result of the action of enzymes derived from cells of the strain Chaetomium indicum AM 158, the addition of a water molecule to the double bond in the 3- n-butylidenephthalide. The product thus obtained is isolated from the aqueous culture of the micro-organism in a known manner by extraction with a water-immiscible organic solvent (ethyl acetate).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL437711A PL242601B1 (en) | 2021-04-27 | 2021-04-27 | Method for preparing (-)-isomer of 3-hydroxy-3-butylphthalide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL437711A PL242601B1 (en) | 2021-04-27 | 2021-04-27 | Method for preparing (-)-isomer of 3-hydroxy-3-butylphthalide |
Publications (2)
Publication Number | Publication Date |
---|---|
PL437711A1 true PL437711A1 (en) | 2022-10-31 |
PL242601B1 PL242601B1 (en) | 2023-03-20 |
Family
ID=83852885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL437711A PL242601B1 (en) | 2021-04-27 | 2021-04-27 | Method for preparing (-)-isomer of 3-hydroxy-3-butylphthalide |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL242601B1 (en) |
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2021
- 2021-04-27 PL PL437711A patent/PL242601B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL242601B1 (en) | 2023-03-20 |
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